'Hard' and 'soft' principles defining the structure, function and regulation of keratin intermediate filaments (Q28215621)

Current Opinion in Cell Biology

Europe PubMed Central

title

'Hard' and 'soft' principles defining the structure, function and regulation of keratin intermediate filaments (English)

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author name string

Pierre A Coulombe

series ordinal

1

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M Bishr Omary

series ordinal

2

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language of work or name

English

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publication date

February 2002

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published in

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volume

14

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issue

1

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page(s)

110-22

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cites work

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An autonomous folding unit mediates the assembly of two-stranded coiled coils

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A distinct 14 residue site triggers coiled-coil formation in cortexillin I

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Coiled-coil trigger motifs in the 1B and 2B rod domain segments are required for the stability of keratin intermediate filaments

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In vitro assembly and structure of trichocyte keratin intermediate filaments: a novel role for stabilization by disulfide bonding

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Divide-and-conquer crystallographic approach towards an atomic structure of intermediate filaments

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The intermediate filament protein consensus motif of helix 2B: its atomic structure and contribution to assembly

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Viscoelastic properties of vimentin compared with other filamentous biopolymer networks

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A 'hot-spot' mutation alters the mechanical properties of keratin filament networks

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Pairwise assembly determines the intrinsic potential for self-organization and mechanical properties of keratin filaments

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7 January 2021

The nonhelical tail domain of keratin 14 promotes filament bundling and enhances the mechanical properties of keratin intermediate filaments in vitro

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Evidence for novel functions of the keratin tail emerging from a mutation causing ichthyosis hystrix

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Complete cytolysis and neonatal lethality in keratin 5 knockout mice reveal its fundamental role in skin integrity and in epidermolysis bullosa simplex

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The two functional keratin 6 genes of mouse are differentially regulated and evolved independently from their human orthologs.

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A reporter transgene based on a human keratin 6 gene promoter is specifically expressed in the periderm of mouse embryos.

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Inflammatory versus proliferative processes in epidermis. Tumor necrosis factor alpha induces K6b keratin synthesis through a transcriptional complex containing NFkappa B and C/EBPbeta

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Introducing a null mutation in the mouse K6alpha and K6beta genes reveals their essential structural role in the oral mucosa

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A novel human type II cytokeratin, K6hf, specifically expressed in the companion layer of the hair follicle

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Keratin 17 expression in the hard epithelial context of the hair and nail, and its relevance for the pachyonychia congenita phenotype

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Formation of a normal epidermis supported by increased stability of keratins 5 and 14 in keratin 10 null mice.

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7 January 2021

Cytokeratins 8 and 19 in the mouse placental development

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7 January 2021

Targeted deletion of keratins 18 and 19 leads to trophoblast fragility and early embryonic lethality

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7 January 2021

Lessons from Keratin 18 Knockout Mice: Formation of Novel Keratin Filaments, Secondary Loss of Keratin 7 and Accumulation of Liver-specific Keratin 8-Positive Aggregates

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Functional differences between keratins of stratified and simple epithelia

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The functional diversity of epidermal keratins revealed by the partial rescue of the keratin 14 null phenotype by keratin 16.

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7 January 2021

In vitro characteristics of early epidermal progenitors isolated from keratin 14 (K14)-deficient mice: insights into the role of keratin 17 in mouse keratinocytes

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7 January 2021

A keratin 14 'knockout' mutation in recessive epidermolysis bullosa simplex resulting in less severe disease

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Specialized keratin expression pattern in human ridged skin as an adaptation to high physical stress

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Modulation of cell proliferation by cytokeratins K10 and K16

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Forced expression of keratin 16 alters the adhesion, differentiation, and migration of mouse skin keratinocytes

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Increased levels of keratin 16 alter epithelialization potential of mouse skin keratinocytes in vivo and ex vivo

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7 January 2021

Keratin 15 expression in stratified epithelia: downregulation in activated keratinocytes

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K15 expression implies lateral differentiation within stratified epithelial basal cells

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7 January 2021

Focal activation of a mutant allele defines the role of stem cells in mosaic skin disorders

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7 January 2021

Cytokeratin 8 protects from hepatotoxicity, and its ratio to cytokeratin 18 determines the ability of hepatocytes to form Mallory bodies

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7 January 2021

Effects of keratin filament disruption on exocrine pancreas-stimulated secretion and susceptibility to injury

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7 January 2021

Simple epithelial keratins are dispensable for cytoprotection in two pancreatitis models

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7 January 2021

Mallory bodies revisited

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7 January 2021

Early perturbations in keratin and actin gene expression and fibrillar organisation in griseofulvin-fed mouse liver

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7 January 2021

A novel keratin 5 mutation (K5V186L) in a family with EBS-K: a conservative substitution can lead to development of different disease phenotypes

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7 January 2021

Effect of mutation and phosphorylation of type I keratins on their caspase-mediated degradation.

