Cracking the control of RNA polymerase II elongation by 7SK snRNP and P-TEFb (Q28276848)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27369380%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

review article

1 reference

title

Cracking the control of RNA polymerase II elongation by 7SK snRNP and P-TEFb (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27369380%20AND%20SRC:MED&resulttype=core&format=json

RNA nucleotidyltransferases

17 March 2020

main subject

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1 August 2019

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28 September 2019

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28 November 2019

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20 December 2019

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22 December 2019

2

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17 March 2020

author name string

Alexandre J C Quaresma

series ordinal

1

1 reference

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17 March 2020

Matjaz Barboric

series ordinal

3

1 reference

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17 March 2020

language of work or name

English

0 references

publication date

1 July 2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27369380%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

published in

Nucleic Acids Research

6 references

1 August 2019

28 September 2019

28 November 2019

20 December 2019

22 December 2019

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17 March 2020

volume

44

1 reference

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17 March 2020

issue

16

1 reference

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17 March 2020

page(s)

7527-7539

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Creative Commons Attribution-NonCommercial 4.0 International

17 March 2020

copyright license

5 references

1 August 2019

28 September 2019

28 November 2019

20 December 2019

Getting up to speed with transcription elongation by RNA polymerase II

22 December 2019

cites work

1 reference

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Convergent transcription at intragenic super-enhancers targets AID-initiated genomic instability

20 March 2017

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RNA helicase DDX21 coordinates transcription and ribosomal RNA processing

20 March 2017

1 reference

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Brd4 activates P-TEFb for RNA polymerase II CTD phosphorylation

20 March 2017

1 reference

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Brd4 and JMJD6-associated anti-pause enhancers in regulation of transcriptional pause release

20 March 2017

1 reference

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Structure and dynamics of a stabilized coiled-coil domain in the P-TEFb regulator Hexim1

20 March 2017

1 reference

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Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia

20 March 2017

1 reference

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Human mediator subunit MED26 functions as a docking site for transcription elongation factors

20 March 2017

1 reference

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The super elongation complex (SEC) and MLL in development and disease

20 March 2017

1 reference

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Selective inhibition of BET bromodomains

20 March 2017

1 reference

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The mechanism of release of P-TEFb and HEXIM1 from the 7SK snRNP by viral and cellular activators includes a conformational change in 7SK

20 March 2017

1 reference

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TIF1gamma controls erythroid cell fate by regulating transcription elongation

20 March 2017

1 reference

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c-Myc regulates transcriptional pause release

20 March 2017

1 reference

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Acetylation of cyclin T1 regulates the equilibrium between active and inactive P-TEFb in cells

20 March 2017

1 reference

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20 March 2017

1 reference

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LARP7 is a stable component of the 7SK snRNP while P-TEFb, HEXIM1 and hnRNP A1 are reversibly associated

20 March 2017

1 reference

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20 March 2017

1 reference

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Structure of the Cyclin T binding domain of Hexim1 and molecular basis for its recognition of P-TEFb

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5027500

Conserved P-TEFb-interacting domain of BRD4 inhibits HIV transcription

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5027500

Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5027500

Oligomerization of HEXIM1 via 7SK snRNA and coiled-coil region directs the inhibition of P-TEFb

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5027500

Recruitment of P-TEFb for stimulation of transcriptional elongation by the bromodomain protein Brd4

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5027500

The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5027500

Analysis of the large inactive P-TEFb complex indicates that it contains one 7SK molecule, a dimer of HEXIM1 or HEXIM2, and two P-TEFb molecules containing Cdk9 phosphorylated at threonine 186

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5027500

Identification of a cyclin T-binding domain in Hexim1 and biochemical analysis of its binding competition with HIV-1 Tat

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5027500

Compensatory contributions of HEXIM1 and HEXIM2 in maintaining the balance of active and inactive positive transcription elongation factor b complexes for control of transcription

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5027500

Binding of the 7SK snRNA turns the HEXIM1 protein into a P-TEFb (CDK9/cyclin T) inhibitor

