Coordinated regulation of protein synthesis and degradation by mTORC1 (Q28244300)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043031%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

title

Coordinated regulation of protein synthesis and degradation by mTORC1 (English)

1 reference

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10 March 2020

2

1 reference

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10 March 2020

Scott B Widenmaier

5

1 reference

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10 March 2020

6

Gökhan S Hotamisligil

1 reference

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10 March 2020

author name string

Yinan Zhang

1

1 reference

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10 March 2020

John R Dreier

3

1 reference

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10 March 2020

Stéphane J H Ricoult

4

1 reference

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10 March 2020

David J Kwiatkowski

7

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10 March 2020

Brendan D Manning

8

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10 March 2020

language of work or name

English

0 references

publication date

13 July 2014

1 reference

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10 March 2020

1 reference

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10 March 2020

volume

513

1 reference

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10 March 2020

issue

7518

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10 March 2020

page(s)

440-443

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describes a project that uses

10 March 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4402229/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

p97-dependent retrotranslocation and proteolytic processing govern formation of active Nrf1 upon proteasome inhibition

1 reference

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Nuclear factor-erythroid 2-related factor 1 regulates expression of proteasome genes in hepatocytes and protects against endoplasmic reticulum stress and steatosis in mice

20 March 2017

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Akt stimulates hepatic SREBP1c and lipogenesis through parallel mTORC1-dependent and independent pathways

20 March 2017

1 reference

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Proteasomal Degradation Is Transcriptionally Controlled by TCF11 via an ERAD-Dependent Feedback Loop

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4402229

Transcription factor Nrf1 mediates the proteasome recovery pathway after proteasome inhibition in mammalian cells

20 March 2017

1 reference

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Biopython: freely available Python tools for computational molecular biology and bioinformatics

20 March 2017

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Clustal W and Clustal X version 2.0

20 March 2017

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WebLogo: A Sequence Logo Generator

20 March 2017

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A mouse model of TSC1 reveals sex-dependent lethality from liver hemangiomas, and up-regulation of p70S6 kinase activity in Tsc1 null cells

20 March 2017

1 reference

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A simplified system for generating recombinant adenoviruses

20 March 2017

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The mammalian unfolded protein response

20 March 2017

1 reference

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Activation of a metabolic gene regulatory network downstream of mTOR complex 1

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4402229

Signal integration by mTORC1 coordinates nutrient input with biosynthetic output.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4402229

mTOR in aging, metabolism, and cancer

29 September 2017

1 reference

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Failure of amino acid homeostasis causes cell death following proteasome inhibition.

29 September 2017

1 reference

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Graded loss of tuberin in an allelic series of brain models of TSC correlates with survival, and biochemical, histological and behavioral features

29 September 2017

1 reference

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Autophagy in the cellular energetic balance

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4402229

Genome-wide occupancy of SREBP1 and its partners NFY and SP1 reveals novel functional roles and combinatorial regulation of distinct classes of genes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4402229

Microarray analyses of SREBP-1a and SREBP-1c target genes identify new regulatory pathways in muscle

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4402229

The TSC1-TSC2 complex is required for proper activation of mTOR complex 2

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4402229

Loss of the tuberous sclerosis complex tumor suppressors triggers the unfolded protein response to regulate insulin signaling and apoptosis

29 September 2017

1 reference

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Selective coactivator interactions in gene activation by SREBP-1a and -1c.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4402229

Loss of Tsc1/Tsc2 activates mTOR and disrupts PI3K-Akt signaling through downregulation of PDGFR

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4402229

Autophagy is important in islet homeostasis and compensatory increase of beta cell mass in response to high-fat diet

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4402229

Sterols regulate 3β-hydroxysterol Δ24-reductase (DHCR24) via dual sterol regulatory elements: cooperative induction of key enzymes in lipid synthesis by Sterol Regulatory Element Binding Proteins.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4402229

A balance of protein synthesis and proteasome-dependent degradation determines the maintenance of LTP.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4402229

Mutation in TSC2 and activation of mammalian target of rapamycin signalling pathway in renal angiomyolipoma

27 November 2018

1 reference

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27 November 2018

Identifiers

DOI

10.1038/NATURE13492

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043031%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

10 March 2020

1026772416

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043031%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

PubMed publication ID

25043031

2 references