The neurobiology of itch (Q28247676)

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25 December 2019

review article

1 reference

title

The neurobiology of itch (English)

1 reference

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25 December 2019

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2

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25 December 2019

Sonja Ständer

series ordinal

3

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25 December 2019

Martin Schmelz

series ordinal

5

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25 December 2019

4

Gil Yosipovitch

1 reference

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25 December 2019

author name string

Akihiko Ikoma

series ordinal

1

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25 December 2019

language of work or name

English

0 references

publication date

1 July 2006

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Nature Reviews Neuroscience

25 December 2019

published in

1 reference

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25 December 2019

volume

7

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25 December 2019

issue

7

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25 December 2019

page(s)

535-547

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Neural mechanisms of cutaneous nociceptive pain

25 December 2019

cites work

1 reference

The Enteric Nervous System in Inflammation and Pain: The Role of Proteinase-Activated Receptors

21 January 2018

1 reference

A hot new twist to hair biology: involvement of vanilloid receptor-1 (VR1/TRPV1) signaling in human hair growth control

21 January 2018

1 reference

AG-3–5: a chemical producing sensations of cold

21 January 2018

1 reference

How do you feel? Interoception: the sense of the physiological condition of the body

21 January 2018

1 reference

Opioid modulation of scratching and spinal c-fos expression evoked by intradermal serotonin.

21 January 2018

1 reference

Specific C-Receptors for Itch in Human Skin

31 March 2020

1 reference

Spinothalamic lamina I neurons selectively sensitive to histamine: a central neural pathway for itch

31 March 2020

1 reference

Itching for an explanation

31 March 2020

1 reference

Itch: scratching more than the surface

31 March 2020

1 reference

Itch and pruritus: what are they, and how should itches be classified?

31 March 2020

1 reference

A comparison of the effects of noxious and innocuous counterstimuli on experimentally induced itch and pain

31 March 2020

1 reference

Cutaneous field stimulation (CFS): a new powerful method to combat itch

31 March 2020

1 reference

Noxious heat and scratching decrease histamine-induced itch and skin blood flow

31 March 2020

1 reference

Attenuation of experimental pruritus and mechanically evoked dysesthesiae in an area of cutaneous allodynia

31 March 2020

1 reference

Influence of genotype, dose and sex on pruritogen-induced scratching behavior in the mouse

31 March 2020

1 reference

Variable sensitivity to noxious heat is mediated by differential expression of the CGRP gene

31 March 2020

1 reference

Enhancement of experimental pruritus and mechanically evoked dysesthesiae with local anesthesia

31 March 2020

1 reference

Opiate and H1 antagonist effects on histamine induced pruritus and alloknesis

31 March 2020

1 reference

The role of central mu opioid receptors in opioid-induced itch in primates.

31 March 2020

1 reference

The pruritus of cholestasis

31 March 2020

1 reference

Pain as a complication of use of opiate antagonists for symptom control in cholestasis

31 March 2020

1 reference

Opiate antagonist therapy for the pruritus of cholestasis: the avoidance of opioid withdrawal-like reactions

31 March 2020

1 reference

Norbinaltorphimine, a selective kappa-opioid receptor antagonist, induces an itch-associated response in mice

31 March 2020

1 reference

Activation of kappa-opioid receptors inhibits pruritus evoked by subcutaneous or intrathecal administration of morphine in monkeys.

31 March 2020

1 reference

Inhibitory effects of TRK-820 on systemic skin scratching induced by morphine in rhesus monkeys

31 March 2020

1 reference

Kappa-opioid system in uremic pruritus: multicenter, randomized, double-blind, placebo-controlled clinical studies

31 March 2020

1 reference

Butorphanol for treatment of intractable pruritus

31 March 2020

1 reference

Effects of classical algogens

31 March 2020

1 reference

Mechanisms of inflammatory pain

31 March 2020

1 reference

NGF rapidly increases membrane expression of TRPV1 heat-gated ion channels.

31 March 2020

1 reference

Novel class of pain drugs based on antagonism of NGF.

31 March 2020

1 reference

Increased intraepithelial innervation in women with vulvar vestibulitis syndrome

31 March 2020

1 reference

Cutaneous nerves in atopic dermatitis. A histological, immunohistochemical and electron microscopic study

31 March 2020

1 reference

Nerve growth factor and substance P are useful plasma markers of disease activity in atopic dermatitis

31 March 2020

1 reference

Gene expression and regulation of nerve growth factor in atopic dermatitis mast cells and the human mast cell line-1.