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5027500

A human immunodeficiency virus type 1 Tat-like arginine-rich RNA-binding domain is essential for HEXIM1 to inhibit RNA polymerase II transcription through 7SK snRNA-mediated inactivation of P-TEFb

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5027500

Inhibition of P-TEFb (CDK9/Cyclin T) kinase and RNA polymerase II transcription by the coordinated actions of HEXIM1 and 7SK snRNA

20 March 2017

1 reference

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MAQ1 and 7SK RNA interact with CDK9/cyclin T complexes in a transcription-dependent manner

20 March 2017

1 reference

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7SK small nuclear RNA binds to and inhibits the activity of CDK9/cyclin T complexes

20 March 2017

1 reference

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The 7SK small nuclear RNA inhibits the CDK9/cyclin T1 kinase to control transcription

20 March 2017

1 reference

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Purification, characterization, and cloning of the cDNA of human signal recognition particle RNA 3'-adenylating enzyme

20 March 2017

1 reference

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Tat competes with CIITA for the binding to P-TEFb and blocks the expression of MHC class II genes in HIV infection

20 March 2017

1 reference

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NELF, a multisubunit complex containing RD, cooperates with DSIF to repress RNA polymerase II elongation

20 March 2017

1 reference

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Evidence that P-TEFb alleviates the negative effect of DSIF on RNA polymerase II-dependent transcription in vitro

20 March 2017

1 reference

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A novel CDK9-associated C-type cyclin interacts directly with HIV-1 Tat and mediates its high-affinity, loop-specific binding to TAR RNA

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5027500

DSIF, a novel transcription elongation factor that regulates RNA polymerase II processivity, is composed of human Spt4 and Spt5 homologs

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5027500

P-TEFb kinase is required for HIV Tat transcriptional activation in vivo and in vitro

20 March 2017

1 reference

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Structural analyses of the 7SK ribonucleoprotein (RNP), the most abundant human small RNP of unknown function

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5027500

SR proteins collaborate with 7SK and promoter-associated nascent RNA to release paused polymerase

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5027500

Misguided transcriptional elongation causes mixed lineage leukemia

20 March 2017

1 reference

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Conserved and divergent features of the structure and function of La and La-related proteins (LARPs)

20 March 2017

1 reference

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Dynamics of human immunodeficiency virus transcription: P-TEFb phosphorylates RD and dissociates negative effectors from the transactivation response element

20 March 2017

1 reference

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Promoter-proximal pausing of RNA polymerase II: emerging roles in metazoans

20 March 2017

1 reference

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Anti-termination of transcription within the long terminal repeat of HIV-1 by tat gene product

7 April 2017

1 reference

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P-TEFb, a cyclin-dependent kinase controlling elongation by RNA polymerase II

7 April 2017

1 reference

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Stress from Nucleotide Depletion Activates the Transcriptional Regulator HEXIM1 to Suppress Melanoma.

7 April 2017

1 reference

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7SK-BAF axis controls pervasive transcription at enhancers

29 September 2017

1 reference

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Heptad-Specific Phosphorylation of RNA Polymerase II CTD.

29 September 2017

1 reference

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P-TEFb regulation of transcription termination factor Xrn2 revealed by a chemical genetic screen for Cdk9 substrates.

29 September 2017

1 reference

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KAP1 Recruitment of the 7SK snRNP Complex to Promoters Enables Transcription Elongation by RNA Polymerase II.

29 September 2017

1 reference

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RNA polymerase II-associated factor 1 regulates the release and phosphorylation of paused RNA polymerase II.

29 September 2017

1 reference

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PPM1G Binds 7SK RNA and Hexim1 To Block P-TEFb Assembly into the 7SK snRNP and Sustain Transcription Elongation.

29 September 2017

1 reference

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Native elongating transcript sequencing reveals human transcriptional activity at nucleotide resolution

29 September 2017

1 reference

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Phosphorylation of HEXIM1 at Tyr271 and Tyr274 Promotes Release of P-TEFb from the 7SK snRNP Complex and Enhances Proviral HIV Gene Expression

29 September 2017

1 reference

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CDK9 inhibitors define elongation checkpoints at both ends of RNA polymerase II-transcribed genes.

