The multispanning membrane protein Ste24p catalyzes CAAX proteolysis and NH2-terminal processing of the yeast a-factor precursor (Q27935263)

1 December 2016

title

The multispanning membrane protein Ste24p catalyzes CAAX proteolysis and NH2-terminal processing of the yeast a-factor precursor (English)

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Zinc metalloprotease YJR117W

1 December 2016

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CAAX prenyl protease YMR274C

GOA release 2020-03-11

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Journal of Biological Chemistry

GOA release 2020-03-11

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A Tam

1

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W K Schmidt

series ordinal

2

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S Michaelis

series ordinal

3

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language of work or name

English

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publication date

14 December 2001

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published in

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Protein prenylation: molecular mechanisms and functional consequences

1 December 2016

volume

276

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issue

50

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page(s)

46798-806

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cites work

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https://api.crossref.org/works/10.1074%2FJBC.M106150200

Prenyl proteins in eukaryotic cells: a new type of membrane anchor

21 January 2018

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Significance of C-terminal cysteine modifications to the biological activity of the Saccharomyces cerevisiae a-factor mating pheromone

21 January 2018

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The effect of posttranslational modifications on the interaction of Ras2 with adenylyl cyclase

21 January 2018

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Modulation of Ras and a-factor function by carboxyl-terminal proteolysis

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M106150200

A novel membrane-associated metalloprotease, Ste24p, is required for the first step of NH2-terminal processing of the yeast a-factor precursor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106150200

Dual roles for Ste24p in yeast a-factor maturation: NH2-terminal proteolysis and COOH-terminal CAAX processing

21 January 2018

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Endoplasmic reticulum membrane localization of Rce1p and Ste24p, yeast proteases involved in carboxyl-terminal CAAX protein processing and amino-terminal a-factor cleavage

21 January 2018

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Studies with recombinant Saccharomyces cerevisiae CaaX prenyl protease Rce1p

21 January 2018

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The CaaX proteases, Afc1p and Rce1p, have overlapping but distinct substrate specificities

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M106150200

Cloning and characterization of a mammalian prenyl protein-specific protease

21 January 2018

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Biogenesis of the Saccharomyces cerevisiae mating pheromone a-factor

21 January 2018

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Role of yeast insulin-degrading enzyme homologs in propheromone processing and bud site selection

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The a-factor pheromone of Saccharomyces cerevisiae is essential for mating

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Hsp70 molecular chaperone facilitates endoplasmic reticulum-associated protein degradation of cystic fibrosis transmembrane conductance regulator in yeast

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Functional assays for analysis of yeast ste6 mutants.

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The Saccharomyces cerevisiae prenylcysteine carboxyl methyltransferase Ste14p is in the endoplasmic reticulum membrane

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Topological and mutational analysis of Saccharomyces cerevisiae Ste14p, founding member of the isoprenylcysteine carboxyl methyltransferase family

21 January 2018

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20 Ras and a-factor converting enzyme

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Biochemical studies of Zmpste24-deficient mice

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14 Removal and replacement of metal ions in metallopeptidases

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Coatomer is essential for retrieval of dilysine-tagged proteins to the endoplasmic reticulum

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A model recognition approach to the prediction of all-helical membrane protein structure and topology

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Prediction of transmembrane alpha-helices in prokaryotic membrane proteins: the dense alignment surface method

21 January 2018

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Prediction of Membrane Protein Topology Utilizing Multiple Sequence Alignments

21 January 2018

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Preference functions for prediction of membrane-buried helices in integral membrane proteins

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Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans

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Membrane topology of S2P, a protein required for intramembranous cleavage of sterol regulatory element-binding proteins

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The Role of presenilins in gamma-secretase activity

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Purification, characterization, and primary structure of Escherichia coli protease VII with specificity for paired basic residues: identity of protease VII and OmpT

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FtsH (HflB) is an ATP-dependent protease selectively acting on SecY and some other membrane proteins

21 January 2018

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Substrate specificity of the integral membrane protease OmpT determined by spatially addressed peptide libraries

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The carboxyl methyltransferase modifying G proteins is a metalloenzyme

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RAM2, an essential gene of yeast, and RAM1 encode the two polypeptide components of the farnesyltransferase that prenylates a-factor and Ras proteins

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Identification and chromosomal location of two human genes encoding enzymes potentially involved in proteolytic maturation of farnesylated proteins

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Identification of a human cDNA encoding a novel protein structurally related to the yeast membrane-associated metalloprotease, Ste24p

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Ras protein farnesyltransferase: A strategic target for anticancer therapeutic development

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Farnesyltransferase inhibitors: antineoplastic properties, mechanisms of action, and clinical prospects

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A simple method for displaying the hydropathic character of a protein

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Reconstitution of the Ste24p-dependent N-terminal proteolytic step in yeast a-factor biogenesis

21 January 2018

1 reference

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21 Yeast STE 14 methyltransferase, expressed as TrpE-STE 14 fusion protein in Escherichia coli, for in Vitro Carboxylmethylation of prenylated polypeptides

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Identifiers

DOI

10.1074/JBC.M106150200

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