Atg12p YBR217W (Q27549765)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P38316

Ubiquitin-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P38316

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

found in taxon

Saccharomyces cerevisiae S288c

1 reference

25 May 2022

1 reference

25 May 2022

enzyme activator activity

1 reference

14 February 2019

Atg12-Atg5 conjugate enhances E2 activity of Atg3 by rearranging its catalytic site

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38316

Atg8 ligase activity

1 reference

27 February 2018

The Atg12-Atg5 conjugate has a novel E3-like activity for protein lipidation in autophagy

http://www.ebi.ac.uk/QuickGO/annotations?protein=P38316&geneProductId=UniProtKB:P38316

protein tag

3 references

14 February 2019

Apg10p, a novel protein-conjugating enzyme essential for autophagy in yeast.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38316

14 February 2019

A protein conjugation system essential for autophagy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38316

14 February 2019

Apg7p/Cvt2p: A novel protein-activating enzyme essential for autophagy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38316

protein binding

7 references

14 February 2019

Mechanism and functions of membrane binding by the Atg5-Atg12/Atg16 complex during autophagosome formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38316

14 February 2019

A comprehensive two-hybrid analysis to explore the yeast protein interactome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38316

14 February 2019

Structure of the Atg12–Atg5 conjugate reveals a platform for stimulating Atg8–PE conjugation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38316

14 February 2019

Apg16p is required for the function of the Apg12p-Apg5p conjugate in the yeast autophagy pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38316

14 February 2019

Assigning function to yeast proteins by integration of technologies.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38316

14 February 2019

A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38316

14 February 2019

A protein conjugation system essential for autophagy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38316

Atg8 ligase activity

cell component

phagophore assembly site

IC

1 reference

14 February 2019

Formation of the approximately 350-kDa Apg12-Apg5.Apg16 multimeric complex, mediated by Apg16 oligomerization, is essential for autophagy in yeast

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38316

IC

cytoplasm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38316

1 reference

14 February 2019

membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38316

1 reference

14 February 2019

Atg12-Atg5-Atg16 complex

1 reference

27 February 2018

Formation of the approximately 350-kDa Apg12-Apg5.Apg16 multimeric complex, mediated by Apg16 oligomerization, is essential for autophagy in yeast

http://www.ebi.ac.uk/QuickGO/annotations?protein=P38316&geneProductId=UniProtKB:P38316

Atg12-Atg5-Atg16 complex

cytosol

HDA

1 reference

14 February 2019

One library to make them all: streamlining the creation of yeast libraries via a SWAp-Tag strategy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38316

HDA

biological process

autophagy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38316

1 reference

14 February 2019

autophagy of mitochondrion

1 reference

27 February 2018

A genomic screen for yeast mutants defective in selective mitochondria autophagy

http://www.ebi.ac.uk/QuickGO/annotations?protein=P38316&geneProductId=UniProtKB:P38316

C-terminal protein lipidation

1 reference

27 February 2018

The Atg12-Atg5 conjugate has a novel E3-like activity for protein lipidation in autophagy

http://www.ebi.ac.uk/QuickGO/annotations?protein=P38316&geneProductId=UniProtKB:P38316

piecemeal microautophagy of the nucleus

1 reference

14 February 2019

Piecemeal microautophagy of the nucleus requires the core macroautophagy genes.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38316

protein transport

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38316

1 reference

14 February 2019

cytoplasm to vacuole transport by the Cvt pathway

1 reference

14 February 2019

A protein conjugation system essential for autophagy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38316

late nucleophagy

1 reference

14 February 2019

A late form of nucleophagy in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38316

positive regulation of catalytic activity

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38316

protein lipidation involved in autophagosome assembly

1 reference

14 February 2019

Molecular mechanism of autophagic membrane-scaffold assembly and disassembly

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38316

autophagosome assembly

Structure-function relationship of Atg12, a ubiquitin-like modifier essential for autophagy

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38316

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38316

14 February 2019

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P38316

autophagy of mitochondrion

C-terminal protein lipidation

Identifiers

1 reference

20 March 2022

1 reference

25 May 2022

1 reference