29 September 2017

1 reference

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Structural insight into the mechanism of stabilization of the 7SK small nuclear RNA by LARP7.

29 September 2017

1 reference

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Suppression of pervasive noncoding transcription in embryonic stem cells by esBAF.

29 September 2017

1 reference

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Characterization of human cyclin-dependent kinase 12 (CDK12) and CDK13 complexes in C-terminal domain phosphorylation, gene transcription, and RNA processing

29 September 2017

1 reference

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Integrator regulates transcriptional initiation and pause release following activation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5027500

TRIM28 regulates RNA polymerase II promoter-proximal pausing and pause release

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5027500

LARP7 suppresses P-TEFb activity to inhibit breast cancer progression and metastasis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5027500

HMGA1 recruits CTIP2-repressed P-TEFb to the HIV-1 and cellular target promoters

29 September 2017

1 reference

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Coupling mRNA processing with transcription in time and space.

29 September 2017

1 reference

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Calpain 2 activation of P-TEFb drives megakaryocyte morphogenesis and is disrupted by leukemogenic GATA1 mutation

29 September 2017

1 reference

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AFF1 is a ubiquitous P-TEFb partner to enable Tat extraction of P-TEFb from 7SK snRNP and formation of SECs for HIV transactivation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5027500

The non-coding snRNA 7SK controls transcriptional termination, poising, and bidirectionality in embryonic stem cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5027500

RNA polymerase II transcription elongation control

29 September 2017

1 reference

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CTIP2 is a negative regulator of P-TEFb

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5027500

Viral-host interactions that control HIV-1 transcriptional elongation

29 September 2017

1 reference

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RNA elements directing in vivo assembly of the 7SK/MePCE/Larp7 transcriptional regulatory snRNP.

29 September 2017

1 reference

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PKC phosphorylates HEXIM1 and regulates P-TEFb activity.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5027500

RNA polymerase II elongation control

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5027500

Human Polymerase-Associated Factor complex (PAFc) connects the Super Elongation Complex (SEC) to RNA polymerase II on chromatin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5027500

T-cell receptor signaling enhances transcriptional elongation from latent HIV proviruses by activating P-TEFb through an ERK-dependent pathway

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5027500

KAP1 protein: an enigmatic master regulator of the genome

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5027500

Cap-binding Protein Complex Links Pre-mRNA Capping to Transcription Elongation and Alternative Splicing through Positive Transcription Elongation Factor b (P-TEFb)

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5027500

Protein Phosphatase-1 Activates CDK9 by Dephosphorylating Ser175

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5027500

Expression of a protein phosphatase 1 inhibitor, cdNIPP1, increases CDK9 threonine 186 phosphorylation and inhibits HIV-1 transcription

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5027500

Controlling cellular P-TEFb activity by the HIV-1 transcriptional transactivator Tat

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5027500

Human T-Lymphotropic Virus Type 1 Tax Protein Complexes with P-TEFb and Competes for Brd4 and 7SK snRNP/HEXIM1 Binding

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5027500

HIV-1 Tat assembles a multifunctional transcription elongation complex and stably associates with the 7SK snRNP

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5027500

HIV-1 Tat and host AFF4 recruit two transcription elongation factors into a bifunctional complex for coordinated activation of HIV-1 transcription

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5027500

P-TEFb stimulates transcription elongation and pre-mRNA splicing through multilateral mechanisms

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5027500

AFF4, a component of the ELL/P-TEFb elongation complex and a shared subunit of MLL chimeras, can link transcription elongation to leukemia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5027500

A capping-independent function of MePCE in stabilizing 7SK snRNA and facilitating the assembly of 7SK snRNP.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5027500

Control of inducible gene expression by signal-dependent transcriptional elongation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5027500

7SK snRNP/P-TEFb couples transcription elongation with alternative splicing and is essential for vertebrate development

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5027500

PP2B and PP1alpha cooperatively disrupt 7SK snRNP to release P-TEFb for transcription in response to Ca2+ signaling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5027500

HMBA releases P-TEFb from HEXIM1 and 7SK snRNA via PI3K/Akt and activates HIV transcription

