The redox biology of schistosome parasites and applications for drug development (Q26829701)

Rigouin C

series ordinal

2

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Williams DL

series ordinal

3

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language of work or name

1 reference

2012

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Current Pharmaceutical Design

published in

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volume

18

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issue

24

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page(s)

3595-611

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Colorectal carcinoma associated with schistosomiasis: a possible causal relationship

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Identification of oxadiazoles as new drug leads for the control of schistosomiasis

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Mapping the Catalytic Cycle of Schistosoma mansoni Thioredoxin Glutathione Reductase by X-ray Crystallography

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Glutathione reductase and thioredoxin reductase at the crossroad: the structure of Schistosoma mansoni thioredoxin glutathione reductase

7 April 2017

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Peroxiredoxin evolution and the regulation of hydrogen peroxide signaling

7 April 2017

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Crystal structures of reduced, oxidized, and mutated human thioredoxins: evidence for a regulatory homodimer

7 April 2017

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Crystal structures of a schistosomal drug and vaccine target: glutathione S-transferase from Schistosoma japonica and its complex with the leading antischistosomal drug praziquantel

7 April 2017

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Two enzymes in one; two yeast peroxiredoxins display oxidative stress-dependent switching from a peroxidase to a molecular chaperone function

7 April 2017

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Thioredoxin-dependent peroxide reductase from yeast

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Structure, mechanism and regulation of peroxiredoxins

7 April 2017

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Peroxiredoxin, a novel family of peroxidases

7 April 2017

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Comparison of the decameric structure of peroxiredoxin-II by transmission electron microscopy and X-ray crystallography

7 April 2017

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A new pathway for heavy metal detoxification in animals. Phytochelatin synthase is required for cadmium tolerance in Caenorhabditis elegans

7 April 2017

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Substitution of the thioredoxin system for glutathione reductase in Drosophila melanogaster

7 April 2017

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Thioredoxin glutathione reductase from Schistosoma mansoni: an essential parasite enzyme and a key drug target

7 April 2017

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7 April 2017

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Inhibition by metrifonate and dichlorvos of cholinesterases in schistosomes

7 April 2017

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Clinical pharmacology in normal volunteers of praziquantel, a new drug against schistosomes and cestodes. An example of a complex study covering both tolerance and pharmacokinetics

7 April 2017

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Characterization of the Phytochelatin Synthase of Schistosoma mansoni

7 April 2017

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Quantitative high-throughput screen identifies inhibitors of the Schistosoma mansoni redox cascade

7 April 2017

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Characterization of mouse endoplasmic reticulum methionine-R-sulfoxide reductase

7 April 2017

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The mammalian cytosolic selenoenzyme thioredoxin reductase reduces ubiquinone. A novel mechanism for defense against oxidative stress

7 April 2017

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Selenoprotein oxidoreductase with specificity for thioredoxin and glutathione systems

7 April 2017

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Schistosomiasis and water resources development: systematic review, meta-analysis, and estimates of people at risk

7 April 2017

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Free radicals, metals and antioxidants in oxidative stress-induced cancer

7 April 2017

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7 April 2017

Glutathione transferases

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Reactive oxygen species, antioxidants, and the mammalian thioredoxin system

7 April 2017

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7 April 2017

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7 April 2017

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Investigations of the Catalytic Mechanism of Thioredoxin Glutathione Reductase from Schistosoma mansoni

28 September 2017

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Glutathione revisited: a vital function in iron metabolism and ancillary role in thiol-redox control.

28 September 2017

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Whole mount in situ hybridization methodology for Schistosoma mansoni

28 September 2017

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Hydrogen peroxide as a signaling molecule

28 September 2017

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28 September 2017

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28 September 2017

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Linked thioredoxin-glutathione systems in platyhelminth parasites: alternative pathways for glutathione reduction and deglutathionylation.

28 September 2017

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Praziquantel and schistosomiasis.

28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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Characterization of the methionine sulfoxide reductases of Schistosoma mansoni

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28 September 2017

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Phytochelatins: peptides involved in heavy metal detoxification

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28 September 2017

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Praziquantel: mechanisms of action, resistance and new derivatives for schistosomiasis

28 September 2017

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A 1,536-well-based kinetic HTS assay for inhibitors of Schistosoma mansoni thioredoxin glutathione reductase

28 September 2017

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The synergistic effect of concomitant schistosomiasis, hookworm, and trichuris infections on children's anemia burden

28 September 2017

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28 September 2017

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Platyhelminth mitochondrial and cytosolic redox homeostasis is controlled by a single thioredoxin glutathione reductase and dependent on selenium and glutathione.

