Structure and function of splice variants of the cardiac voltage-gated sodium channel Na(v)1.5 (Q28279905)

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31 January 2020

review article

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title

Structure and function of splice variants of the cardiac voltage-gated sodium channel Na(v)1.5. (English)

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31 January 2020

author name string

Annett Schroeter

1

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31 January 2020

Stefan Walzik

2

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31 January 2020

Steve Blechschmidt

3

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31 January 2020

Volker Haufe

4

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31 January 2020

Thomas Zimmer

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language of work or name

English

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publication date

14 April 2010

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Journal of Molecular and Cellular Cardiology

31 January 2020

published in

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volume

49

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issue

1

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31 January 2020

page(s)

16-24

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From ionic currents to molecular mechanisms: the structure and function of voltage-gated sodium channels

31 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

Primary structure and functional expression of the human cardiac tetrodotoxin-insensitive voltage-dependent sodium channel

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

Voltage-gated Na+ channel transcript patterns in the mammalian heart are species-dependent

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

SCN5A channelopathies--an update on mutations and mechanisms

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

Human heart failure is associated with abnormal C-terminal splicing variants in the cardiac sodium channel

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

Tandem promoters and developmentally regulated 5'- and 3'-mRNA untranslated regions of the mouse Scn5a cardiac sodium channel

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

Haploinsufficiency in combination with aging causes SCN5A-linked hereditary Lenègre disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

Cryptic 5' splice site activation in SCN5A associated with Brugada syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

Identification of a novel voltage-gated Na+ channel rNa(v)1.5a in the rat hippocampal progenitor stem cell line HiB5.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

Mouse heart Na+ channels: primary structure and function of two isoforms and alternatively spliced variants

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

Modulation of Nav1.5 channel function by an alternatively spliced sequence in the DII/DIII linker region.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

Expression pattern of neuronal and skeletal muscle voltage-gated Na+ channels in the developing mouse heart

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

Novel isoforms of the sodium channels Nav1.8 and Nav1.5 are produced by a conserved mechanism in mouse and rat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

The sodium channel Nav1.5a is the predominant isoform expressed in adult mouse dorsal root ganglia and exhibits distinct inactivation properties from the full-length Nav1.5 channel.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

Tetrodotoxin-resistant Na+ channels in human neuroblastoma cells are encoded by new variants of Nav1.5/SCN5A.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

Specific properties of sodium currents in multipotent striatal progenitor cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

Analysis of four novel variants of Nav1.5/SCN5A cloned from the brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

Cardiac sodium channel Na(v)1.5 and interacting proteins: Physiology and pathophysiology

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

A ubiquitous splice variant and a common polymorphism affect heterologous expression of recombinant human SCN5A heart sodium channels

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

Common human SCN5A polymorphisms have altered electrophysiology when expressed in Q1077 splice variants

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

Partial expression defect for the SCN5A missense mutation G1406R depends on splice variant background Q1077 and rescue by mexiletine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

Cardiac sodium channel dysfunction in sudden infant death syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

Reverse transcriptase template switching and false alternative transcripts.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

When good transcripts go bad: artifactual RT-PCR 'splicing' and genome analysis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

Voltage-gated sodium channel expression and potentiation of human breast cancer metastasis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

Evolutionary convergence of alternative splicing in ion channels

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

Developmentally regulated alternative RNA splicing of rat brain sodium channel mRNAs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

A novel polyclonal antibody specific for the Na(v)1.5 voltage-gated Na(+) channel 'neonatal' splice form

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

Molecular cloning of a putative tetrodotoxin-resistant rat heart Na+ channel isoform

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

Involvement of a novel fast inward sodium current in the invasion capacity of a breast cancer cell line

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

The neonatal splice variant of Nav1.5 potentiates in vitro invasive behaviour of MDA-MB-231 human breast cancer cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

An emerging role for voltage-gated Na+ channels in cellular migration: regulation of central nervous system development and potentiation of invasive cancers

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

Alternative splicing of Nav1.5: an electrophysiological comparison of 'neonatal' and 'adult' isoforms and critical involvement of a lysine residue.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

Contribution of neuronal sodium channels to the cardiac fast sodium current INa is greater in dog heart Purkinje fibers than in ventricles

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

The tail of the cardiac sodium channel

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

Molecular diversity of voltage-gated sodium channel alpha and beta subunit mRNAs in human tissues

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

Localization of Nav1.5 sodium channel protein in the mouse brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

Selective localization of cardiac SCN5A sodium channels in limbic regions of rat brain.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

The cardiac sodium channel mRNA is expressed in the developing and adult rat and human brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

Glial cells have heart: rH1 Na+ channel mRNA and protein in spinal cord astrocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

SCN5A is expressed in human jejunal circular smooth muscle cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

Sodium current in human jejunal circular smooth muscle cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

Functional expression of "cardiac-type" Nav1.5 sodium channel in canine intracardiac ganglia.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

Functional and Molecular Characterization of Voltage-Gated Sodium Channels in Uteri from Nonpregnant Rats1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

A mutation in telethonin alters Nav1.5 function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

Brain and heart sodium channel subtype mRNA expression in rat cerebral cortex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

A heart-like Na+ current in the medial entorhinal cortex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

A tetrodotoxin-insensitive [corrected] sodium current initiates burst firing of neocortical neurons

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

A novel tetrodotoxin-insensitive, slow sodium current in striatal and hippocampal neurons

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

New SCN5A mutation in a SUDEP victim with idiopathic epilepsy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

Neonatal seizures and long QT syndrome: a cardiocerebral channelopathy?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

Expression of alternatively spliced sodium channel alpha-subunit genes. Unique splicing patterns are observed in dorsal root ganglia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

A catalog of SCN1A variants

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

Expression profiles of voltage-gated Na(+) channel alpha-subunit genes in rat and human prostate cancer cell lines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

T-lymphocyte invasiveness: control by voltage-gated Na+ channel activity.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

Neuronal characteristics of small-cell lung cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

Voltage-gated Na+ channels confer invasive properties on human prostate cancer cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

Voltage-gated sodium channels: new targets in cancer therapy?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

Voltage-gated sodium channels potentiate the invasive capacities of human non-small-cell lung cancer cell lines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

Voltage-gated Sodium Channel Activity Promotes Cysteine Cathepsin-dependent Invasiveness and Colony Growth of Human Cancer Cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

A novel adhesion molecule in human breast cancer cells: voltage-gated Na+ channel beta1 subunit.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

Calcium-dependent regulation of the voltage-gated sodium channel hH1: intrinsic and extrinsic sensors use a common molecular switch

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

Secondary structure of the human cardiac Na+ channel C terminus: evidence for a role of helical structures in modulation of channel inactivation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

An EF-hand in the sodium channel couples intracellular calcium to cardiac excitability

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

Solution NMR structure of the C-terminal EF-hand domain of human cardiac sodium channel NaV1.5

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

Genomic organization of the human SCN5A gene encoding the cardiac sodium channel

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

Combination of cardiac conduction disease and long QT syndrome caused by mutation T1620K in the cardiac sodium channel

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

Differential modulation of late sodium current by protein kinase A in R1623Q mutant of LQT3.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.04.004

10.1016/J.YJMCC.2010.04.004

7 January 2021

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31 January 2020

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