NUMB controls p53 tumour suppressor activity (Q28263413)

8

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Daniela Tosoni

2

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Viviana Galimberti

5

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Paolo Nuciforo

object named as

Paolo Nuciforo

3

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Giuseppe Viale

6

object named as

Giuseppe Viale

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author name string

Ivan N Colaluca

1

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Francesca Senic-Matuglia

4

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Salvatore Pece

Asymmetric cell division.

7

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language of work or name

English

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publication date

3 January 2008

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published in

Nature

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volume

451

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issue

7174

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page(s)

76-80

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cites work

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06412

7 January 2021

Numb is an endocytic protein

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06412

7 January 2021

The endocytic protein alpha-Adaptin is required for numb-mediated asymmetric cell division in Drosophila

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06412

7 January 2021

Numb and alpha-Adaptin regulate Sanpodo endocytosis to specify cell fate in Drosophila external sensory organs

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06412

7 January 2021

Loss of negative regulation by Numb over Notch is relevant to human breast carcinogenesis

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06412

7 January 2021

p53 mutations in human cancers

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06412

7 January 2021

The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06412

7 January 2021

Mdm2 promotes the rapid degradation of p53

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06412

7 January 2021

Regulation of p53 stability by Mdm2

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06412

7 January 2021

ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06412

7 January 2021

Amplification of a gene encoding a p53-associated protein in human sarcomas

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06412

7 January 2021

Tumor surveillance via the ARF-p53 pathway.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06412

7 January 2021

Amplification of the MDM2 gene in human breast cancer and its association with MDM2 and p53 protein status.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06412

7 January 2021

Somatic mutations in the p53 gene and prognosis in breast cancer: a meta-analysis

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06412

7 January 2021

p14ARF expression in invasive breast cancers and ductal carcinoma in situ--relationships to p53 and Hdm2

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06412

7 January 2021

The INK4A/ARF locus and its two gene products

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06412

7 January 2021

Analysis of genetic and epigenetic processes that influence p14ARF expression in breast cancer

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06412

7 January 2021

Concomitant expression of p16INK4a and p14ARF in primary breast cancer and analysis of inactivation mechanisms.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06412

7 January 2021

The Mdm2 oncoprotein interacts with the cell fate regulator Numb

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06412

7 January 2021

In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06412

7 January 2021

DNA Double-stranded Breaks Induce Histone H2AX Phosphorylation on Serine 139

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06412

7 January 2021

A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06412

7 January 2021

Negative regulation of dE2F1 by cyclin-dependent kinases controls cell cycle timing

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06412

7 January 2021

p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06412

7 January 2021

Evidence that dynamin-2 functions as a signal-transducing GTPase

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06412

7 January 2021

Requirement of clathrin heavy chain for p53-mediated transcription

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06412

7 January 2021

Telomeres, stem cells, senescence, and cancer

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06412

7 January 2021

Expression of the wild-type p53 antioncogene induces guanine nucleotide-dependent stem cell division kinetics

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06412

7 January 2021

Immortal DNA strand cosegregation requires p53/IMPDH-dependent asymmetric self-renewal associated with adult stem cells

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06412

7 January 2021

A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06412

7 January 2021

Molecular mechanisms of coupled monoubiquitination

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06412

7 January 2021

A Randomized Comparison of Sentinel-Node Biopsy with Routine Axillary Dissection in Breast Cancer

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06412

7 January 2021