28 September 2017

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The unacknowledged impact of chronic schistosomiasis

28 September 2017

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28 September 2017

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Pumping iron: a potential target for novel therapeutics against schistosomes

28 September 2017

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28 September 2017

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Below the belt: new insights into potential complications of HIV-1/schistosome coinfections

28 September 2017

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Chemotherapy of schistosomiasis: present and future

28 September 2017

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Targeting thioredoxin reductase is a basis for cancer therapy by arsenic trioxide

28 September 2017

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Tracking the fate of iron in early development of human blood flukes

28 September 2017

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Seleno-independent glutathione peroxidases. More than simple antioxidant scavengers.

28 September 2017

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Artemisinins for schistosomiasis and beyond.

28 September 2017

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The schistosome enzyme that activates oxamniquine has the characteristics of a sulfotransferase

28 September 2017

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Enzymatic and nonenzymatic synthesis of glutathione conjugates: application to the understanding of a parasite's defense system and alternative to the discovery of potent glutathione S-transferase inhibitors

28 September 2017

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Quantitative high-throughput screening: a titration-based approach that efficiently identifies biological activities in large chemical libraries

28 September 2017

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2-Cys peroxiredoxins from Schistosoma japonicum: the expression profile and localization in the life cycle

28 September 2017

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Antischistosomal efficacy of artesunate combination therapies administered as curative treatments for malaria attacks

28 September 2017

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Schistosomiasis--a century searching for chemotherapeutic drugs.

28 September 2017

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New perspectives on host-parasite interplay by comparative transcriptomic and proteomic analyses of Schistosoma japonicum

28 September 2017

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A papain-like enzyme at work: native and acyl-enzyme intermediate structures in phytochelatin synthesis.

28 September 2017

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Design of potent inhibitors for Schistosoma japonica glutathione S-transferase

28 September 2017

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Superoxide dismutases and their impact upon human health

28 September 2017

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Oxidative stress-dependent structural and functional switching of a human 2-Cys peroxiredoxin isotype II that enhances HeLa cell resistance to H2O2-induced cell death.

28 September 2017

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Roles of methionine suldfoxide reductases in antioxidant defense, protein regulation and survival

28 September 2017

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The chemistry and biology of inhibitors and pro-drugs targeted to glutathione S-transferases

28 September 2017

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Schistosomes: the road from host-parasite interactions to vaccines in clinical trials

28 September 2017

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Vaccination with antioxidant enzymes confers protective immunity against challenge infection with Schistosoma mansoni.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Xenobiotic metabolism in helminths

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Helminth anti-oxidant enzymes: a protective mechanism against host oxidants?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Nucleic acid vaccination with Schistosoma mansoni antioxidant enzyme cytosolic superoxide dismutase and the structural protein filamin confers protection against the adult worm stage

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Weeds, worms, and more. Papain's long-lost cousin, phytochelatin synthase.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Linked thioredoxin-glutathione systems in platyhelminths

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Cross-reactivity of Schistosoma mansoni cytosolic superoxide dismutase, a protective vaccine candidate, with host superoxide dismutase and identification of parasite-specific B epitopes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Characterization of phytochelatin synthase-like protein encoded by alr0975 from a prokaryote, Nostoc sp. PCC 7120.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

The thioredoxin system—From science to clinic

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Pivotal roles of the parasite PGD2 synthase and of the host D prostanoid receptor 1 in schistosome immune evasion

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Redox potential of human thioredoxin 1 and identification of a second dithiol/disulfide motif

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Reversing the Inactivation of Peroxiredoxins Caused by Cysteine Sulfinic Acid Formation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Phytochelatins and metallothioneins: roles in heavy metal detoxification and homeostasis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Reaction mechanism, evolutionary analysis, and role of zinc in Drosophila methionine-R-sulfoxide reductase

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Chemotherapeutic approaches to schistosomes: current knowledge and outlook

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

The disulfide redox system of Schistosoma mansoni and the importance of a multifunctional enzyme, thioredoxin glutathione reductase

