Hidden alternative structures of proline isomerase essential for catalysis (Q27658415)

2

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Sheena C Degnan

3

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Renske Erion

4

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Dorothee Kern

5

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Tom Alber

MolProbity: all-atom contacts and structure validation for proteins and nucleic acids

6

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language of work or name

English

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publication date

3 December 2009

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published in

Nature

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volume

462

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issue

7273

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page(s)

669-73

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cites work

1 reference

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From The Cover: Automated protein crystal structure determination using ELVES

20 March 2017

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Structural insights into the catalytic mechanism of cyclophilin A

20 March 2017

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NMR View: A computer program for the visualization and analysis of NMR data

20 March 2017

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Phasercrystallographic software

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20 March 2017

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PHENIX: building new software for automated crystallographic structure determination

20 March 2017

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Dynamic personalities of proteins

20 March 2017

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The dynamic energy landscape of dihydrofolate reductase catalysis

7 April 2017

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Intrinsic dynamics of an enzyme underlies catalysis

7 April 2017

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Automated electron-density sampling reveals widespread conformational polymorphism in proteins

7 April 2017

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Trapping moving targets with small molecules

29 September 2017

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Protein dynamism and evolvability.

29 September 2017

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Mechanistic insight into the role of transition-state stabilization in cyclophilin A.

29 September 2017

1 reference

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Catalytic mechanism of cyclophilin as observed in molecular dynamics simulations: pathway prediction and reconciliation of X-ray crystallographic and NMR solution data

29 September 2017

1 reference

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Relating protein motion to catalysis

29 September 2017

1 reference

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New tools provide new insights in NMR studies of protein dynamics

29 September 2017

1 reference

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Crystal structures of cyclophilin and its partners

29 September 2017

1 reference

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Biomolecular cryocrystallography: structural changes during flash-cooling

29 September 2017

1 reference

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Enzyme dynamics during catalysis

29 September 2017

1 reference

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Atomic motion in enzymatic reaction coordinates

29 September 2017

1 reference

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Studying excited states of proteins by NMR spectroscopy.

29 September 2017

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A heteronuclear correlation experiment for simultaneous determination of 15N longitudinal decay and chemical exchange rates of systems in slow equilibrium

29 September 2017

1 reference

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Effects of temperature on protein structure and dynamics: X-ray crystallographic studies of the protein ribonuclease-A at nine different temperatures from 98 to 320 K.

29 September 2017

1 reference

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Active site mutants of human cyclophilin A separate peptidyl-prolyl isomerase activity from cyclosporin A binding and calcineurin inhibition

29 September 2017

1 reference

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Temperature-dependent X-ray diffraction as a probe of protein structural dynamics

29 September 2017

1 reference

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Conservation of mus-ms enzyme motions in the apo- and substrate-mimicked state

29 September 2017

1 reference

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Direct measurements of the dissociation-rate constant for inhibitor-enzyme complexes via the T1 rho and T2 (CPMG) methods.

2 June 2018

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Determination of kinetic constants for peptidyl prolyl cis-trans isomerases by an improved spectrophotometric assay

2 June 2018

1 reference

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Observation of decreased radiation damage at higher dose rates in room temperature protein crystallography.

2 June 2018

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Cis/trans isomerization in HIV-1 capsid protein catalyzed by cyclophilin A: insights from computational and theoretical studies

27 November 2018

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What is so special about Arg 55 in the catalysis of cyclophilin A? insights from hybrid QM/MM simulations

27 November 2018

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A TROSY CPMG sequence for characterizing chemical exchange in large proteins

27 November 2018

1 reference

12 December 2020

Crystalline ribonuclease A loses function below the dynamical transition at 220 K

1 reference

12 December 2020

Processing of X-ray diffraction data collected in oscillation mode

1 reference

12 December 2020

Thermal expansion of a protein

1 reference

12 December 2020

The Static Magnetic Field Dependence of Chemical Exchange Linebroadening Defines the NMR Chemical Shift Time Scale

1 reference

https://api.crossref.org/works/10.1038%2FNATURE08615

7 January 2021

A novel free-mounting system for protein crystals: transformation and improvement of diffraction power by accurately controlled humidity changes

1 reference

https://api.crossref.org/works/10.1038%2FNATURE08615

7 January 2021

Automatic processing of rotation diffraction data from crystals of initially unknown symmetry and cell constants

1 reference

https://api.crossref.org/works/10.1038%2FNATURE08615

7 January 2021

PROCHECK: a program to check the stereochemical quality of protein structures

1 reference

https://api.crossref.org/works/10.1038%2FNATURE08615

7 January 2021

Identifiers

DOI

10.1038/NATURE08615

1 reference

Dimensions Publication ID

1033159394

0 references

1 reference

1 reference

PubMed publication ID

19956261

1 reference