31 March 2020

1 reference

Increase in NGF content and nerve fiber sprouting in human allergic contact eczema

31 March 2020

1 reference

Increased nerve growth factor- and tyrosine kinase A-like immunoreactivities in prurigo nodularis skin -- an exploration of the cause of neurohyperplasia

31 March 2020

1 reference

A blocking antibody to nerve growth factor attenuates skeletal pain induced by prostate tumor cells growing in bone.

31 March 2020

1 reference

Effects of anti-nerve growth factor antibody on symptoms in the NC/Nga mouse, an atopic dermatitis model

31 March 2020

1 reference

Expression of nerve growth factor in itchy skins of atopic NC/NgaTnd mice.

31 March 2020

1 reference

Differential influence of nerve growth factor on neuropeptide expression in vivo: a novel role in peptide suppression in adult sensory neurons.

31 March 2020

1 reference

Role of central and peripheral tachykinin NK1 receptors in capsaicin-induced pain and hyperalgesia in mice.

31 March 2020

1 reference

NK1 (substance P) receptor antagonists--why are they not analgesic in humans?

31 March 2020

1 reference

Acute Effects of Substance P and Calcitonin Gene-Related Peptide in Human Skin – A Microdialysis Study

31 March 2020

1 reference

31 March 2020

1 reference

Calcitonin gene-related peptide receptor activation produces PKA- and PKC-dependent mechanical hyperalgesia and central sensitization

31 March 2020

1 reference

Neuropeptides concentrations in the skin of a murine (NC/Nga mice) model of atopic dermatitis

31 March 2020

1 reference

Neurogenic hyperalgesia: psychophysical studies of underlying mechanisms

31 March 2020

1 reference

Psychophysical Studies of the Itch Sensation and Itchy Skin (“Alloknesis”) Produced by Intracutaneous Injection of Histamine

31 March 2020

1 reference

Differential inhibitory effect on human nociceptive skin senses induced by local stimulation of thin cutaneous fibers

31 March 2020

1 reference

Effects of cutaneous histamine application in patients with sympathetic reflex dystrophy

31 March 2020

1 reference

Histamine-induced itch converts into pain in neuropathic hyperalgesia

31 March 2020

1 reference

Painful stimuli evoke itch in patients with chronic pruritus: central sensitization for itch

31 March 2020

1 reference

Pharmacologic advances in the systemic treatment of itch

31 March 2020

1 reference

The neurobiology of antiepileptic drugs for the treatment of nonepileptic conditions.

31 March 2020

1 reference

Brachioradial pruritus: response to treatment with gabapentin

31 March 2020

1 reference

Efficacy of gabapentin in the management of pruritus of unknown origin

31 March 2020

1 reference

The use of antidepressant drugs in dermatology

31 March 2020

1 reference

Paroxetine in the treatment of severe non-dermatological pruritus: a randomized, controlled trial

31 March 2020

1 reference

A Review of the Pharmacological and Clinical Profile of Mirtazapine

31 March 2020

1 reference

31 March 2020

Mirtazapine for pruritus

1 reference

Mirtazapine for reducing nocturnal itch in patients with chronic pruritus: a pilot study

31 March 2020

1 reference

Antinociceptive effects of the antidepressants amitriptyline, duloxetine, mirtazapine and citalopram in animal models of acute, persistent and neuropathic pain

31 March 2020

1 reference

Herpes zoster itch: preliminary epidemiologic data

31 March 2020

1 reference

Double-blind, crossover comparison of olopatadine and cetirizine versus placebo: suppressive effects on skin response to histamine iontophoresis

31 March 2020

1 reference

An evidence-based review of the efficacy of antihistamines in relieving pruritus in atopic dermatitis

31 March 2020

1 reference

Involvement of histamine H4 and H1 receptors in scratching induced by histamine receptor agonists in Balb C mice

31 March 2020

1 reference

Recent findings on how proinflammatory cytokines cause pain: peripheral mechanisms in inflammatory and neuropathic hyperalgesia.