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

The potential of artemether for the control of schistosomiasis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Schistosome calcium channel beta subunits. Unusual modulatory effects and potential role in the action of the antischistosomal drug praziquantel

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Schistosome infection stimulates host CD4(+) T helper cell and B-cell responses against a novel egg antigen, thioredoxin peroxidase

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Oral artemether for prevention of Schistosoma mansoni infection: randomised controlled trial

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Gene expression and the thiol redox state

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

The putative gamma-glutamylcysteine synthetase from Plasmodium falciparum contains large insertions and a variable tandem repeat

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Relationship of Impairment of Schistosome 28-Kilodalton GlutathioneS-Transferase (GST) Activity to Expression of Immunity toSchistosoma mattheeiin Calves Vaccinated with RecombinantSchistosoma bovis28-Kilodalton GST

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Expression and characterization of glutathione peroxidase activity in the human blood fluke Schistosoma mansoni

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Antischistosomal drugs: past, present ... and future?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Schistosoma mansoni: cloning and characterization of a gene encoding cytosolic Cu/Zn superoxide dismutase

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Parasite infection and cancer: with special emphasis on Schistosoma japonicum infections (Trematoda). A review

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Inhibition of glutathione synthesis as a chemotherapeutic strategy for trypanosomiasis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Reductive metabolism of niridazole by adult Schistosoma mansoni. Correlation with covalent drug binding to parasite macromolecules.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Immunity to schistosomes: progress toward vaccine

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Drug resistance in schistosomiasis: a review

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Molecular cloning and tissue distribution of a 26-kilodalton Schistosoma mansoni glutathione S-transferase

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Glutathione transferase in helminths

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Antibody response of Schistosoma mansoni-infected human subjects to the recombinant P28 glutathione-S-transferase and to synthetic peptides

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Identification and purification of a second form of Cu/Zn superoxide dismutase from Schistosoma mansoni

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Heavy metal detoxification in higher plants--a review

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

X-ray structure of glutathione S-transferase from Schistosoma japonicum in a new crystal form reveals flexibility of the substrate-binding site

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Redox regulatory and anti-apoptotic functions of thioredoxin depend on S-nitrosylation at cysteine 69.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Inhibition of the peroxidative degradation of haem as the basis of action of chloroquine and other quinoline antimalarials

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Role of glutathione in the detoxification of ferriprotoporphyrin IX in chloroquine resistant Plasmodium berghei

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Parasite sulphur amino acid metabolism

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Schistosoma mansoni: the developmental regulation and immunolocalization of antioxidant enzymes

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

A selenium-containing phospholipid-hydroperoxide glutathione peroxidase in Schistosoma mansoni

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

IgA antibodies to a protective antigen in human Schistosomiasis mansoni

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Schistosoma mansoni: genetic complementation analysis shows that two independent hycanthone/oxamniquine-resistant strains are mutated in the same gene.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Schistosoma mansoni: A Cu/Zn Superoxide Dismutase Is Glycosylated When Expressed in Mammalian Cells and Localizes to a Subtegumental Region in Adult Schistosomes

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Hycanthone: a frameshift mutagen

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

The non-protein thiol of rat liver mitochondria

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Tolerance of Kenyan Schistosoma mansoni to oxamniquine.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

The possible absence of cytochrome P-450 linked xenobiotic metabolism in helminths

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Schistosoma mansoni: levels of antioxidants and resistance to oxidants increase during development.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Schistosoma mansoni: glutathione S-transferase-catalyzed detoxication of dichlorvos

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Another 26-kilodalton glutathioneS-transferase ofSchistosoma mansoni

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Schistosoma mansoni: Single-step purification and characterization of glutathione S-transferase isoenzyme 4

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Molecular cloning and sequencing of glutathione peroxidase from Schistosoma mansoni

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Molecular cloning of a 16-kilodalton Cu/Zn superoxide dismutase from Schistosoma mansoni

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Inter-species variation of schistosome 28-kDa glutathione S-transferases

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Schistosoma mansoni: hycanthone/oxamniquine resistance is controlled by a single autosomal recessive gene

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Hycanthone resistance in schistosomes correlates with the lack of an enzymatic activity which produces the covalent binding of hycanthone to parasite macromolecules.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Efficacy of artesunate with sulfalene plus pyrimethamine versus praziquantel for treatment of Schistosoma mansoni in Kenyan children: an open-label randomised controlled trial

