Regulation of regional expression in rat brain PC2 by thyroid hormone/characterization of novel negative thyroid hormone response elements in the PC2 promoter (Q28297247)

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English	Regulation of regional expression in rat brain PC2 by thyroid hormone/characterization of novel negative thyroid hormone response elements in the PC2 promoter	scientific article

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scholarly article

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Regulation of regional expression in rat brain PC2 by thyroid hormone/characterization of novel negative thyroid hormone response elements in the PC2 promoter (English)

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author name string

Xiaoxiong Shen

1

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Qiao-Ling Li

2

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Gregory A Brent

3

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Theodore C Friedman

4

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language of work or name

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publication date

January 2005

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American Journal of Physiology - Endocrinology and Metabolism

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288

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1

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E236-45

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Defective prodynorphin processing in mice lacking prohormone convertase PC2.

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Action of thyroid hormone in brain

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Coordinate regulation of mRNA levels of pro-opiomelanocortin and the candidate processing enzymes PC2 and PC3, but not furin, in rat pituitary intermediate lobe

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Prohormone-converting enzymes: regulation and evaluation of function using antisense RNA.

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Effects of varying the position of thyroid hormone response elements within the rat growth hormone promoter: implications for positive and negative regulation by 3,5,3'-triiodothyronine

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Processing of pro-opiomelanocortin in GH3 cells: inhibition by prohormone convertase 2 (PC2) antisense mRNA.

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Defective prohormone processing and altered pancreatic islet morphology in mice lacking active SPC2.

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Isolation of two complementary deoxyribonucleic acid clones from a rat insulinoma cell line based on similarities to Kex2 and furin sequences and the specific localization of each transcript to endocrine and neuroendocrine tissues in rats

1 reference

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Transactivation by the thyroid hormone receptor is dependent on the spacer sequence in hormone response elements containing directly repeated half-sites

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Identification of a thyroid hormone receptor that is pituitary-specific

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Obesity and impaired prohormone processing associated with mutations in the human prohormone convertase 1 gene

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Neuroendocrine-specific expression of the human prohormone convertase 1 gene. Hormonal regulation of transcription through distinct cAMP response elements

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PACE4: a subtilisin-like endoprotease prevalent in the anterior pituitary and regulated by thyroid status

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Biosynthesis of proopiomelanocortin-derived peptides in prohormone convertase 2 and 7B2 null mice

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Regulation of the human trh (htrh) gene by human thyroid hormone receptor β1 (hTRβ1) mutants

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Regulation of prohormone convertase 1 (PC1) by thyroid hormone

1 reference

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Regulation of prohormone convertase 1 (PC1) by gp130-related cytokines

1 reference

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

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The neuroendocrine polypeptide 7B2 is an endogenous inhibitor of prohormone convertase PC2

1 reference

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Heterodimerization preferences of thyroid hormone receptor alpha isoforms.

1 reference

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Regulation of pancreatic PC1 and PC2 associated with increased glucagon-like peptide 1 in diabetic rats

1 reference

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Molecular Basis of Thyroid Hormone-Dependent Brain Development*

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Brief report: impaired processing of prohormones associated with abnormalities of glucose homeostasis and adrenal function

1 reference

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Thyroid Hormone Regulation of Peptidylglycine α-Amidating Monooxygenase Expression in Anterior Pituitary Gland

1 reference

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Negative regulation of the gene for the preprothyrotropin-releasing hormone from the mouse by thyroid hormone requires additional factors in conjunction with thyroid hormone receptors

1 reference

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Targeted disruption of the type 2 selenodeiodinase gene (DIO2) results in a phenotype of pituitary resistance to T4

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Pro-protein convertases of subtilisin/kexin family.

1 reference

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Proprotein and prohormone convertases: a family of subtilases generating diverse bioactive polypeptides

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The family of subtilisin/kexin like pro-protein and pro-hormone convertases: divergent or shared functions

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cDNA sequence of two distinct pituitary proteins homologous to Kex2 and furin gene products: tissue-specific mRNAs encoding candidates for pro-hormone processing proteinases

1 reference

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Cloning and primary sequence of a mouse candidate prohormone convertase PC1 homologous to PC2, Furin, and Kex2: distinct chromosomal localization and messenger RNA distribution in brain and pituitary compared to PC2.

1 reference

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Thyroid hormone regulation of prohormone convertase 1 (PC1): regional expression in rat brain and in vitro characterization of negative thyroid hormone response elements

1 reference

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Thyroid hormone receptor DNA binding is required for both positive and negative gene regulation

1 reference

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The proprotein convertases

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Thyroid hormone response elements differentially modulate the interactions of thyroid hormone receptors with two receptor binding domains in the steroid receptor coactivator-1.

1 reference

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A Novel Retinoid X Receptor-Independent Thyroid Hormone Response Element Is Present in the Human Type 1 Deiodinase Gene

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The prohormone convertase enzyme 2 (PC2) is essential for processing pro-islet amyloid polypeptide at the NH2-terminal cleavage site

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Development and validation of real-time quantitative reverse transcriptase-polymerase chain reaction for monitoring gene expression in cardiac myocytes in vitro

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Severe block in processing of proinsulin to insulin accompanied by elevation of des-64,65 proinsulin intermediates in islets of mice lacking prohormone convertase 1/3.

1 reference

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Disruption of PC1/3 expression in mice causes dwarfism and multiple neuroendocrine peptide processing defects

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Identifiers

10.1152/AJPENDO.00144.2004

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