31 March 2020

1 reference

Role of antigen-induced cytokine release in atopic pruritus

31 March 2020

1 reference

Expression of interleukin-6 and its receptor in the sciatic nerve and cultured Schwann cells: relation to 18-kD fibroblast growth factor-2

31 March 2020

1 reference

Interleukin 31, a cytokine produced by activated T cells, induces dermatitis in mice

31 March 2020

1 reference

Expression of IL-31 gene transcripts in NC/Nga mice with atopic dermatitis.

31 March 2020

1 reference

Involvement of IL-31 on scratching behavior in NC/Nga mice with atopic-like dermatitis

31 March 2020

1 reference

IL-31 is associated with cutaneous lymphocyte antigen-positive skin homing T cells in patients with atopic dermatitis

31 March 2020

1 reference

Proteinase-activated receptor-2 and hyperalgesia: A novel pain pathway

31 March 2020

1 reference

Proteinases and proteinase-activated receptor 2: a possible role to promote visceral hyperalgesia in rats

31 March 2020

1 reference

Proteinase-activated receptor-1 agonists attenuate nociception in response to noxious stimuli

31 March 2020

1 reference

Protease-activated receptors in inflammation, neuronal signaling and pain

31 March 2020

1 reference

Agonists of proteinase-activated receptor 2 induce inflammation by a neurogenic mechanism

31 March 2020

1 reference

Proteinase-activated receptor 2-mediated potentiation of transient receptor potential vanilloid subfamily 1 activity reveals a mechanism for proteinase-induced inflammatory pain.

31 March 2020

1 reference

Frontiers in pruritus research: scratching the brain for more effective itch therapy

31 March 2020

1 reference

Proteinase-activated receptor-2 mediates itch: a novel pathway for pruritus in human skin.

31 March 2020

1 reference

Protease-activated receptor-1 and platelet-derived growth factor in spinal cord neurons are implicated in neuropathic pain after nerve injury

31 March 2020

1 reference

Neutrophils and the kallikrein-kinin system in proteinase-activated receptor 4-mediated inflammation in rodents

31 March 2020

1 reference

Vanilloid receptor-1 (VR1) is widely expressed on various epithelial and mesenchymal cell types of human skin

31 March 2020

1 reference

Functional vanilloid receptors in cultured normal human epidermal keratinocytes

31 March 2020

1 reference

Expression of vanilloid receptor subtype 1 in cutaneous sensory nerve fibers, mast cells, and epithelial cells of appendage structures.

31 March 2020

1 reference

Direct activation of capsaicin receptors by products of lipoxygenases: endogenous capsaicin-like substances

31 March 2020

1 reference

Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns(4,5)P2-mediated inhibition

31 March 2020

1 reference

Bradykinin-12-lipoxygenase-VR1 signaling pathway for inflammatory hyperalgesia.

31 March 2020

1 reference

Desensitization of Capsaicin-activated Currents in the Vanilloid Receptor TRPV1 Is Decreased by the Cyclic AMP-dependent Protein Kinase Pathway

31 March 2020

1 reference

Biochemical pharmacology of the vanilloid receptor TRPV1. An update

31 March 2020

1 reference

The capsaicin receptor: a heat-activated ion channel in the pain pathway

31 March 2020

1 reference

The vanilloid receptor: a molecular gateway to the pain pathway

31 March 2020

1 reference

The role of calcium in the desensitization of capsaicin responses in rat dorsal root ganglion neurons

31 March 2020

1 reference

Activation of epidermal vanilloid receptor-1 induces release of proinflammatory mediators in human keratinocytes.

31 March 2020

1 reference

Efficacy of lidocaine patch 5% in the treatment of focal peripheral neuropathic pain syndromes: a randomized, double-blind, placebo-controlled study

31 March 2020

1 reference

Neurophysiological, neuroimmunological, and neuroendocrine basis of pruritus

31 March 2020

1 reference

A TRP channel that senses cold stimuli and menthol

31 March 2020

1 reference

ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures

31 March 2020

1 reference

ThermoTRP channels and beyond: mechanisms of temperature sensation

31 March 2020

1 reference

Distinct expression of TRPM8, TRPA1, and TRPV1 mRNAs in rat primary afferent neurons with adelta/c-fibers and colocalization with trk receptors

31 March 2020

1 reference

ThermoTRP channels and cold sensing: what are they really up to?