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Dissection of glutathione conjugate turnover in yeast

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Comparative modeling of thioredoxin glutathione reductase from Schistosoma mansoni: a multifunctional target for antischistosomal therapy

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Peroxiredoxin-1 from Schistosoma japonicum functions as a scavenger against hydrogen peroxide but not nitric oxide

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Schistosoma mansoni: lack of correlation between praziquantel-induced intra-worm calcium influx and parasite death

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

The anti-schistosomal drug praziquantel is an adenosine antagonist

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Probing the Mechanism of GSH Activation in Schistosoma haematobium Glutathione-S-transferase by Site-directed Mutagenesis and X-ray Crystallography

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Redox balance mechanisms in Schistosoma mansoni rely on peroxiredoxins and albumin and implicate peroxiredoxins as novel drug targets

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Reaction mechanism and regulation of mammalian thioredoxin/glutathione reductase

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Inhibition of thioredoxin reductase but not of glutathione reductase by the major classes of alkylating and platinum-containing anticancer compounds.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Mammalian selenoprotein thioredoxin-glutathione reductase. Roles in disulfide bond formation and sperm maturation

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Schistosomiasis co-infection in humans influences inflammatory markers in uncomplicated Plasmodium falciparum malaria

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Biochemical characterization of 2-Cys peroxiredoxins from Schistosoma mansoni

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

In vitro effect of low concentrations of oltipraz on the antioxidant defence of mouse hepatocytes and Schistosoma mansoni worms

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Mitochondrial thioredoxin reductase inhibition by gold(I) compounds and concurrent stimulation of permeability transition and release of cytochrome c.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Purification, characterization and kinetic properties of the multifunctional thioredoxin-glutathione reductase from Taenia crassiceps metacestode (cysticerci).

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Specific sites in the Beta Interaction Domain of a schistosome Ca2+ channel beta subunit are key to its role in sensitivity to the anti-schistosomal drug praziquantel

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Thioredoxin reductase from the malaria mosquito Anopheles gambiae

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Interactions of quinones with thioredoxin reductase: a challenge to the antioxidant role of the mammalian selenoprotein

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Protection against Schistosoma mansoni utilizing DNA vaccination with genes encoding Cu/Zn cytosolic superoxide dismutase, signal peptide-containing superoxide dismutase and glutathione peroxidase enzymes

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Schistosoma japonicum: In vitro effects of artemether combined with haemin depend on cultivation media and appraisal of artemether products appearing in the media

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Schistosoma japonicum: effect of artemether on glutathione S-transferase and superoxide dismutase

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Randomized, double-blind, placebo-controlled trial of oral artemether for the prevention of patent Schistosoma haematobium infections

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Characterization of an omega-class glutathione S-transferase from Schistosoma mansoni with glutaredoxin-like dehydroascorbate reductase and thiol transferase activities

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Molecular and enzymatic characterisation of Schistosoma mansoni thioredoxin

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Enhancement of tolerance to heavy metals and oxidative stress in Dunaliella tertiolecta by Zn-induced phytochelatin synthesis

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Caenorhabditis elegans expresses a functional phytochelatin synthase

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Histopathological changes in juvenile Schistosoma haematobium harboured in hamsters treated with artemether

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Molecular and enzymatic characterization of Schistosoma mansoni thioredoxin peroxidase

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Human placenta thioredoxin reductase. Isolation of the selenoenzyme, steady state kinetics, and inhibition by therapeutic gold compounds

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Tissue expression of the Schistosoma mansoni 28 kDa glutathione S-transferase

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Use of praziquantel in patients with schistosomiasis mansoni previously treated with oxamniquine and/or hycanthone: resistance of Schistosoma mansoni to schistosomicidal agents

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Molecular cloning of a protective antigen of schistosomes

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3638776

Preparation and assay of mammalian thioredoxin and thioredoxin reductase

28 November 2018

1 reference

12 December 2020

Schistosoma japonicumGSHS-TransferaseSj26 Is Not the Molecular Target of Praziquantel Action

1 reference

12 December 2020

Comparative in vitro and in vivo activity of racemic praziquantel and its levorotated isomer on Schistosoma mansoni

