Atherosclerosis and sterol 27-hydroxylase: evidence for a role of this enzyme in elimination of cholesterol from human macrophages (Q28369414)

2

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U Diczfalusy

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B Sevastik

4

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R J Xiu

5

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C Duan

6

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E Lund

Proceedings of the National Academy of Sciences of the United States of America

7

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language of work or name

English

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publication date

30 August 1994

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published in

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volume

91

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issue

18

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page(s)

8592-6

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cites work

Frameshift and splice-junction mutations in the sterol 27-hydroxylase gene cause cerebrotendinous xanthomatosis in Jews or Moroccan origin

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Sterol 27-hydroxylase in bile acid biosynthesis. Mechanism of oxidation of 5 beta-cholestane-3 alpha,7 alpha,12 alpha,27-tetrol into 3 alpha,7 alpha,12 alpha-trihydroxy-5 beta-cholestanoic acid

20 March 2017

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Identification of new mutations in sterol 27-hydroxylase gene in Japanese patients with cerebrotendinous xanthomatosis (CTX)

20 March 2017

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Cerebrotendinous xanthomatosis: a defect in mitochondrial 26-hydroxylation required for normal biosynthesis of cholic acid

20 March 2017

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

20 March 2017

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Bile Acid Synthesis in Man: Metabolism of 7α-Hydroxycholesterol-14C and 26-Hydroxycholesterol-3H

20 March 2017

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Cloning, structure, and expression of the mitochondrial cytochrome P-450 sterol 26-hydroxylase, a bile acid biosynthetic enzyme

20 March 2017

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Mutations in the bile acid biosynthetic enzyme sterol 27-hydroxylase underlie cerebrotendinous xanthomatosis

20 March 2017

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cDNA cloning of human oxysterol-binding protein and localization of the gene to human chromosome 11 and mouse chromosome 19

20 March 2017

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Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications

20 March 2017

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Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria

20 March 2017

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Role of the 26-hydroxylase in the biosynthesis of bile acids in the normal state and in cerebrotendinous xanthomatosis. An in vivo study

7 April 2017

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Rapid separation of lipid classes in high yield and purity using bonded phase columns

29 September 2017

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Demonstration of 26-hydroxylation of C27-steroids in human skin fibroblasts, and a deficiency of this activity in cerebrotendinous xanthomatosis

29 September 2017

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26-Hydroxycholesterol: synthesis, metabolism, and biologic activities

29 September 2017

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Mechanism of degradation of the steroid side chain in the formation of bile acids

29 September 2017

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Formation of 7 alpha- and 7 beta-hydroxylated bile acid precursors from 27-hydroxycholesterol in human liver microsomes and mitochondria

29 September 2017

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Selective inhibition of mitochondrial 27-hydroxylation of bile acid intermediates and 25-hydroxylation of vitamin D3 by cyclosporin A.

2 June 2018

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Sterol metabolism. 18. On the uniqueness of the occurrence of 26-hydroxycholesterol in the human aorta.

2 June 2018

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Characterization of a binding protein for the PCB metabolite 4,4'-bis(methylsulfonyl)-2,2',5,5'-tetrachlorobiphenyl present in bronchoalveolar lavage from healthy smokers and non-smokers

2 June 2018

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Purification of oxysterol binding protein from hamster liver cytosol

2 June 2018

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Evidence that 24- and 27-hydroxylation are not involved in the cholesterol-induced down-regulation of hydroxymethylglutaryl-CoA reductase in mouse liver

2 June 2018

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Cerebrotendinous xanthomatosis: reduced serum 26-hydroxycholesterol.

2 June 2018

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Squalene, 26-hydroxycholesterol and 7-ketocholesterol in human atheromatous plaques

27 November 2018

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12 December 2020

Cholestanol and 26-hydroxycholesterol in normal and atherosclerotic human aorta

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12 December 2020

Correlation between oxysterol binding to a cytosolic binding protein and potency in the repression of hydroxymethylglutaryl coenzyme A reductase

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12 December 2020

Occurrence of 3 beta-hydroxy-5-cholestenoic acid, 3 beta,7 alpha-dihydroxy-5-cholestenoic acid, and 7 alpha-hydroxy-3-oxo-4-cholestenoic acid as normal constituents in human blood

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12 December 2020

Evidence for the formation of 26-hydroxycholesterol by cytochrome P-450 in pig kidney mitochondria

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12 December 2020

Reconstitution of C27-steroid 26-hydroxylase activity from bovine brain mitochondria

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12 December 2020

Simultaneous quantification of several cholesterol autoxidation and monohydroxylation products by isotope-dilution mass spectrometry

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12 December 2020

7 alpha-hydroxylation of 27-hydroxycholesterol in human liver microsomes

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12 December 2020

Identifiers

DOI

10.1073/PNAS.91.18.8592

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ADS bibcode

1994PNAS...91.8592B

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1 reference

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PubMed publication ID

8078928

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