The Set3/Hos2 histone deacetylase complex attenuates cAMP/PKA signaling to regulate morphogenesis and virulence of Candida albicans (Q28473928)

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2 February 2020

title

The Set3/Hos2 histone deacetylase complex attenuates cAMP/PKA signaling to regulate morphogenesis and virulence of Candida albicans (English)

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2 February 2020

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2 February 2020

Karl Kuchler

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2 February 2020

author name string

Olivia Majer

2

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2 February 2020

Ingrid E Frohner

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2 February 2020

Vukoslav Komnenovic

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2 February 2020

language of work or name

English

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publication date

13 May 2010

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2 February 2020

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2 February 2020

volume

6

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issue

5

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2 February 2020

page(s)

e1000889

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Creative Commons Attribution 4.0 International

2 February 2020

copyright license

start time

13 May 2010

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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The S. cerevisiae SET3 complex includes two histone deacetylases, Hos2 and Hst1, and is a meiotic-specific repressor of the sporulation gene program

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19 March 2017

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Nonfilamentous C. albicans Mutants Are Avirulent

19 March 2017

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Efg1-mediated recruitment of NuA4 to promoters is required for hypha-specific Swi/Snf binding and activation in Candida albicans

29 September 2017

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Histone deacetylase inhibitors may reduce pathogenicity and virulence in Candida albicans

29 September 2017

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Environmental sensing and signal transduction pathways regulating morphopathogenic determinants of Candida albicans

29 September 2017

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Morphogenesis in Candida albicans

29 September 2017

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Bistable expression of WOR1, a master regulator of white-opaque switching in Candida albicans

29 September 2017

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Candida albicans SET1 encodes a histone 3 lysine 4 methyltransferase that contributes to the pathogenesis of invasive candidiasis

29 September 2017

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Hos2 and Set3 promote integration of Ty1 retrotransposons at tRNA genes in Saccharomyces cerevisiae

29 September 2017

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The Sho1 adaptor protein links oxidative stress to morphogenesis and cell wall biosynthesis in the fungal pathogen Candida albicans.

29 September 2017

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A contact-activated kinase signals Candida albicans invasive growth and biofilm development

29 September 2017

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Strains and strategies for large-scale gene deletion studies of the diploid human fungal pathogen Candida albicans

29 September 2017

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The distinct morphogenic states of Candida albicans

29 September 2017

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29 September 2017

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29 September 2017

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Superoxide Dismutases inCandida albicans: Transcriptional Regulation and Functional Characterization of the Hyphal-inducedSOD5Gene

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Histone deacetylase inhibitors enhance Candida albicans sensitivity to azoles and related antifungals: correlation with reduction in CDR and ERG upregulation

29 September 2017

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White-opaque switching in Candida albicans is controlled by mating-type locus homeodomain proteins and allows efficient mating

29 September 2017

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29 September 2017

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Linking fungal morphogenesis with virulence

29 September 2017

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Transcriptional control of dimorphism in Candida albicans

29 September 2017

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NRG1, a repressor of filamentous growth in C.albicans, is down-regulated during filament induction

29 September 2017

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NRG1 represses yeast-hypha morphogenesis and hypha-specific gene expression in Candida albicans

29 September 2017

1 reference

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Rfg1, a protein related to the Saccharomyces cerevisiae hypoxic regulator Rox1, controls filamentous growth and virulence in Candida albicans

29 September 2017

1 reference

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Identification and characterization of TUP1-regulated genes in Candida albicans

29 September 2017

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Transcription factors in Candida albicans - environmental control of morphogenesis

29 September 2017

1 reference

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TUP1, CPH1 and EFG1 make independent contributions to filamentation in candida albicans

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2869326

Misexpression of the opaque-phase-specific gene PEP1 (SAP1) in the white phase of Candida albicans confers increased virulence in a mouse model of cutaneous infection

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2869326

HWP1 functions in the morphological development of Candida albicans downstream of EFG1, TUP1, and RBF1.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2869326

Regulatory networks controlling Candida albicans morphogenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2869326

Misexpression of the white-phase-specific gene WH11 in the opaque phase of Candida albicans affects switching and virulence

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2869326

Cloning and characterization of ECE1, a gene expressed in association with cell elongation of the dimorphic pathogen Candida albicans.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2869326

"White-opaque transition": a second high-frequency switching system in Candida albicans

29 September 2017

1 reference

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Effects of low concentrations of zinc on the growth and dimorphism of Candida albicans: evidence for zinc-resistant and -sensitive pathways for mycelium formation

29 September 2017

1 reference

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Transcriptional loops meet chromatin: a dual-layer network controls white-opaque switching in Candida albicans

29 September 2017

1 reference

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2 June 2018

1 reference

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Control of filament formation in Candida albicans by the transcriptional repressor TUP1.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2869326

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2 June 2018

1 reference

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2 June 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1000889

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21 January 2018

1 reference

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Nicotinic acid limitation regulates silencing of Candida adhesins during UTI.

21 January 2018

1 reference

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The SAT1 flipper, an optimized tool for gene disruption in Candida albicans

21 January 2018

1 reference

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Interscience Conference on Antimicrobial Agents and Chemotherapy--49th annual meeting. Part 1. 11-15 September 2009, San Francisco, CA, USA.

21 January 2018

1 reference

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Genetic and biochemical evidence that trehalase is a substrate of cAMP-dependent protein kinase in yeast

27 November 2018

1 reference

12 December 2020

Isolation of the Candida albicans gene for orotidine-5'-phosphate decarboxylase by complementation of S. cerevisiae ura3 and E. coli pyrF mutations

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12 December 2020

Distinct and redundant roles of the two protein kinase A isoforms Tpk1p and Tpk2p in morphogenesis and growth of Candida albicans

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12 December 2020

Ssn6, an important factor of morphological conversion and virulence in Candida albicans

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12 December 2020

Adaptation of the Efg1p morphogenetic pathway in Candida albicans by negative autoregulation and PKA-dependent repression of the EFG1 gene

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12 December 2020

N-acetyl-D-glucosamine induces germination in Candida albicans through a mechanism sensitive to inhibitors of cAMP-dependent protein kinase

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12 December 2020

10.1371/JOURNAL.PPAT.1000889

Identifiers

DOI

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20485517%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20485517%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

PubMed publication ID

20485517

2 references