Allosteric regulation of serine protease HtrA2 through novel non-canonical substrate binding pocket (Q27316788)

23 June 2017

title

Allosteric regulation of serine protease HtrA2 through novel non-canonical substrate binding pocket (English)

1 reference

23 June 2017

1 reference

Pruthvi Raj Bejugam

1

1 reference

23 June 2017

Raja R Kuppili

2

1 reference

23 June 2017

Nitu Singh

3

1 reference

23 June 2017

Nikhil Gadewal

4

1 reference

23 June 2017

Lalith K Chaganti

5

1 reference

23 June 2017

G Madhavi Sastry

6

1 reference

23 June 2017

Kakoli Bose

7

1 reference

23 June 2017

language of work or name

English

0 references

publication date

14 February 2013

1 reference

23 June 2017

1 reference

23 June 2017

volume

8

1 reference

23 June 2017

issue

2

1 reference

23 June 2017

page(s)

e55416

1 reference

Creative Commons Attribution 4.0 International

23 June 2017

copyright license

start time

14 February 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Allostery Is an Intrinsic Property of the Protease Domain of DegS: IMPLICATIONS FOR ENZYME FUNCTION AND EVOLUTION

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573033

Structural and functional analysis of the PDZ domains of human HtrA1 and HtrA3

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573033

PDZ7 of glutamate receptor interacting protein binds to its target via a novel hydrophobic surface area

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573033

Structural insights into the pro-apoptotic function of mitochondrial serine protease HtrA2/Omi

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573033

HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573033

The serine protease Omi/HtrA2 regulates apoptosis by binding XIAP through a reaper-like motif

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573033

Expression, purification, and functional analysis of the human serine protease HtrA2

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573033

21 March 2017

The Protein Data Bank

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573033

GROMACS: fast, flexible, and free

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573033

Mitochondrial protease Omi/HtrA2 enhances caspase activation through multiple pathways

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573033

PDZ domains: structural modules for protein complex assembly

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573033

Omi/HtrA2 promotes cell death by binding and degrading the anti-apoptotic protein ped/pea-15

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573033

Glide: a new approach for rapid, accurate docking and scoring. 1. Method and assessment of docking accuracy

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573033

PDZ domains - common players in the cell signaling

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573033

Serine Proteases: Structure and Mechanism of Catalysis

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573033

Extra precision glide: docking and scoring incorporating a model of hydrophobic enclosure for protein-ligand complexes

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573033

Glide: a new approach for rapid, accurate docking and scoring. 2. Enrichment factors in database screening

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573033

The structural basis of mode of activation and functional diversity: a case study with HtrA family of serine proteases

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573033

Overexpression of cIAP2 contributes to 5-FU resistance and a poor prognosis in oral squamous cell carcinoma

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573033

Dynamic allostery: linkers are not merely flexible

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573033

Novel variant Pro143Ala in HTRA2 contributes to Parkinson's disease by inducing hyperphosphorylation of HTRA2 protein in mitochondria.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573033

Novel mitochondrial substrates of omi indicate a new regulatory role in neurodegenerative disorders

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573033

A new function of human HtrA2 as an amyloid-beta oligomerization inhibitor

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573033

Growth inhibition of breast cancer cell line MCF-7 by siRNA silencing of Wilms tumor 1 gene.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573033

Rapid characterization of the binding property of HtrA2/Omi PDZ domain by validation screening of PDZ ligand library

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573033

The homotrimeric structure of HtrA2 is indispensable for executing its serine protease activity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573033

Novel procedure for modeling ligand/receptor induced fit effects.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573033

G-protein-coupled receptor allosterism: the promise and the problem(s).

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573033

Binding specificity and regulation of the serine protease and PDZ domains of HtrA2/Omi

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573033

A method for computational combinatorial peptide design of inhibitors of Ras protein

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573033

Fluorescein isothiocyanate-labeled casein assay for proteolytic enzymes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573033

Lysine-sensitive aspartokinase of Escherichia coli K12. Synergy and autosynergy in an allosteric V system

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573033

High-energy water sites determine peptide binding affinity and specificity of PDZ domains

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573033

OMP peptides modulate the activity of DegS protease by differential binding to active and inactive conformations.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3573033

Determinants of structural and functional plasticity of a widely conserved protease chaperone complex

31 May 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0055416

Structural and functional analysis of the ligand specificity of the HtrA2/Omi PDZ domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0055416

Allosteric Modulation of G Protein–Coupled Receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0055416

Comparison of simple potential functions for simulating liquid water

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0055416

Efficient site-specific processing of fusion proteins by tobacco vein mottling virus protease in vivo and in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0055416

Study of survivin and X-linked inhibitor of apoptosis protein (XIAP) genes in acute myeloid leukemia (AML)

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23457469

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Wilms tumor gene (WT1) as a new marker for the detection of minimal residual disease in leukemia

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23457469

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

New method for fast and accurate binding-site identification and analysis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23457469

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0055416

1 reference

release_lzty3w744ramxdfucohbr7jovy

23 June 2017

0 references

0 references

OpenCitations bibliographic resource ID

3847552

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

3847552

1 reference