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7 January 2021

Keratin 8 mutations in patients with cryptogenic liver disease

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7 January 2021

Keratin 17 mutations cause either steatocystoma multiplex or pachyonychia congenita type 2.

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7 January 2021

Effects of keratin 14 ablation on the clinical and cellular phenotype in a kindred with recessive epidermolysis bullosa simplex

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7 January 2021

Are desmosomes more than tethers for intermediate filaments?

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7 January 2021

Bridging cytoskeletal intersections.

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7 January 2021

The function of plakophilin 1 in desmosome assembly and actin filament organization

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7 January 2021

Dissection of protein linkage between keratins and pinin, a protein with dual location at desmosome-intermediate filament complex and in the nucleus

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7 January 2021

Phosphorylation of human keratin 18 serine 33 regulates binding to 14-3-3 proteins

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7 January 2021

Keratin-dependent, epithelial resistance to tumor necrosis factor-induced apoptosis

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7 January 2021

Identification of 12-lipoxygenase interaction with cellular proteins by yeast two-hybrid screening

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7 January 2021

The RNA polymerase II core subunit 11 interacts with keratin 19, a component of the intermediate filament proteins

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https://api.crossref.org/works/10.1016%2FS0955-0674%2801%2900301-5

7 January 2021

Identification of Mrj, a DnaJ/Hsp40 family protein, as a keratin 8/18 filament regulatory protein

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7 January 2021

A cytoplasmic protein, bystin, interacts with trophinin, tastin, and cytokeratin and may be involved in trophinin-mediated cell adhesion between trophoblast and endometrial epithelial cells

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7 January 2021

Characterization of the major physiologic phosphorylation site of human keratin 19 and its role in filament organization.

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7 January 2021

Insights into the dynamic properties of keratin intermediate filaments in living epithelial cells

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7 January 2021

Mutation of a major keratin phosphorylation site predisposes to hepatotoxic injury in transgenic mice

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7 January 2021

Glycosylation of nucleocytoplasmic proteins: signal transduction and O-GlcNAc

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7 January 2021

A highly conserved lysine residue on the head domain of type II keratins is essential for the attachment of keratin intermediate filaments to the cornified cell envelope through isopeptide crosslinking by transglutaminases

1 reference

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7 January 2021

Keratins turn over by ubiquitination in a phosphorylation-modulated fashion

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7 January 2021

Impairment of the ubiquitin-proteasome system by protein aggregation

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7 January 2021

Caspase Cleavage of Keratin 18 and Reorganization of Intermediate Filaments during Epithelial Cell Apoptosis

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7 January 2021

Apoptosis Generates Stable Fragments of Human Type I Keratins

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7 January 2021

Apoptosis-induced cleavage of keratin 15 and keratin 17 in a human breast epithelial cell line

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7 January 2021

Immunocytochemical detection and mapping of a cytokeratin 18 neo-epitope exposed during early apoptosis

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7 January 2021

Active caspases and cleaved cytokeratins are sequestered into cytoplasmic inclusions in TRAIL-induced apoptosis

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7 January 2021

Mouse keratin 4 is necessary for internal epithelial integrity

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Delayed wound healing in keratin 6a knockout mice

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7 January 2021

Colorectal hyperplasia and inflammation in keratin 8-deficient FVB/N mice

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7 January 2021

Simple epithelium keratins 8 and 18 provide resistance to Fas-mediated apoptosis. The protection occurs through a receptor-targeting modulation

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https://api.crossref.org/works/10.1016%2FS0955-0674%2801%2900301-5

7 January 2021

Keratin attenuates tumor necrosis factor-induced cytotoxicity through association with TRADD

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7 January 2021

Inhibition of protein kinase B (PKB) and PKCzeta mediates keratin K10-induced cell cycle arrest

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7 January 2021

10.1016/S0955-0674(01)00301-5

Identifiers

DOI

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

PubMed publication ID

11792552

1 reference

Consolidated OpenCitations Corpus – April 2017