Targeted inhibition of mutant IDH2 in leukemia cells induces cellular differentiation (Q27684364)

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28 February 2020

title

Targeted inhibition of mutant IDH2 in leukemia cells induces cellular differentiation (English)

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28 February 2020

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Virginie Penard-Lacronique

4

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28 February 2020

Cyril Quivoron

16

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28 February 2020

Stéphane de Botton

30

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28 February 2020

author name string

Fang Wang

1

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28 February 2020

Jeremy Travins

2

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28 February 2020

Byron DeLaBarre

3

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Stefanie Schalm

5

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28 February 2020

Erica Hansen

6

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28 February 2020

Kimberly Straley

7

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28 February 2020

Andrew Kernytsky

8

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28 February 2020

Wei Liu

9

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28 February 2020

Camelia Gliser

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28 February 2020

Hua Yang

11

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28 February 2020

Stefan Gross

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Erin Artin

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Veronique Saada

14

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Elena Mylonas

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28 February 2020

Janeta Popovici-Muller

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Jeffrey O Saunders

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28 February 2020

Francesco G Salituro

19

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Shunqi Yan

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28 February 2020

Stuart Murray

21

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Wentao Wei

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28 February 2020

Yi Gao

23

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28 February 2020

Lenny Dang

24

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28 February 2020

Marion Dorsch

25

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28 February 2020

Sam Agresta

26

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28 February 2020

David P Schenkein

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28 February 2020

Scott A Biller

28

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28 February 2020

Shinsan M Su

29

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Katharine E Yen

31

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language of work or name

English

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publication date

4 April 2013

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28 February 2020

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28 February 2020

volume

340

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28 February 2020

issue

6132

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28 February 2020

page(s)

622-626

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Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

28 February 2020

cites work

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1234769

The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases

20 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1234769

Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases

20 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1234769

IDH mutation impairs histone demethylation and results in a block to cell differentiation

20 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1234769

The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate

20 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1234769

Structural studies ofSaccharomyces cerevesiaemitochondrial NADP-dependent isocitrate dehydrogenase in different enzymatic states reveal substantial conformational changes during the catalytic reaction

20 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1234769

Molecular mechanisms of "off-on switch" of activities of human IDH1 by tumor-associated mutation R132H

20 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1234769

Identification of a hierarchy of multipotent hematopoietic progenitors in human cord blood

20 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1234769

Overview of the CCP4 suite and current developments

20 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1234769

Features and development of Coot

20 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1234769

Structure validation by Calpha geometry: phi,psi and Cbeta deviation

20 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1234769

IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype

20 April 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1234769

Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation

20 April 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1234769

20 April 2017

Identifiers

DOI

10.1126/SCIENCE.1234769

2 references

Consolidated OpenCitations Corpus – April 2017

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28 February 2020

ADS bibcode

2013Sci...340..622W

0 references

1 reference

Consolidated OpenCitations Corpus – April 2017

2 references

Consolidated OpenCitations Corpus – April 2017