31 March 2020

1 reference

TRPV channels as thermosensory receptors in epithelial cells

31 March 2020

1 reference

Sensory characteristics of camphor

31 March 2020

1 reference

A heat-sensitive TRP channel expressed in keratinocytes

31 March 2020

1 reference

Camphor activates and strongly desensitizes the transient receptor potential vanilloid subtype 1 channel in a vanilloid-independent mechanism.

31 March 2020

1 reference

TRPV3 and TRPV4 mediate warmth-evoked currents in primary mouse keratinocytes

31 March 2020

1 reference

Impaired thermosensation in mice lacking TRPV3, a heat and camphor sensor in the skin.

31 March 2020

1 reference

Attacking pain at its source: new perspectives on opioids

31 March 2020

1 reference

Modern aspects of cutaneous neurogenic inflammation.

31 March 2020

1 reference

Neurophysiology of pruritus: cutaneous elicitation of itch

31 March 2020

1 reference

Double in situ hybridization study on coexistence of mu-, delta- and kappa-opioid receptor mRNAs with preprotachykinin A mRNA in the rat dorsal root ganglia

31 March 2020

1 reference

Molecular pharmacology of the opioid receptors.

31 March 2020

1 reference

Structure of a cannabinoid receptor and functional expression of the cloned cDNA

31 March 2020

1 reference

Molecular characterization of a peripheral receptor for cannabinoids

31 March 2020

1 reference

Evidence for the presence of CB1 cannabinoid receptors on peripheral neurones and for the existence of neuronal non-CB1 cannabinoid receptors

31 March 2020

1 reference

Localisation of cannabinoid CB(1) receptor immunoreactivity in the guinea pig and rat myenteric plexus

31 March 2020

1 reference

Cannabinoid 1 receptors are expressed by nerve growth factor- and glial cell-derived neurotrophic factor-responsive primary sensory neurones.

31 March 2020

1 reference

Distribution of cannabinoid receptor 1 (CB1) and 2 (CB2) on sensory nerve fibers and adnexal structures in human skin

31 March 2020

1 reference

Expression of central and peripheral cannabinoid receptors in human immune tissues and leukocyte subpopulations

31 March 2020

1 reference

Mast cells express a peripheral cannabinoid receptor with differential sensitivity to anandamide and palmitoylethanolamide

31 March 2020

1 reference

Induction of CB2 receptor expression in the rat spinal cord of neuropathic but not inflammatory chronic pain models

31 March 2020

1 reference

Deep tissue inflammation upregulates neuropeptides and evokes nociceptive behaviors which are modulated by a neuropeptide antagonist

31 March 2020

1 reference

The endocannabinoid system and its therapeutic exploitation

31 March 2020

1 reference

The endocannabinoid system in human keratinocytes. Evidence that anandamide inhibits epidermal differentiation through CB1 receptor-dependent inhibition of protein kinase C, activation protein-1, and transglutaminase.

31 March 2020

1 reference

Confocal microscopy and biochemical analysis reveal spatial and functional separation between anandamide uptake and hydrolysis in human keratinocytes.

31 March 2020

1 reference

Activation of peripheral cannabinoid receptors attenuates cutaneous hyperalgesia produced by a heat injury

31 March 2020

1 reference

Signal transduction activated by cannabinoid receptors.

31 March 2020

1 reference

Cannabinoid agonists attenuate capsaicin-induced responses in human skin

31 March 2020

1 reference

Histamine induced responses are attenuated by a cannabinoid receptor agonist in human skin

31 March 2020

1 reference

Evidence for novel cannabinoid receptors

31 March 2020

1 reference

Cannabinoids and reward: interactions with the opioid system.

31 March 2020

1 reference

Molecular and cellular basis of cannabinoid and opioid interactions.

