Characterisation of the new EpCAM-specific antibody HO-3: implications for trifunctional antibody immunotherapy of cancer (Q28235980)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17622246%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

title

Characterisation of the new EpCAM-specific antibody HO-3: implications for trifunctional antibody immunotherapy of cancer (English)

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1 January 2020

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2

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1 January 2020

author name string

P Ruf

1

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1 January 2020

M Jäger

3

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1 January 2020

K Fellinger

4

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1 January 2020

J Atz

5

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1 January 2020

H Lindhofer

6

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1 January 2020

language of work or name

English

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publication date

10 July 2007

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British Journal of Cancer

1 January 2020

published in

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1 January 2020

volume

97

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1 January 2020

issue

3

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1 January 2020

page(s)

315-321

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MUC1 is a promising therapeutic target for prostate cancer therapy

1 January 2020

cites work

1 reference

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EpCAM (CD326) finding its role in cancer

20 March 2017

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EpCAM is overexpressed in breast cancer and is a potential target for breast cancer gene therapy

20 March 2017

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The carcinoma-associated antigen EpCAM upregulates c-myc and induces cell proliferation

20 March 2017

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EpCAM: A New Therapeutic Target for an Old Cancer Antigen

20 March 2017

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Edrecolomab alone or in combination with fluorouracil and folinic acid in the adjuvant treatment of stage III colon cancer: a randomised study

20 March 2017

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The biology of the 17-1A antigen (Ep-CAM)

20 March 2017

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Ep-CAM: a human epithelial antigen is a homophilic cell-cell adhesion molecule

20 March 2017

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Preferential species-restricted heavy/light chain pairing in rat/mouse quadromas. Implications for a single-step purification of bispecific antibodies

20 March 2017

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Monoclonal antibodies in cell-mediated cytotoxicity against human melanoma and colorectal carcinoma

20 March 2017

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Phase I trial of the trifunctional anti-HER2 x anti-CD3 antibody ertumaxomab in metastatic breast cancer

20 March 2017

1 reference

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Frequent high-level expression of the immunotherapeutic target Ep-CAM in colon, stomach, prostate and lung cancers.

29 September 2017

1 reference

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High concentrations of therapeutic IgG1 antibodies are needed to compensate for inhibition of antibody-dependent cellular cytotoxicity by excess endogenous immunoglobulin G.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360319

Combined treatment of metastatic breast cancer (MBC) by high-dose chemotherapy (HDCT) and bispecific antibodies: a pilot study.

29 September 2017

1 reference

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What makes MUC1 a tumor antigen?

29 September 2017

1 reference

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Immunotherapy of malignant ascites with trifunctional antibodies

29 September 2017

1 reference

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Opsonization with a trifunctional bispecific (alphaCD3 x alphaEpCAM) antibody results in efficient lysis in vitro and in vivo of EpCAM positive tumor cells by cytotoxic T lymphocytes

29 September 2017

1 reference

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A revival of bispecific antibodies

29 September 2017

1 reference

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Tumor-specific glycosylation of the carcinoma-associated epithelial cell adhesion molecule EpCAM in head and neck carcinomas

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360319

Determination of disulfide bond assignments and N-glycosylation sites of the human gastrointestinal carcinoma antigen GA733-2 (CO17-1A, EGP, KS1-4, KSA, and Ep-CAM).

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2360319

The Fc-region of a new class of intact bispecific antibody mediates activation of accessory cells and NK cells and induces direct phagocytosis of tumour cells

29 September 2017

1 reference

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Immune evasion of tumor cells using membrane-bound complement regulatory proteins

29 September 2017

1 reference

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Antigen sequence- and library-based mapping of linear and discontinuous protein-protein-interaction sites by spot synthesis.

29 September 2017

1 reference

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Randomised trial of monoclonal antibody for adjuvant therapy of resected Dukes' C colorectal carcinoma. German Cancer Aid 17-1A Study Group

29 September 2017

1 reference

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Isolation, partial characterization, and molecular cloning of a human colon adenocarcinoma cell-surface glycoprotein recognized by the C215 mouse monoclonal antibody

29 September 2017

1 reference

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Effect of glycosylation on MUC1 humoral immune recognition: NMR studies of MUC1 glycopeptide-antibody interactions

2 June 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJC.6603881

A tumor-associated glycoprotein that blocks MHC class II-dependent antigen presentation by dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJC.6603881

Lysis of prostate carcinoma cells by trifunctional bispecific antibodies (alpha EpCAM x alpha CD3).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJC.6603881

Prognostic significance of Ep-CAM AND Her-2/neu overexpression in invasive breast cancer

21 January 2018

1 reference

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Overexpression of epithelial cell adhesion molecule (Ep-CAM) is an independent prognostic marker for reduced survival of patients with epithelial ovarian cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJC.6603881

Overexpression of epithelial cell adhesion molecule antigen in gallbladder carcinoma is an independent marker for poor survival

21 January 2018

1 reference

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Neutralization of immunosuppression by antibodies against variable as well as constant regions of monoclonal anti-Thy-1 xenoantibodies and their ability to be suppressed by initial T cell depletion

21 January 2018

1 reference

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The epithelial cell surface antigen 17-1A, a target for antibody-mediated tumor therapy: its biochemical nature, tissue distribution and recognition by different monoclonal antibodies

27 November 2018

1 reference

12 December 2020

Tumor-associated antigen expression of primary and metastatic colon carcinomas detected by monoclonal antibody 17-1A

1 reference

12 December 2020

Ep-CAM overexpression in breast cancer as a predictor of survival

1 reference

12 December 2020

The epithelial glycoprotein 2 (EGP-2) promoter-driven epithelial-specific expression of EGP-2 in transgenic mice: a new model to study carcinoma-directed immunotherapy

1 reference

12 December 2020

Induction of a long-lasting antitumor immunity by a trifunctional bispecific antibody

1 reference

12 December 2020

Immunotherapy with low and high affinity monoclonal antibodies 17-1A and 323/A3 in a nude mouse xenograft carcinoma model

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12 December 2020

Bispecific antibodies target operationally tumor-specific antigens in two leukemia relapse models

1 reference

12 December 2020

Simultaneous activation of T cells and accessory cells by a new class of intact bispecific antibody results in efficient tumor cell killing

1 reference

12 December 2020

ING-1, a monoclonal antibody targeting Ep-CAM in patients with advanced adenocarcinomas

1 reference

12 December 2020

In vitro and in vivo activity of MT201, a fully human monoclonal antibody for pancarcinoma treatment

1 reference

12 December 2020

Identifiers

DOI

10.1038/SJ.BJC.6603881

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17622246%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

1 January 2020

0 references

1 reference

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1 January 2020

PubMed publication ID

17622246

1 reference