Peptidylarginine deiminase and protein citrullination in prion diseases: strong evidence of neurodegeneration (Q27023431)

Akihito Ishigami

2

1 reference

Naoki Maruyama

3

1 reference

Yong-Sun Kim

5

1 reference

Eun-Kyoung Choi

6

1 reference

language of work or name

1 reference

2013

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1 reference

7

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issue

1

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page(s)

42-6

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The role of citrullinated proteins suggests a novel mechanism in the pathogenesis of multiple sclerosis

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PAD, a growing family of citrullinating enzymes: genes, features and involvement in disease

21 March 2017

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Human PAD4 regulates histone arginine methylation levels via demethylimination

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Structural basis for Ca(2+)-induced activation of human PAD4

21 March 2017

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ePAD, an oocyte and early embryo-abundant peptidylarginine deiminase-like protein that localizes to egg cytoplasmic sheets

21 March 2017

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Role for PADI6 and the cytoplasmic lattices in ribosomal storage in oocytes and translational control in the early mouse embryo

21 March 2017

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Peptidylarginine deiminase (PAD) 6 is essential for oocyte cytoskeletal sheet formation and female fertility

21 March 2017

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Sporadic human prion diseases: molecular insights and diagnosis

21 March 2017

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Induction of osteoclastogenesis and bone loss by human autoantibodies against citrullinated vimentin

28 September 2017

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Peptidylarginine deiminase 2, 3 and 4 have distinct specificities against cellular substrates: novel insights into autoantigen selection in rheumatoid arthritis

28 September 2017

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Protein deiminases: new players in the developmentally regulated loss of neural regenerative ability.

28 September 2017

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Subcellular Localization of Peptidylarginine Deiminase 2 and Citrullinated Proteins in Brains of Scrapie-Infected Mice: Nuclear Localization of PAD2 and Membrane Fraction-Enriched Citrullinated Proteins

28 September 2017

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Regulation of mouse oocyte microtubule and organelle dynamics by PADI6 and the cytoplasmic lattices

28 September 2017

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PAD4 is essential for antibacterial innate immunity mediated by neutrophil extracellular traps

28 September 2017

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Substrate specificity and kinetic studies of PADs 1, 3, and 4 identify potent and selective inhibitors of protein arginine deiminase 3.

28 September 2017

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Coordination of PAD4 and HDAC2 in the regulation of p53-target gene expression

28 September 2017

1 reference

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Involvement of peptidylarginine deiminase-mediated post-translational citrullination in pathogenesis of sporadic Creutzfeldt-Jakob disease

28 September 2017

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Multifunctional roles of enolase in Alzheimer's disease brain: beyond altered glucose metabolism

28 September 2017

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Increased PADI4 expression in blood and tissues of patients with malignant tumors

28 September 2017

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Histone hypercitrullination mediates chromatin decondensation and neutrophil extracellular trap formation.

28 September 2017

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Peptidylarginine deiminase 2 (PAD2) overexpression in transgenic mice leads to myelin loss in the central nervous system

28 September 2017

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Accumulation of citrullinated proteins by up-regulated peptidylarginine deiminase 2 in brains of scrapie-infected mice: a possible role in pathogenesis

28 September 2017

1 reference

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Calpain-mediated signaling mechanisms in neuronal injury and neurodegeneration

28 September 2017

1 reference

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Regulation of p53 target gene expression by peptidylarginine deiminase 4

28 September 2017

1 reference

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Histone Arg modifications and p53 regulate the expression of OKL38, a mediator of apoptosis

28 September 2017

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Update on peptidylarginine deiminases and deimination in skin physiology and severe human diseases.

28 September 2017

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Molecular mechanisms of prion pathogenesis

28 September 2017

1 reference

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Immunity to citrullinated proteins in rheumatoid arthritis

28 September 2017

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Astrocyte calcium waves: what they are and what they do.

28 September 2017

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Astrocyte calcium elevations: properties, propagation, and effects on brain signaling

28 September 2017

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Proteomics implicates peptidyl arginine deiminase 2 and optic nerve citrullination in glaucoma pathogenesis

28 September 2017

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The peptidylarginine deiminases expressed in human epidermis differ in their substrate specificities and subcellular locations.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609049

Abnormal accumulation of citrullinated proteins catalyzed by peptidylarginine deiminase in hippocampal extracts from patients with Alzheimer's disease.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609049

Peptidylarginine deiminase isoforms 1-3 are expressed in the epidermis and involved in the deimination of K1 and filaggrin.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609049

Increased citrullinated glial fibrillary acidic protein in secondary progressive multiple sclerosis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609049

The role of an enolase-related molecule in plasminogen binding to cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609049

Myelin in multiple sclerosis is developmentally immature

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609049

The expression of PADI4 in synovium of rheumatoid arthritis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609049

Regulation of the expression of peptidylarginine deiminase type II gene (PADI2) in human keratinocytes involves Sp1 and Sp3 transcription factors.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609049

Peptidylarginine deiminase isoforms are differentially expressed in the anagen hair follicles and other human skin appendages

31 May 2018

1 reference

Peptidylarginine deiminase: a candidate factor in demyelinating disease

21 January 2018

1 reference

Dual immunofluorescence study of citrullinated proteins in Parkinson diseased substantia nigra

21 January 2018

1 reference

Deimination of myelin basic protein. 1. Effect of deimination of arginyl residues of myelin basic protein on its structure and susceptibility to digestion by cathepsin D.

21 January 2018

1 reference

21 January 2018

1 reference

Peptidyl arginine deiminase type 2 (PAD-2) and PAD-4 but not PAD-1, PAD-3, and PAD-6 are expressed in rheumatoid arthritis synovium in close association with tissue inflammation

21 January 2018

1 reference

Expression and citrullination of keratin in synovial tissue of rheumatoid arthritis

21 January 2018

1 reference

Peptidylarginine deiminase modulates the physiological roles of enolase via citrullination: links between altered multifunction of enolase and neurodegenerative diseases

21 January 2018

1 reference

Effect of enzymatic deimination on the conformation of recombinant prion protein

21 January 2018

1 reference

Marburg's Variant of Multiple Sclerosis Correlates with a Less Compact Structure of Myelin Basic Protein

21 January 2018

1 reference

Developmental and age-related changes of peptidylarginine deiminase 2 in the mouse brain

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609049

Regulation of histone modification and chromatin structure by the p53–PADI4 pathway

28 November 2018

1 reference

12 December 2020

Ca2+-dependent deimination-induced disassembly of intermediate filaments involves specific modification of the amino-terminal head domain

1 reference

12 December 2020

Acute multiple sclerosis (Marburg type) is associated with developmentally immature myelin basic protein

1 reference

12 December 2020

Enolase-1 promotes plasminogen-mediated recruitment of monocytes to the acutely inflamed lung

1 reference

12 December 2020

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Identifiers

DOI

10.4161/PRI.22380

0 references

Fatcat ID

0 references

1 reference

PubMed publication ID

23022892

1 reference