31 March 2020

1 reference

Molecular mechanisms involved in the asymmetric interaction between cannabinoid and opioid systems

31 March 2020

1 reference

CB2 cannabinoid receptor activation produces antinociception by stimulating peripheral release of endogenous opioids

31 March 2020

1 reference

The ability of humans to localise noxious stimuli

31 March 2020

1 reference

Novel classes of responsive and unresponsive C nociceptors in human skin

31 March 2020

1 reference

Functional attributes discriminating mechano-insensitive and mechano-responsive C nociceptors in human skin

31 March 2020

1 reference

Central origin of secondary mechanical hyperalgesia

31 March 2020

1 reference

Active "itch fibers" in chronic pruritus

31 March 2020

1 reference

Chemical response pattern of different classes of C-nociceptors to pruritogens and algogens

31 March 2020

1 reference

Electrically evoked itch in humans

31 March 2020

1 reference

Mucunain, the active pruritogenic proteinase of cowhage

31 March 2020

1 reference

Response to an itch-producing substance in cat. II. Cutaneous receptor populations with unmyelinated axons

31 March 2020

1 reference

Response of cat ventrolateral spinal axons to an itch-producing stimulus (cowhage)

31 March 2020

1 reference

New aspects of itch pathophysiology: component analysis of atopic itch using the 'Eppendorf Itch Questionnaire'

31 March 2020

1 reference

Itch characteristics in Chinese patients with atopic dermatitis using a new questionnaire for the assessment of pruritus

31 March 2020

1 reference

The McGill Pain Questionnaire: Major properties and scoring methods

31 March 2020

1 reference

The sensory response to capsaicin during repeated topical exposures: differential effects on sensations of itching and pungency

31 March 2020

1 reference

Comparison of responses of primate spinothalamic tract neurons to pruritic and algogenic stimuli

31 March 2020

1 reference

A neural pathway for itch.

31 March 2020

1 reference

The cortical representation of pain

31 March 2020

1 reference

Pain and emotion interactions in subregions of the cingulate gyrus

31 March 2020

1 reference

Human brain mechanisms of pain perception and regulation in health and disease.

31 March 2020

1 reference

Somatotopic organisation of the human insula to painful heat studied with high resolution functional imaging.

31 March 2020

1 reference

A new view of pain as a homeostatic emotion

31 March 2020

1 reference

An fMRI study of the anterior cingulate cortex and surrounding medial wall activations evoked by noxious cutaneous heat and cold stimuli

31 March 2020

1 reference

Regional intensive and temporal patterns of functional MRI activation distinguishing noxious and innocuous contact heat.

31 March 2020

1 reference

From nociception to pain perception: imaging the spinal and supraspinal pathways.

31 March 2020

1 reference

Urge to scratch represented in the human cerebral cortex during itch

31 March 2020

1 reference

Central activation by histamine-induced itch: analogies to pain processing: a correlational analysis of O-15 H2O positron emission tomography studies

31 March 2020

1 reference

Processing of histamine-induced itch in the human cerebral cortex: a correlation analysis with dermal reactions.

31 March 2020

1 reference

Imaging of central itch modulation in the human brain using positron emission tomography

31 March 2020

1 reference

Brain activation by histamine prick test-induced itch.

31 March 2020

1 reference

THE FINE ART OF SCRATCHING.

31 March 2020

1 reference

Studies on itching. I. Contributions toward an understanding of the physiology of masochism

31 March 2020

1 reference

The human orbitofrontal cortex: linking reward to hedonic experience

31 March 2020

1 reference

Regional mu opioid receptor regulation of sensory and affective dimensions of pain

31 March 2020

1 reference

Referred itch (Mitempfindungen)

31 March 2020

1 reference

Observing conspecifics scratching induces a contagion of scratching in Japanese monkeys (Macaca fuscata)

31 March 2020

1 reference

31 March 2020

THE MIRROR-NEURON SYSTEM

1 reference

Neural mechanisms of imitation

31 March 2020

1 reference

Yearning to yawn: the neural basis of contagious yawning

31 March 2020

1 reference

Intradermal recombinant human nerve growth factor induces pressure allodynia and lowered heat-pain threshold in humans

31 March 2020

1 reference

31 March 2020

Cannabis and the brain

1 reference

ET--phone the pain clinic

31 March 2020

1 reference

Scratching behavior in mice induced by the proteinase-activated receptor-2 agonist, SLIGRL-NH2.

31 March 2020

1 reference

Influence of calcitonin gene-related peptide on histamine- and substance P-induced itch, flare and weal in humans

31 March 2020

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Encoding of burning pain from capsaicin-treated human skin in two categories of unmyelinated nerve fibres

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NRN1950

2 references

Consolidated OpenCitations Corpus – April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16791143%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

25 December 2019

1013182832

0 references

1 reference

Consolidated OpenCitations Corpus – April 2017

2 references

Consolidated OpenCitations Corpus – April 2017