Statins impair antitumor effects of rituximab by inducing conformational changes of CD20 (Q28472420)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18366248%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

title

Statins impair antitumor effects of rituximab by inducing conformational changes of CD20 (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18366248%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18366248%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Grzegorz Wilczyński

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18366248%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Małgorzata Lekka

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18366248%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Tomasz Stokłosa

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18366248%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Dominika Nowis

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18366248%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Eliza Głodkowska-Mrówka

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18366248%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Tadeusz Issat

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18366248%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Anna Dabrowska-Iwanicka

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18366248%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Krzysztof Warzocha

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18366248%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Maciej Siński

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18366248%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Paul Whi Parren

25

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18366248%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Jakub Gołąb

26

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18366248%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

19

Grzegorz W Basak

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18366248%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

24

Marek Jakobisiak

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18366248%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

23

Zbigniew Gaciong

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18366248%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

1

Magdalena Winiarska

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18366248%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

12

Zuzanna Kurzaj

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18366248%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

17

Witold Lasek

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18366248%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

20

Maria Wasik

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18366248%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

author name string

Ewa Wilczek

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18366248%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Patrick J Engelberts

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18366248%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Wendy J M Mackus

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18366248%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Elzbieta Gorska

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18366248%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Lukasz Bojarski

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18366248%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Marcin Makowski

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18366248%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Piotr Mrowka

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18366248%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

language of work or name

English

0 references

publication date

1 March 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18366248%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18366248%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

volume

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18366248%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18366248%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

page(s)

e64

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18366248%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

4 January 2020

copyright license

start time

25 March 2008

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Pleiotropic effects of statins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270297

The biology of CD20 and its potential as a target for mAb therapy

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270297

A cholesterol-dependent CD20 epitope detected by the FMC7 antibody

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270297

A microcantilever device to assess the effect of force on the lifetime of selectin-carbohydrate bonds

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270297

Rituximab-induced inhibition of antiapoptotic cell survival pathways: implications in chemo/immunoresistance, rituximab unresponsiveness, prognostic and novel therapeutic interventions

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270297

Monoclonal antibody and intravenous immunoglobulin therapy for rheumatic diseases: rationale and mechanisms of action.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270297

Pleiotropic effects of statins and related pharmacological experimental approaches

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270297

B-cell targeted therapies in rheumatoid arthritis and systemic lupus erythematosus

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270297

Rituximab for the treatment of diffuse large B-cell lymphomas

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270297

Statin-associated pleiotropy: possible beneficial effects beyond cholesterol reduction

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270297

The biological activity of human CD20 monoclonal antibodies is linked to unique epitopes on CD20.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270297

The epitope recognized by rituximab

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270297

Dose-finding study of high-dose simvastatin combined with standard chemotherapy in patients with relapsed or refractory myeloma or lymphoma.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270297

Proapoptotic and antitumor activities of the HMG-CoA reductase inhibitor, lovastatin, against Dalton's lymphoma ascites tumor in mice.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270297

29 September 2017

Isoprenylated proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270297

Cholesterol targeting alters lipid raft composition and cell survival in prostate cancer cells and xenografts

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270297

Rituxan (anti-CD20 antibody)-induced translocation of CD20 into lipid rafts is crucial for calcium influx and apoptosis.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270297

Intramembrane aspartic acid in SCAP protein governs cholesterol-induced conformational change

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270297

Expression of prostate specific membrane antigen in androgen-independent prostate cancer cell line PC-3.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270297

Lovastatin potentiates antitumor effects of saquinavir against human lymphoma cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270297

Berberine is a novel cholesterol-lowering drug working through a unique mechanism distinct from statins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270297

From the bench to the bedside: ways to improve rituximab efficacy.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270297

Simvastatin induces apoptosis of Epstein-Barr virus (EBV)-transformed lymphoblastoid cell lines and delays development of EBV lymphomas.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270297

Depletion of cellular cholesterol and lipid rafts increases shedding of CD30.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270297

Protein geranylgeranylation is critical for the regulation of survival and proliferation of lymphoma tumor cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270297

Potential antitumor effects of statins (Review).

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270297

Complement-mediated lysis by anti-CD20 mAb correlates with segregation into lipid rafts

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270297

Statin-induced expression of decay-accelerating factor protects vascular endothelium against complement-mediated injury

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270297

Cholesterol addition to ER membranes alters conformation of SCAP, the SREBP escort protein that regulates cholesterol metabolism

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270297

Who should receive HMG CoA reductase inhibitors?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270297

Regulation of receptor function by cholesterol.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270297

Rapid Redistribution of CD20 to a Low Density Detergent-insoluble Membrane Compartment

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270297

Statin-induced expression of CD59 on vascular endothelium in hypoxia: a potential mechanism for the anti-inflammatory actions of statins in rheumatoid arthritis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270297

Cholesterol depletion inhibits src family kinase-dependent calcium mobilization and apoptosis induced by rituximab crosslinking

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270297

Statin use and risk of lymphoid neoplasms: results from the European Case-Control Study EPILYMPH.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270297

Use of hydroxy-methyl-glutaryl coenzyme A reductase inhibitors is associated with risk of lymphoid malignancies.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270297

Update on treatment recommendations from the Third International Workshop on Waldenstrom's macroglobulinemia

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270297

Pharmacodynamic effects of high dose lovastatin in subjects with advanced malignancies

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270297

Antitumor effects of photodynamic therapy are potentiated by 2-methoxyestradiol. A superoxide dismutase inhibitor.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270297

Alterations in membrane cholesterol that affect structure and function of caveolae

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270297

Alanine-170 and proline-172 are critical determinants for extracellular CD20 epitopes; heterogeneity in the fine specificity of CD20 monoclonal antibodies is defined by additional requirements imposed by both amino acid sequence and quaternary struc

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270297

Rituximab chimeric anti-CD20 monoclonal antibody therapy for relapsed indolent lymphoma: half of patients respond to a four-dose treatment program.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270297

Modulation of complement lysis of human erythrocytes by the membrane lipid viscosity

27 November 2018

1 reference

12 December 2020

Alteration of the myometrial plasma membrane cholesterol content with beta-cyclodextrin modulates the binding affinity of the oxytocin receptor

1 reference

12 December 2020

Identification of a cytoplasmic region of CD20 required for its redistribution to a detergent-insoluble membrane compartment

1 reference

12 December 2020

Rituximab: a review of its use in non-Hodgkin's lymphoma and chronic lymphocytic leukaemia

1 reference

12 December 2020

10.1371/JOURNAL.PMED.0050064

Identifiers

DOI

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18366248%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18366248%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

PubMed publication ID

18366248

2 references