1 reference

12 December 2020

Antioxidant systems in Schistosoma mansoni: correlation between susceptibility to oxidant killing and the levels of scavengers of hydrogen peroxide and oxygen free radicals

1 reference

12 December 2020

Effect of artemether against Schistosoma haematobium in experimentally infected hamsters

1 reference

12 December 2020

Aurothioglucose inhibits murine thioredoxin reductase activity in vivo

1 reference

12 December 2020

Comparison of the therapeutic efficacy and side effects of a single dose of levo-praziquantel with mixed isomer praziquantel in 278 cases of schistosomiasis japonica

1 reference

12 December 2020

Hysteresis in thioredoxin-glutathione reductase (TGR) from the adult stage of the liver fluke Fasciola hepatica

1 reference

12 December 2020

Tegumental changes in adult Schistosoma mansoni harbored in mice treated with artemether

1 reference

12 December 2020

Rat liver thioredoxin and thioredoxin reductase: purification and characterization

1 reference

12 December 2020

Function of phytochelatin synthase in catabolism of glutathione-conjugates

1 reference

12 December 2020

Immunization of mice and baboons with the recombinant Sm28GST affects both worm viability and fecundity after experimental infection with Schistosoma mansoni

1 reference

12 December 2020

The Reaction of the Hydroxyl Radical with Glutathione in Neutral and Alkaline Aqueous Solution

1 reference

12 December 2020

Glutathione redox state, lipid peroxide levels, and activities of glutathione enzymes in oltipraz-treated adult Schistosoma mansoni

1 reference

12 December 2020

cDNA cloning and expression analysis of Eisenia fetida (Annelida: Oligochaeta) phytochelatin synthase under cadmium exposure

1 reference

12 December 2020

gamma-Glutamyl transpeptidase activity in Ascaris suum

1 reference

12 December 2020

Hycanthone, a new active metabolite of lucanthone

1 reference

12 December 2020

Cysteine conjugate beta-lyase activity in three species of parasitic helminth

1 reference

12 December 2020

Induction of Schistosoma mansoni glutathione S-transferase by xenobiotics

1 reference

12 December 2020

Structure of the cytosolic Cu,Zn superoxide dismutase fromSchistosoma mansoni

1 reference

12 December 2020

Mode of action of the schistosomicide hycanthone: site of DNA alkylation

1 reference

12 December 2020

The effect of metrifonate in vitro on Schistosoma haematobium and S. mansoni adults

1 reference

12 December 2020

Some negative contrast staining features of a protein from erythrocyte ghosts

1 reference

12 December 2020

The effect of praziquantel treatment on glutathione concentration in Schistosoma mansoni

1 reference

12 December 2020

Factors affecting the inhibition of phosphofructokinase activity of Schistosoma mansoni by trivalent organic antimonials

1 reference

12 December 2020

Biochemical properties of cloned glutathione S-transferases from Schistosoma mansoni and Schistosoma japonicum

1 reference

12 December 2020

Kinetics of egg production and egg excretion by Schistosoma mansoni and S. japonicum in mice infected with a single pair of worms

1 reference

12 December 2020

Schistosoma mansoni: identification and analysis of an mRNA and a gene encoding superoxide dismutase (Cu/Zn)

1 reference

12 December 2020

Schistosomes, liver flukes and Helicobacter pylori. IARC Working Group on the Evaluation of Carcinogenic Risks to Humans. Lyon, 7-14 June 1994

1 reference

12 December 2020

Do antioxidants play a role in schistosome host-parasite interactions?

1 reference

12 December 2020

Purification of three cytosolic glutathione S-transferases from adult Schistosoma mansoni

1 reference

12 December 2020

Hycanthone Resistance: Development in Schistosoma mansoni

1 reference

12 December 2020

Cytosolic peroxiredoxin attenuates the activation of Jnk and p38 but potentiates that of Erk in Hela cells stimulated with tumor necrosis factor-alpha

1 reference

12 December 2020

Mechanisms of inactivation of Schistosoma mansoni and mammalian glutathione S-transferase activity by the antischistosomal drug oltipraz

1 reference

12 December 2020

Crystallization and preliminary X-ray diffraction studies of a protective cloned 28 kDa glutathione S-transferase from Schistosoma mansoni

1 reference

12 December 2020

Identifiers

1 reference

PubMed publication ID

22607149

1 reference