Targeting the indoleamine 2,3-dioxygenase pathway in cancer (Q26775471)

Creative Commons Attribution 4.0 International

volume

3

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issue

1

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page(s)

51

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copyright license

start time

1 December 2015

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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The indoleamine 2,3-dioxygenase pathway controls complement-dependent enhancement of chemo-radiation therapy against murine glioblastoma

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Indoleamine 2,3 dioxygenase and metabolic control of immune responses

28 September 2017

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28 September 2017

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Host indoleamine 2,3-dioxygenase: contribution to systemic acquired tumor tolerance.

28 September 2017

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Tryptophan 2,3-Dioxygenase (TDO) Inhibitors. 3-(2-(Pyridyl)ethenyl)indoles as Potential Anticancer Immunomodulators

28 September 2017

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Dendritic cells, indoleamine 2,3 dioxygenase and acquired immune privilege

28 September 2017

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Hydroxyamidine inhibitors of indoleamine-2,3-dioxygenase potently suppress systemic tryptophan catabolism and the growth of IDO-expressing tumors

28 September 2017

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Targeting indoleamine 2,3-dioxygenase (IDO) to counteract tumour-induced immune dysfunction: from biochemistry to clinical development.

28 September 2017

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Indoleamine 2,3-dioxygenase-expressing mature human monocyte-derived dendritic cells expand potent autologous regulatory T cells.

28 September 2017

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Inhibitors of indoleamine-2,3-dioxygenase for cancer therapy: can we see the wood for the trees?

28 September 2017

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Indoleamine 2,3-dioxygenase controls conversion of Foxp3+ Tregs to TH17-like cells in tumor-draining lymph nodes.

28 September 2017

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28 September 2017

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28 September 2017

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Transcriptional regulation of indoleamine 2,3-dioxygenase (IDO) by tryptophan and its analogue : Down-regulation of the indoleamine 2,3-dioxygenase (IDO) transcription by tryptophan and its analogue.

28 September 2017

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The indoleamine 2,3-dioxygenase pathway is essential for human plasmacytoid dendritic cell-induced adaptive T regulatory cell generation

28 September 2017

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HIV-activated human plasmacytoid DCs induce Tregs through an indoleamine 2,3-dioxygenase-dependent mechanism

28 September 2017

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Indoleamine 2,3-dioxygenase activity of acute myeloid leukemia cells can be measured from patients' sera by HPLC and is inducible by IFN-gamma.

28 September 2017

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IDO1 and IDO2 are expressed in human tumors: levo- but not dextro-1-methyl tryptophan inhibits tryptophan catabolism

28 September 2017

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Indoleamine 2,3-dioxygenase is the anticancer target for a novel series of potent naphthoquinone-based inhibitors.

28 September 2017

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Spontaneous renal allograft acceptance associated with "regulatory" dendritic cells and IDO

28 September 2017

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Levo- but not dextro-1-methyl tryptophan abrogates the IDO activity of human dendritic cells

28 September 2017

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Plasmacytoid dendritic cells from mouse tumor-draining lymph nodes directly activate mature Tregs via indoleamine 2,3-dioxygenase

28 September 2017

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28 September 2017

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Chronic immune activation underlies morbid obesity: is IDO a key player?

28 September 2017

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Indoleamine 2,3-dioxygenase in hematopoietic stem cell transplantation

28 September 2017

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Decreased serum tryptophan concentration predicts poor prognosis in malignant melanoma patients

28 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4678703

Exiguamine A, an indoleamine-2,3-dioxygenase (IDO) inhibitor isolated from the marine sponge Neopetrosia exigua

28 September 2017

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Indoleamine 2,3-dioxygenase is a novel prognostic indicator for endometrial cancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4678703

Prognostic value of indoleamine 2,3-dioxygenase expression in colorectal cancer: effect on tumor-infiltrating T cells.

28 September 2017

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Structure-activity study of brassinin derivatives as indoleamine 2,3-dioxygenase inhibitors.

28 September 2017

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Treatment of autoimmune neuroinflammation with a synthetic tryptophan metabolite

28 September 2017

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Indoleamine 2,3-dioxygenase serves as a marker of poor prognosis in gene expression profiles of serous ovarian cancer cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4678703

Eosinophil granulocytes account for indoleamine 2,3-dioxygenase-mediated immune escape in human non-small cell lung cancer.

