Parkinson's disease and immune system: is the culprit LRRKing in the periphery? (Q27687171)

Marco Bisaglia

series ordinal

3

1 reference

Journal of Neuroinflammation

language of work or name

1 reference

9 July 2012

6 references

25 April 2019

12 September 2019

28 September 2019

8 April 2021

8 October 2022

6 references

25 April 2019

12 September 2019

28 September 2019

8 April 2021

8 October 2022

9

1 reference

page(s)

94

1 reference

Creative Commons Attribution 2.0 Generic

copyright license

5 references

25 April 2019

12 September 2019

28 September 2019

8 April 2021

on focus list of Wikimedia project

8 October 2022

copyright status

copyrighted

0 references

ScienceSource

0 references

cites work

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14-3-3 binding to LRRK2 is disrupted by multiple Parkinson's disease-associated mutations and regulates cytoplasmic localization

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The familial Parkinsonism gene LRRK2 regulates neurite process morphology

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Loss of leucine-rich repeat kinase 2 causes age-dependent bi-phasic alterations of the autophagy pathway

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29 September 2017

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LRRK2 is involved in the IFN-gamma response and host response to pathogens

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Central and systemic IL-1 exacerbates neurodegeneration and motor symptoms in a model of Parkinson's disease

29 September 2017

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The chaperone activity of heat shock protein 90 is critical for maintaining the stability of leucine-rich repeat kinase 2.

29 September 2017

1 reference

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Anti-TNF therapy for Crohn's disease

29 September 2017

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Distribution of major histocompatibility complex class II-positive microglia and cytokine profile of Parkinson's disease brains

29 September 2017

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Developmental regulation of leucine-rich repeat kinase 1 and 2 expression in the brain and other rodent and human organs: Implications for Parkinson's disease.

21 January 2018

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Anatomical localization of leucine-rich repeat kinase 2 in mouse brain

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Distribution of PINK1 and LRRK2 in rat and mouse brain

21 January 2018

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Transcriptional profile of Parkinson blood mononuclear cells with LRRK2 mutation

21 January 2018

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Phosphopeptide analysis reveals two discrete clusters of phosphorylation in the N-terminus and the Roc domain of the Parkinson-disease associated protein kinase LRRK2.

21 January 2018

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LRRK2 is expressed in B-2 but not in B-1 B cells, and downregulated by cellular activation.

21 January 2018

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Parkinson's disease-linked leucine-rich repeat kinase 2(R1441G) mutation increases proinflammatory cytokine release from activated primary microglial cells and resultant neurotoxicity.

21 January 2018

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Amplification and overexpression of the c-erbB-2 protooncogene in human gastric cancer

21 January 2018

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Tumor necrosis factor-alpha (TNF-alpha) increases both in the brain and in the cerebrospinal fluid from parkinsonian patients

21 January 2018

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TNFalpha transport across the blood-brain barrier is abolished in receptor knockout mice

21 January 2018

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Involvement of interferon-gamma in microglial-mediated loss of dopaminergic neurons.

21 January 2018

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Immunocytochemical analysis of tumor necrosis factor and its receptors in Parkinson's disease

21 January 2018

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Blood-brain barrier dysfunction in parkinsonian midbrain in vivo

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6-Hydroxydopamine-induced alterations in blood-brain barrier permeability

21 January 2018

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The history of otolaryngology in Canada: Laval University.

21 January 2018

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The role of interferon gamma in the pathogenesis of Crohn's disease

27 November 2018

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Interleukin (IL)-1 beta, IL-2, IL-4, IL-6 and transforming growth factor-alpha levels are elevated in ventricular cerebrospinal fluid in juvenile parkinsonism and Parkinson's disease.

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Identifiers

DOI

10.1186/1742-2094-9-94

1 reference

Dimensions Publication ID

1 reference

9 September 2019

https://scigraph.springernature.com/pub.10.1186/1742-2094-9-94

1 reference

1 reference

PubMed publication ID

22594666

1 reference