Alpha-factor pheromone receptor STE2 YFL026W (Q27552073)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/D6VTK4

Pheromone alpha factor receptor, double transmembrane domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/D6VTK4

Putative uncharacterized transport proteins

1 reference

Transporter Classification Database ID

9.B.45.1.1

hierarchical database ID heuristic

2 October 2019

based on heuristic

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

found in taxon

Saccharomyces cerevisiae S288c

1 reference

25 May 2022

1 reference

25 May 2022

signal transducer activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=D6VTK4&geneProductId=UniProtKB:D6VTK4

1 reference

24 April 2018

mating-type alpha-factor pheromone receptor activity

The yeast alpha-factor receptor: structural properties deduced from the sequence of the STE2 gene

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D6VTK4

ISS

14 February 2019

Binding of α-factor pheromone to yeast a cells: Chemical and genetic evidence for an α-factor receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D6VTK4

14 February 2019

Dominant-negative mutations in the G-protein-coupled alpha-factor receptor map to the extracellular ends of the transmembrane segments

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D6VTK4

14 February 2019

Dominant-negative mutations in the G-protein-coupled alpha-factor receptor map to the extracellular ends of the transmembrane segments

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D6VTK4

IGI

14 February 2019

Beta and gamma subunits of a yeast guanine nucleotide-binding protein are not essential for membrane association of the alpha subunit but are required for receptor coupling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D6VTK4

mating-type factor pheromone receptor activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D6VTK4

1 reference

14 February 2019

pheromone binding

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D6VTK4

G protein-coupled receptor activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D6VTK4

1 reference

14 February 2019

protein binding

1 reference

14 February 2019

A role for a complex between activated G protein-coupled receptors in yeast cellular mating

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D6VTK4

integral component of plasma membrane

cell component

1 reference

14 February 2019

The STE2 gene product is the ligand-binding component of the alpha-factor receptor of Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D6VTK4

membrane

G protein-coupled receptor homodimeric complex

2 references

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D6VTK4

integral component of membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D6VTK4

1 reference

14 February 2019

biological process

response to pheromone

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D6VTK4

1 reference

14 February 2019

positive regulation of conjugation with cellular fusion

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D6VTK4

signal transduction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D6VTK4

1 reference

14 February 2019

cytogamy

receptor transactivation

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D6VTK4

pheromone-dependent signal transduction involved in conjugation with cellular fusion

1 reference

24 April 2018

Saccharomyces cerevisiae mutants unresponsive to alpha-factor pheromone: alpha-factor binding and extragenic suppression

http://www.ebi.ac.uk/QuickGO/annotations?protein=D6VTK4&geneProductId=UniProtKB:D6VTK4

cell projection assembly

1 reference

14 February 2019

The alpha-factor receptor C-terminus is important for mating projection formation and orientation in Saccharomyces cerevisiae.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D6VTK4

protein homooligomerization

1 reference

14 February 2019

Oligomerization of the yeast alpha-factor receptor: implications for dominant negative effects of mutant receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:D6VTK4

pheromone-dependent signal transduction involved in conjugation with cellular fusion

Identifiers

1 reference

20 March 2022

1 reference

25 May 2022

1 reference

Transporter Classification Database ID

1 reference

20 March 2022

9.B.45.1.1

2 references

Transporter Classification database

13 March 2020

Transporter Classification database