N-epsilon-(carboxyethyl)lysine, a product of the chemical modification of proteins by methylglyoxal, increases with age in human lens proteins (Q28378989)

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English	N-epsilon-(carboxyethyl)lysine, a product of the chemical modification of proteins by methylglyoxal, increases with age in human lens proteins	scientific article

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scholarly article

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N-epsilon-(carboxyethyl)lysine, a product of the chemical modification of proteins by methylglyoxal, increases with age in human lens proteins (English)

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N(6)-(1-carboxyethyl)-L-lysine

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ChEBI release 2020-05-28

author name string

M U Ahmed

1

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E Brinkmann Frye

2

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T P Degenhardt

3

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S R Thorpe

4

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J W Baynes

5

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language of work or name

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publication date

1 June 1997

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Biochemical Journal

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324 ( Pt 2)

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565-70

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Carboxyethyllysine in a protein: native carbonyl reductase/NADP(+)-dependent prostaglandin dehydrogenase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1218467

20 March 2017

Reduction of trioses by NADPH-dependent aldo-keto reductases. Aldose reductase, methylglyoxal, and diabetic complications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1218467

20 March 2017

New biomarkers of Maillard reaction damage to proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1218467

29 September 2017

Role of the Maillard reaction in diabetes mellitus and diseases of aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1218467

29 September 2017

Accumulation of Maillard reaction products in skin collagen in diabetes and aging

1 reference

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29 September 2017

The glyoxalase system in health and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1218467

29 September 2017

Recent progress on the biologic and clinical significance of advanced glycosylation end products

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1218467

29 September 2017

Mechanism of autoxidative glycosylation: identification of glyoxal and arabinose as intermediates in the autoxidative modification of proteins by glucose

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1218467

29 September 2017

Spectroscopic studies of the protein-methylglyoxal adduct

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1218467

29 September 2017

A role of mixed-function oxidation reactions in the accumulation of altered enzyme forms during aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1218467

29 September 2017

Identification of fructose 3-phosphate in the lens of diabetic rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1218467

29 September 2017

Role of oxidative stress in development of complications in diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1218467

29 September 2017

High correlation between pentosidine protein crosslinks and pigmentation implicates ascorbate oxidation in human lens senescence and cataractogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1218467

29 September 2017

Modification of the glyoxalase system in human red blood cells by glucose in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1218467

2 June 2018

Aminoacetone oxidase from goat liver. Formation of methylglyoxal from aminoacetone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1218467

2 June 2018

Acetone metabolism in humans during diabetic ketoacidosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1218467

2 June 2018

The human red blood cell glyoxalase system in diabetes mellitus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1218467

2 June 2018

Role of oxygen in cross-linking and chemical modification of collagen by glucose

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1218467

2 June 2018

Anti-oxidant status in an in vitro model for hyperglycaemic lens cataract formation: competition for available nicotinamide adenine dinucleotide phosphate between glutathione reduction and the polyol pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1218467

2 June 2018

A convenient manual trinitrobenzenesulfonic acid method for monitoring amino acids and peptides in chromatographic column effluents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1218467

2 June 2018

Activities of aldose reductase, ATPases, and nucleotide concentrations of erythrocytes in patients with type 2 (non-insulin-dependent) diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/9182719

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of insulin on impaired antioxidant activities in aortic endothelial cells from diabetic rabbits

1 reference

https://pubmed.ncbi.nlm.nih.gov/9182719

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Control of sorbitol metabolism in renal inner medulla of diabetic rats: regulation by substrate, cosubstrate and products of the aldose reductase reaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/9182719

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidation of glycated proteins: age-dependent accumulation of N epsilon-(carboxymethyl)lysine in lens proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/9182719

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Age-dependent accumulation of N epsilon-(carboxymethyl)lysine and N epsilon-(carboxymethyl)hydroxylysine in human skin collagen

1 reference

https://pubmed.ncbi.nlm.nih.gov/9182719

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of diabetes and aging on carboxymethyllysine levels in human urine

1 reference

https://pubmed.ncbi.nlm.nih.gov/9182719

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kinetic parameters for the elimination reaction catalyzed by triosephosphate isomerase and an estimation of the reaction's physiological significance

1 reference

https://pubmed.ncbi.nlm.nih.gov/9182719

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein cross-linking by the Maillard reaction. Isolation, characterization, and in vivo detection of a lysine-lysine cross-link derived from methylglyoxal

1 reference

https://pubmed.ncbi.nlm.nih.gov/9182719

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glycation, glycoxidation, and cross-linking of collagen by glucose. Kinetics, mechanisms, and inhibition of late stages of the Maillard reaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/9182719

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormal glutathione metabolism and increased cytotoxicity caused by H2O2 in human umbilical vein endothelial cells cultured in high glucose medium

1 reference

https://pubmed.ncbi.nlm.nih.gov/9182719

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glyoxalase System in Clinical Diabetes Mellitus and Correlation with Diabetic Complications

1 reference

https://pubmed.ncbi.nlm.nih.gov/9182719

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Binding and modification of proteins by methylglyoxal under physiological conditions. A kinetic and mechanistic study with N alpha-acetylarginine, N alpha-acetylcysteine, and N alpha-acetyllysine, and bovine serum albumin

1 reference

https://pubmed.ncbi.nlm.nih.gov/9182719

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Weakened cellular scavenging activity against oxidative stress in diabetes mellitus: regulation of glutathione synthesis and efflux

1 reference

https://pubmed.ncbi.nlm.nih.gov/9182719

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolism of fructose-3-phosphate in the diabetic rat lens

1 reference

https://pubmed.ncbi.nlm.nih.gov/9182719

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired activation of glucose oxidation and NADPH supply in human endothelial cells exposed to H2O2 in high-glucose medium

1 reference

https://pubmed.ncbi.nlm.nih.gov/9182719

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of protein modification by glyoxal and glycolaldehyde, reactive intermediates of the Maillard reaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/9182719

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathways of Formation of Glycoxidation Products during Glycation of Collagen

1 reference

https://pubmed.ncbi.nlm.nih.gov/9182719

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detection of short-chain α-hydroxyaldehydic compounds as pentafluorbenzyloxime derivatives in bovine liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/9182719

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The advanced glycation end product, Nepsilon-(carboxymethyl)lysine, is a product of both lipid peroxidation and glycoxidation reactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/9182719

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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