Crystal structure of the IL-15-IL-15Ralpha complex, a cytokine-receptor unit presented in trans (Q27646838)

2

0 references

Teruya Nakamura

3

0 references

Sachiko Toma

4

0 references

Tsuyoshi Shuto

5

0 references

Hirofumi Kai

6

0 references

Yuriko Yamagata

7

0 references

Simon J Davis

8

0 references

Shinji Ikemizu

Cloning of a T cell growth factor that interacts with the beta chain of the interleukin-2 receptor

9

0 references

language of work or name

English

0 references

publication date

September 2007

0 references

published in

Nature Immunology

0 references

volume

8

0 references

issue

9

0 references

page(s)

1001-7

0 references

cites work

1 reference

Functional characterization of the human interleukin-15 receptor alpha chain and close linkage of IL15RA and IL2RA genes

21 April 2017

1 reference

IL-15Ralpha recycles and presents IL-15 In trans to neighboring cells

21 April 2017

1 reference

Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene

21 April 2017

1 reference

Interleukin-2 receptor α chain regulates the size and content of the peripheral lymphoid compartment

21 April 2017

1 reference

Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice

21 April 2017

1 reference

Structure of the quaternary complex of interleukin-2 with its alpha, beta, and gammac receptors

21 April 2017

1 reference

PROCHECK: a program to check the stereochemical quality of protein structures

21 April 2017

1 reference

Dali: a network tool for protein structure comparison

21 April 2017

1 reference

Shape complementarity at protein/protein interfaces

21 April 2017

1 reference

Protein-protein recognition: crystal structural analysis of a barnase-barstar complex at 2.0-A resolution

21 April 2017

1 reference

Hexameric structure and assembly of the interleukin-6/IL-6 alpha-receptor/gp130 complex

21 April 2017

1 reference

Coot: model-building tools for molecular graphics

21 April 2017

1 reference

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

21 April 2017

1 reference

PHENIX: building new software for automated crystallographic structure determination

21 April 2017

1 reference

Bi-cycling the furin pathway: from TGN localization to pathogen activation and embryogenesis

21 April 2017

2 references

21 April 2017

The biology of interleukin-2 and interleukin-15: implications for cancer therapy and vaccine design

21 January 2018

1 reference

Common gamma chain cytokines: dissidence in the details

21 January 2018

1 reference

Homeostasis of memory T cells

21 January 2018

1 reference

Diverse functions of IL-2, IL-15, and IL-7 in lymphoid homeostasis

21 January 2018

1 reference

A lymphokine, provisionally designated interleukin T and produced by a human adult T-cell leukemia line, stimulates T-cell proliferation and the induction of lymphokine-activated killer cells

21 January 2018

1 reference

IL-15/IL-15 receptor biology: a guided tour through an expanding universe

21 January 2018

1 reference

Interleukin (IL) 15/IL-T production by the adult T-cell leukemia cell line HuT-102 is associated with a human T-cell lymphotrophic virus type I region /IL-15 fusion message that lacks many upstream AUGs that normally attenuates IL-15 mRNA translatio

21 January 2018

1 reference

Coordinate expression and trans presentation of interleukin (IL)-15Ralpha and IL-15 supports natural killer cell and memory CD8+ T cell homeostasis

21 January 2018

1 reference

T cell-independent interleukin 15Ralpha signals are required for bystander proliferation

21 January 2018

1 reference

Control of homeostasis of CD8+ memory T cells by opposing cytokines.

21 January 2018

1 reference

Interleukin-2 programs mouse alpha beta T lymphocytes for apoptosis

21 January 2018

1 reference

Interleukin-15 protects from lethal apoptosis in vivo.

21 January 2018

1 reference

Role of trans-cellular IL-15 presentation in the activation of NK cell-mediated killing, which leads to enhanced tumor immunosurveillance

21 January 2018

1 reference

Coadministration of HIV vaccine vectors with vaccinia viruses expressing IL-15 but not IL-2 induces long-lasting cellular immunity

21 January 2018

1 reference

Crystal structure of the IL-2 signaling complex: paradigm for a heterotrimeric cytokine receptor

21 January 2018

1 reference

The Sushi domain of soluble IL-15 receptor alpha is essential for binding IL-15 and inhibiting inflammatory and allogenic responses in vitro and in vivo.

21 January 2018

1 reference

Why are proteins O-glycosylated?

21 January 2018

1 reference

Cytoskeletal polarization and redistribution of cell-surface molecules during T cell antigen recognition

21 January 2018

1 reference

IL-15R alpha expression on CD8+ T cells is dispensable for T cell memory

21 January 2018

1 reference

Transregulation of memory CD8 T-cell proliferation by IL-15Rα+ bone marrow–derived cells

21 January 2018

1 reference

Interleukin-2 signals during priming are required for secondary expansion of CD8+ memory T cells.

21 January 2018

1 reference

COMO: a program for combined molecular replacement

21 January 2018

1 reference

Activation requirements for the induction of CD4+CD25+ T cell suppressor function

21 January 2018

1 reference

Immunology. The immunological synapse--a multitasking system

21 January 2018

1 reference

Structural comparisons among the short-chain helical cytokines

21 January 2018

1 reference

Structure-function studies of interleukin 15 using site-specific mutagenesis, polyethylene glycol conjugation, and homology modeling

21 January 2018

1 reference

7 January 2021

Identification and cloning of a novel IL-15 binding protein that is structurally related to the alpha chain of the IL-2 receptor

1 reference

7 January 2021

Soluble interleukin-15 receptor alpha (IL-15R alpha)-sushi as a selective and potent agonist of IL-15 action through IL-15R beta/gamma. Hyperagonist IL-15 x IL-15R alpha fusion proteins

1 reference

7 January 2021

Analysis of the role of the interleukin-2 receptor gamma chain in ligand binding

1 reference

7 January 2021

Deregulated T cell activation and autoimmunity in mice lacking interleukin-2 receptor beta

1 reference

7 January 2021

IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation

1 reference

7 January 2021

The structure of interleukin-2 complexed with its alpha receptor

1 reference

7 January 2021

The structure of the interleukin-15 alpha receptor and its implications for ligand binding

1 reference

7 January 2021

Functional epitope of common gamma chain for interleukin-4 binding

1 reference

7 January 2021

Rapid, electrostatically assisted association of proteins

1 reference

7 January 2021

The immunological synapse: required for T cell receptor signalling or directing T cell effector function?

1 reference

7 January 2021

Processing of X-ray diffraction data collected in oscillation mode

1 reference

7 January 2021

Macromolecular TLS refinement in REFMAC at moderate resolutions

1 reference

7 January 2021