Molecular basis of MAPK-activated protein kinase 2:p38 assembly (Q27644283)

GOA release 2020-03-11

author name string

Andre White

1

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Christopher A Pargellis

2

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Joey M Studts

3

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Brian G Werneburg

4

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Bennett T Farmer

Proceedings of the National Academy of Sciences of the United States of America

5

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language of work or name

English

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publication date

10 April 2007

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published in

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volume

104

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issue

15

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page(s)

6353-8

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cites work

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Identification of a docking groove on ERK and p38 MAP kinases that regulates the specificity of docking interactions

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Leptomycin B-sensitive nuclear export of MAPKAP kinase 2 is regulated by phosphorylation

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A conserved docking motif in MAP kinases common to substrates, activators and regulators

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Mitogen-activated protein kinase-activated protein kinase 2 regulates tumor necrosis factor mRNA stability and translation mainly by altering tristetraprolin expression, stability, and binding to adenine/uridine-rich element

7 April 2017

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Generation and characterization of p38beta (MAPK11) gene-targeted mice.

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Creation of a stress-activated p90 ribosomal S6 kinase. The carboxyl-terminal tail of the MAPK-activated protein kinases dictates the signal transduction pathway in which they function

29 September 2017

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Protein expression of TNF-alpha in psoriatic skin is regulated at a posttranscriptional level by MAPK-activated protein kinase 2.

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Interleukin (IL)-6 signaling leads to phosphorylation of the small heat shock protein (Hsp)27 through activation of the MAP kinase and MAPKAP kinase 2 pathway in monocytes and monocytic leukemia cells.

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Catalysis and function of the p38 alpha.MK2a signaling complex

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Time-resolved Forster resonance energy transfer assays for the binding of nucleotide and protein substrates to p38alpha protein kinase

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High-level expression, activation, and subcellular localization of p38-MAP kinase in thyroid neoplasms

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MAPKAP kinase 2-deficient mice are resistant to collagen-induced arthritis

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Docking interactions induce exposure of activation loop in the MAP kinase ERK2

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