28 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4678703

A two-step induction of indoleamine 2,3 dioxygenase (IDO) activity during dendritic-cell maturation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4678703

Recruitment of latent pools of high-avidity CD8(+) T cells to the antitumor immune response

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4678703

Expression of indoleamine 2,3-dioxygenase by plasmacytoid dendritic cells in tumor-draining lymph nodes.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4678703

Tryptophan and the immune response

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4678703

Serum tryptophan decrease correlates with immune activation and impaired quality of life in colorectal cancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4678703

Interferon gamma blocks the growth of Toxoplasma gondii in human fibroblasts by inducing the host cells to degrade tryptophan

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4678703

Induction of indoleamine 2,3-dioxygenase in mouse lung during virus infection

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4678703

Induction of pulmonary indoleamine 2,3-dioxygenase by intraperitoneal injection of bacterial lipopolysaccharide

28 September 2017

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Reprogrammed foxp3(+) regulatory T cells provide essential help to support cross-presentation and CD8(+) T cell priming in naive mice

28 September 2017

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Inhibition of indoleamine 2,3-dioxygenase and tryptophan 2,3-dioxygenase by beta-carboline and indole derivatives

31 May 2018

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Enzyme kinetic and spectroscopic studies of inhibitor and effector interactions with indoleamine 2,3-dioxygenase. 1. Norharman and 4-phenylimidazole binding to the enzyme as inhibitors and heme ligands

31 May 2018

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Extensive profiling of the expression of the indoleamine 2,3-dioxygenase 1 protein in normal and tumoral human tissues

31 May 2018

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CD40Ig treatment results in allograft acceptance mediated by CD8CD45RC T cells, IFN-gamma, and indoleamine 2,3-dioxygenase

21 January 2018

1 reference

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Expression of indoleamine 2,3-dioxygenase (IDO) by endothelial cells: implications for the control of alloresponses

21 January 2018

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Potential regulatory function of human dendritic cells expressing indoleamine 2,3-dioxygenase

21 January 2018

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GCN2 kinase in T cells mediates proliferative arrest and anergy induction in response to indoleamine 2,3-dioxygenase.

21 January 2018

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Indoleamine 2,3-dioxygenase enzyme activity correlates with risk factors for atherosclerosis: the Cardiovascular Risk in Young Finns Study.

21 January 2018

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Cells expressing indoleamine 2,3-dioxygenase inhibit T cell responses.

21 January 2018

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Acute myeloid leukemia cells constitutively express the immunoregulatory enzyme indoleamine 2,3-dioxygenase.

21 January 2018

1 reference

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Tryptophan degradation in patients with gynecological cancer correlates with immune activation

21 January 2018

1 reference

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Inverse correlation between tumoral indoleamine 2,3-dioxygenase expression and tumor-infiltrating lymphocytes in endometrial cancer: its association with disease progression and survival

21 January 2018

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Selective inhibition of IDO1 effectively regulates mediators of antitumor immunity

21 January 2018

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Long-lasting disease stabilization in the absence of toxicity in metastatic lung cancer patients vaccinated with an epitope derived from indoleamine 2,3 dioxygenase

21 January 2018

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Induction of antigen-specific immunity with a vaccine targeting NY-ESO-1 to the dendritic cell receptor DEC-205.

21 January 2018

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A key in vivo antitumor mechanism of action of natural product-based brassinins is inhibition of indoleamine 2,3-dioxygenase

21 January 2018

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Increased synthesis of indoleamine-2,3-dioxygenase protein is positively associated with impaired survival in patients with serous-type, but not with other types of, ovarian cancer

21 January 2018

1 reference

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Indoleamine 2,3-dioxygenase, Tregs and Cancer

28 November 2018

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12 December 2020

Dendritic cells have the option to express IDO-mediated suppression or not

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12 December 2020

Indoleamine 2, 3-dioxygenase expression in cells of human acute monocyte leukemia (M(5)) and acute lymphocyte leukemia and therapeutic effect of its inhibitor 1-methyl tryptophan

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12 December 2020

Indoleamine 2,3-dioxygenase production by human dendritic cells results in the inhibition of T cell proliferation

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12 December 2020

Tryptophan catabolism generates autoimmune-preventive regulatory T cells

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12 December 2020

Manipulation of indoleamine 2,3-dioxygenase (IDO) for clinical transplantation: promises and challenges

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12 December 2020

Crucial role of interferon-gamma and stimulated macrophages in cardiovascular disease

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12 December 2020

Inhibitors of human indoleamine 2,3-dioxygenase identified with a target-based screen in yeast

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12 December 2020

10.1186/S40425-015-0094-9

Identifiers

DOI

1 reference

Dimensions Publication ID

1 reference

9 September 2019

https://scigraph.springernature.com/pub.10.1186/s40425-015-0094-9

1 reference

1 reference

PubMed publication ID

26674411

1 reference