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5027500

Inhibition of HIV-1 replication by P-TEFb inhibitors DRB, seliciclib and flavopiridol correlates with release of free P-TEFb from the large, inactive form of the complex

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5027500

SR proteins function in coupling RNAP II transcription to pre-mRNA splicing.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5027500

Manipulation of P-TEFb control machinery by HIV: recruitment of P-TEFb from the large form by Tat and binding of HEXIM1 to TAR.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5027500

Tat competes with HEXIM1 to increase the active pool of P-TEFb for HIV-1 transcription.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5027500

Tax interacts with P-TEFb in a novel manner to stimulate human T-lymphotropic virus type 1 transcription

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5027500

Gene-specific requirement for P-TEFb activity and RNA polymerase II phosphorylation within the p53 transcriptional program

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5027500

Nuclear targeting of protein phosphatase-1 by HIV-1 Tat protein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5027500

Methylphosphate cap structure in small RNAs reduces the affinity of RNAs to La protein.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5027500

Activation and function of cyclin T-Cdk9 (positive transcription elongation factor-b) in cardiac muscle-cell hypertrophy.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5027500

CDK-9/cyclin T (P-TEFb) is required in two postinitiation pathways for transcription in the C. elegans embryo

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5027500

3' end formation of pre-mRNA and phosphorylation of Ser2 on the RNA polymerase II CTD are reciprocally coupled in human cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5027500

Transcription factors mediate the enzymatic disassembly of promoter-bound 7SK snRNP to locally recruit P-TEFb for transcription elongation.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5027500

RNA-mediated displacement of an inhibitory snRNP complex activates transcription elongation

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5027500

DSIF, the Paf1 complex, and Tat-SF1 have nonredundant, cooperative roles in RNA polymerase II elongation

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5027500

Dynamic remodelling of human 7SK snRNP controls the nuclear level of active P-TEFb

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5027500

NF-kappaB binds P-TEFb to stimulate transcriptional elongation by RNA polymerase II.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5027500

Transcriptional pausing at +62 of the HIV-1 nascent RNA modulates formation of the TAR RNA structure

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5027500

Purification of P-TEFb, a transcription factor required for the transition into productive elongation.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5027500

The RNA polymerase II molecule at the 5' end of the uninduced hsp70 gene of D. melanogaster is transcriptionally engaged.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5027500

Hold back of RNA polymerase II at the transcription start site mediates down-regulation of c-myc in vivo

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5027500

The block to transcriptional elongation within the human c-myc gene is determined in the promoter-proximal region

2 June 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKW585

Recruitment of P-TEFb (Cdk9-Pch1) to chromatin by the cap-methyl transferase Pcm1 in fission yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKW585

Coordination of transcription, RNA processing, and surveillance by P-TEFb kinase on heat shock genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKW585

The yeast cap binding complex modulates transcription factor recruitment and establishes proper histone H3K36 trimethylation during active transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKW585

Evolution of 7SK RNA and its protein partners in metazoa

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKW585

Interplay between 7SK snRNA and oppositely charged regions in HEXIM1 direct the inhibition of P-TEFb

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKW585

Phosphorylated positive transcription elongation factor b (P-TEFb) is tagged for inhibition through association with 7SK snRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKW585

The transcription-dependent dissociation of P-TEFb-HEXIM1-7SK RNA relies upon formation of hnRNP-7SK RNA complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKW585

Biogeography of the ecosystems of the healthy human body

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKW585

Kick-sTARting HIV-1 transcription elongation by 7SK snRNP deporTATion

21 January 2018

1 reference

12 December 2020

Association between the 7 S RNA and the lupus La protein varies among cell types

1 reference

12 December 2020

Adenylation of small RNAs in human cells. Development of a cell-free system for accurate adenylation on the 3'-end of human signal recognition particle RNA

1 reference

12 December 2020

Serine-7 but not serine-5 phosphorylation primes RNA polymerase II CTD for P-TEFb recognition

1 reference

12 December 2020

Identifiers

DOI

10.1093/NAR/GKW585

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27369380%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27369380%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

PubMed publication ID

27369380

2 references