IL-17A is essential for cell activation and inflammatory gene circuits in subjects with psoriasis (Q28268370)

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object named as

James G Krueger

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author name string

Scott Fretzin

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Patrick A Haslett

4

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Krista M Phipps

5

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Gregory S Cameron

6

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Juliet McColm

7

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Artemis Katcherian

8

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Inna Cueto

9

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Traci White

10

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Subhashis Banerjee

11

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Robert W Hoffman

The Journal of Allergy and Clinical Immunology

12

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language of work or name

English

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publication date

July 2012

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published in

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volume

130

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issue

1

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page(s)

145-54.e9

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describes a project that uses

limma

1 reference

Europe PubMed Central

22 June 2022

https://europepmc.org/article/PMC/3470466

inferred from PubMed Central ID database lookup

cites work

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Effective narrow-band UVB radiation therapy suppresses the IL-23/IL-17 axis in normalized psoriasis plaques

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Effective treatment of psoriasis with etanercept is linked to suppression of IL-17 signaling, not immediate response TNF genes

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IL-22-producing "T22" T cells account for upregulated IL-22 in atopic dermatitis despite reduced IL-17-producing TH17 T cells

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IL-22 is required for Th17 cell-mediated pathology in a mouse model of psoriasis-like skin inflammation

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29 September 2017

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Phagocytosis of apoptotic neutrophils regulates granulopoiesis via IL-23 and IL-17.

29 September 2017

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IL-22 inhibits epidermal differentiation and induces proinflammatory gene expression and migration of human keratinocytes

29 September 2017

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Alefacept reduces infiltrating T cells, activated dendritic cells, and inflammatory genes in psoriasis vulgaris

29 September 2017

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Novel mechanisms of T-cell and dendritic cell activation revealed by profiling of psoriasis on the 63,100-element oligonucleotide array

29 September 2017

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29 September 2017

Treatment of psoriasis

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Psoriasis is characterized by accumulation of immunostimulatory and Th1/Th17 cell-polarizing myeloid dendritic cells

29 September 2017

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2 June 2018

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Sequence variants in the genes for the interleukin-23 receptor (IL23R) and its ligand (IL12B) confer protection against psoriasis.

27 November 2018

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In vitro and in situ expression of IL-23 by keratinocytes in healthy skin and psoriasis lesions: enhanced expression in psoriatic skin

27 November 2018

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IL-17 markedly up-regulates beta-defensin-2 expression in human airway epithelium via JAK and NF-kappaB signaling pathways

27 November 2018

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Anti–Interleukin-17 Monoclonal Antibody Ixekizumab in Chronic Plaque Psoriasis

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12 December 2020

A global phase III randomized controlled trial of etanercept in psoriasis: safety, efficacy, and effect of dose reduction

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IL-22 regulates the expression of genes responsible for antimicrobial defense, cellular differentiation, and mobility in keratinocytes: a potential role in psoriasis

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The Effects of IL-20 Subfamily Cytokines on Reconstituted Human Epidermis Suggest Potential Roles in Cutaneous Innate Defense and Pathogenic Adaptive Immunity in Psoriasis

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Identification of Cellular Pathways of "Type 1," Th17 T Cells, and TNF- and Inducible Nitric Oxide Synthase-Producing Dendritic Cells in Autoimmune Inflammation through Pharmacogenomic Study of Cyclosporine A in Psoriasis

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Psoriasis Vulgaris Lesions Contain Discrete Populations of Th1 and Th17 T Cells

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12 December 2020

Efficacy and safety results from a phase III, randomized controlled trial comparing the safety and efficacy of briakinumab with etanercept and placebo in patients with moderate to severe chronic plaque psoriasis

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