Vinculin controls talin engagement with the actomyosin machinery. (Q27342876)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26634421%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

title

Vinculin controls talin engagement with the actomyosin machinery (English)

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1 March 2020

1

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1 March 2020

Benjamin Stutchbury

2

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1 March 2020

Benjamin T Goult

11

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1 March 2020

Christoph Ballestrem

13

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1 March 2020

author name string

De-Yao Wang

3

1 reference

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1 March 2020

Devina Jethwa

4

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1 March 2020

Ricky Tsang

5

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1 March 2020

Eugenia Meiler-Rodriguez

6

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1 March 2020

Pengbo Wang

7

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1 March 2020

Neil Bate

8

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1 March 2020

Roy Zent

9

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1 March 2020

Igor L Barsukov

10

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1 March 2020

David R Critchley

12

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1 March 2020

language of work or name

English

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publication date

4 December 2015

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26634421%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

published in

Nature Communications

1 reference

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1 March 2020

volume

6

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1 March 2020

page(s)

10038

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Creative Commons Attribution 4.0 International

1 March 2020

copyright license

start time

1 December 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4686655/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Talin Dependent Mechanosensitivity of Cell Focal Adhesions

1 reference

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RIAM and Vinculin Binding to Talin Are Mutually Exclusive and Regulate Adhesion Assembly and Turnover

21 March 2017

1 reference

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Integrins β1 and β3 exhibit distinct dynamic nanoscale organizations inside focal adhesions

21 March 2017

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FAK promotes recruitment of talin to nascent adhesions to control cell motility

21 March 2017

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Phosphoinositide signaling regulates the exocyst complex and polarized integrin trafficking in directionally migrating cells

21 March 2017

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Central Region of Talin Has a Unique Fold That Binds Vinculin and Actin

21 March 2017

1 reference

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The Structure of an Interdomain Complex That Regulates Talin Activity

21 March 2017

1 reference

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The structure of the C-terminal actin-binding domain of talin

21 March 2017

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Activation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundle

21 March 2017

1 reference

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Focal contacts as mechanosensors: externally applied local mechanical force induces growth of focal contacts by an mDia1-dependent and ROCK-independent mechanism

21 March 2017

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Conformation, localization, and integrin binding of talin depend on its interaction with phosphoinositides

21 March 2017

1 reference

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Mice carrying a complete deletion of the talin2 coding sequence are viable and fertile

21 March 2017

1 reference

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RIAM, an Ena/VASP and Profilin ligand, interacts with Rap1-GTP and mediates Rap1-induced adhesion

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686655

Stretching single talin rod molecules activates vinculin binding

21 March 2017

1 reference

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Talin Binding to Integrin ß Tails: A Final Common Step in Integrin Activation

7 April 2017

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Cell locomotion and focal adhesions are regulated by substrate flexibility

7 April 2017

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Talin determines the nanoscale architecture of focal adhesions

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686655

Alternative mechanisms for talin to mediate integrin function

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686655

Lipid binding promotes oligomerization and focal adhesion activity of vinculin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686655

Vinculin-dependent actin bundling regulates cell migration and traction forces.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686655

Integrin-associated complexes form hierarchically with variable stoichiometry in nascent adhesions

29 September 2017

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Mechanical activation of vinculin binding to talin locks talin in an unfolded conformation

29 September 2017

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Force-dependent vinculin binding to talin in live cells: a crucial step in anchoring the actin cytoskeleton to focal adhesions

29 September 2017

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Actomyosin-dependent formation of the mechanosensitive talin-vinculin complex reinforces actin anchoring

29 September 2017

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Micropatterning cell adhesion on polyacrylamide hydrogels

29 September 2017

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Talins and kindlins: partners in integrin-mediated adhesion.

29 September 2017

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Vinculin-actin interaction couples actin retrograde flow to focal adhesions, but is dispensable for focal adhesion growth.

29 September 2017

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Structural studies on full-length talin1 reveal a compact auto-inhibited dimer: implications for talin activation

29 September 2017

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How vinculin regulates force transmission

29 September 2017

1 reference

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Two modes of integrin activation form a binary molecular switch in adhesion maturation

29 September 2017

1 reference

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Vinculin regulates the recruitment and release of core focal adhesion proteins in a force-dependent manner

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686655

Assembly and disassembly of cell matrix adhesions

29 September 2017

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Finding the weakest link: exploring integrin-mediated mechanical molecular pathways

29 September 2017

1 reference

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Subcellular localization of talin is regulated by inter-domain interactions

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686655

Strength in the periphery: growth cone biomechanics and substrate rigidity response in peripheral and central nervous system neurons

29 September 2017

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New isoform-specific monoclonal antibodies reveal different sub-cellular localisations for talin1 and talin2.

29 September 2017

1 reference

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The Vinculin C-terminal Hairpin Mediates F-actin Bundle Formation, Focal Adhesion, and Cell Mechanical Properties

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686655

The C terminus of talin links integrins to cell cycle progression.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686655

Fluorescence recovery after photobleaching.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686655

Regulation of Integrin Activation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686655

Vinculin, an adapter protein in control of cell adhesion signalling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686655

Mechanical integration of actin and adhesion dynamics in cell migration

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686655

Control of high affinity interactions in the talin C terminus: how talin domains coordinate protein dynamics in cell adhesions.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686655

Talin depletion reveals independence of initial cell spreading from integrin activation and traction

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686655

Vinculin controls focal adhesion formation by direct interactions with talin and actin.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686655

Structural basis of filamin A functions

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686655

The integrin binding site 2 (IBS2) in the talin rod domain is essential for linking integrin beta subunits to the cytoskeleton

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686655

Polymerizing actin fibers position integrins primed to probe for adhesion sites

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686655

The structure and regulation of vinculin.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686655

Assembly and mechanosensory function of focal adhesions: experiments and models.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686655

Two distinct head-tail interfaces cooperate to suppress activation of vinculin by talin.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686655

FRAP analysis of binding: proper and fitting

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686655

Talin1 is critical for force-dependent reinforcement of initial integrin-cytoskeleton bonds but not tyrosine kinase activation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686655

Marching at the front and dragging behind: differential alphaVbeta3-integrin turnover regulates focal adhesion behavior

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686655

Analysis of the mammalian talin2 gene TLN2.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686655

The Talin head domain binds to integrin beta subunit cytoplasmic tails and regulates integrin activation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686655

Talin contains three actin-binding sites each of which is adjacent to a vinculin-binding site

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686655

Targeted disruption of vinculin genes in F9 and embryonic stem cells changes cell morphology, adhesion, and locomotion

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686655

Regulation of vinculin binding to talin and actin by phosphatidyl-inositol-4-5-bisphosphate

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686655

Characteristics of papillary collecting duct cells in primary culture.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4686655

Mapping and consensus sequence identification for multiple vinculin binding sites within the talin rod.

2 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCOMMS10038

Early molecular events in the assembly of matrix adhesions at the leading edge of migrating cells.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCOMMS10038

Role of vinculin in regulating focal adhesion turnover

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26634421

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Purification of muscle actin

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26634421

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NCOMMS10038

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26634421%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

1 March 2020

ADS bibcode

2015NatCo...610038A

0 references

1028042418

0 references

OpenCitations bibliographic resource ID

1192474

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1192474

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26634421%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

PubMed publication ID

26634421

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26634421%20AND%20SRC:MED&resulttype=core&format=json