Epigenetic silencing of tumor suppressor genes: Paradigms, puzzles, and potential (Q26753019)

2

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Khalid Hilmi

3

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Maud Marques

4

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Michael Witcher

Biochimica et Biophysica Acta

5

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language of work or name

English

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publication date

April 2016

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published in

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volume

1865

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issue

2

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page(s)

275-88

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cites work

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Abrogated response to cellular stress identifies DCIS associated with subsequent tumor events and defines basal-like breast tumors

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Transient low doses of DNA-demethylating agents exert durable antitumor effects on hematological and epithelial tumor cells

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Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs

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DNA sequence-dependent compartmentalization and silencing of chromatin at the nuclear lamina

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DNA methylation of transcriptional enhancers and cancer predisposition

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Poly(ADP-ribosyl)ation regulates insulator function and intrachromosomal interactions in Drosophila

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Disruptions of topological chromatin domains cause pathogenic rewiring of gene-enhancer interactions

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Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses

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DNA-Demethylating Agents Target Colorectal Cancer Cells by Inducing Viral Mimicry by Endogenous Transcripts.

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CTCF-Mediated Human 3D Genome Architecture Reveals Chromatin Topology for Transcription.

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7 January 2021

Linking DNA methyltransferases to epigenetic marks and nucleosome structure genome-wide in human tumor cells

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7 January 2021

Role of DNA Methylation in Modulating Transcription Factor Occupancy

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7 January 2021

Treatment of Higher-Risk Myelodysplastic Syndromes After Failure of Hypomethylating Agents

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Clinicopathologic significance of DNA methyltransferase 1, 3a, and 3b overexpression in Tunisian breast cancers.

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Recruitment of P-TEFb for stimulation of transcriptional elongation by the bromodomain protein Brd4

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7 January 2021

A transient heterochromatic state in Xist preempts X inactivation choice without RNA stabilization

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7 January 2021

Epigenetic silencing of the p16(INK4a) tumor suppressor is associated with loss of CTCF binding and a chromatin boundary

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Epigenetic silencing of the RASSF1A tumor suppressor gene through HOXB3-mediated induction of DNMT3B expression

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Molecular interplay of the noncoding RNA ANRIL and methylated histone H3 lysine 27 by polycomb CBX7 in transcriptional silencing of INK4a

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7 January 2021

Molecular Mechanisms of Long Noncoding RNAs

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7 January 2021

Gene silencing triggers polycomb repressive complex 2 recruitment to CpG islands genome wide

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7 January 2021

CTCF Binding Polarity Determines Chromatin Looping.

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7 January 2021

Direct ChIP-bisulfite sequencing reveals a role of H3K27me3 mediating aberrant hypermethylation of promoter CpG islands in cancer cells

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7 January 2021

Conserved Histone Variant H2A.Z Protects Euchromatin from the Ectopic Spread of Silent Heterochromatin

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7 January 2021

E-cadherin expression is silenced by DNA methylation in cervical cancer cell lines and tumours.

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Targeting DNA methylation with small molecules: what's next?

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DNA hypomethylation leads to elevated mutation rates

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A gene complex controlling segmentation in Drosophila

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7 January 2021

Hypomethylation distinguishes genes of some human cancers from their normal counterparts

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7 January 2021

Sp1 elements protect a CpG island from de novo methylation

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7 January 2021

DNMT1 and DNMT3b cooperate to silence genes in human cancer cells

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7 January 2021

Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer

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7 January 2021

Vorinostat-induced autophagy switches from a death-promoting to a cytoprotective signal to drive acquired resistance

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7 January 2021

Histone deacetylase inhibitors induce apoptosis in myeloid leukemia by suppressing autophagy

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7 January 2021

Repression of the human dihydrofolate reductase gene by a non-coding interfering transcript

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7 January 2021

Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project

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7 January 2021

Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions

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https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

Histone H2A.Z and DNA methylation are mutually antagonistic chromatin marks

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https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

Cooperative binding of two acetylation marks on a histone tail by a single bromodomain

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7 January 2021

Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis

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7 January 2021

A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression

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7 January 2021

DNA-binding factors shape the mouse methylome at distal regulatory regions

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https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

Topological domains in mammalian genomes identified by analysis of chromatin interactions

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7 January 2021

EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations

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7 January 2021

Competition between DNA methylation and transcription factors determines binding of NRF1.

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7 January 2021

Insulator dysfunction and oncogene activation in IDH mutant gliomas

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7 January 2021

Acetylation site specificities of lysine deacetylase inhibitors in human cells

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7 January 2021

Histone acetylation by Trrap-Tip60 modulates loading of repair proteins and repair of DNA double-strand breaks

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7 January 2021

A selective inhibitor of EZH2 blocks H3K27 methylation and kills mutant lymphoma cells

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7 January 2021

DNA methylation of oestrogen-regulated enhancers defines endocrine sensitivity in breast cancer.

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7 January 2021

Sir2p and Sas2p opposingly regulate acetylation of yeast histone H4 lysine16 and spreading of heterochromatin

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7 January 2021

Combinatorial patterns of histone acetylations and methylations in the human genome

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7 January 2021

Gene silencing in cancer by histone H3 lysine 27 trimethylation independent of promoter DNA methylation

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7 January 2021

Genome-wide analysis of Arabidopsis thaliana DNA methylation uncovers an interdependence between methylation and transcription.

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7 January 2021

Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer

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7 January 2021

CTCF/cohesin-binding sites are frequently mutated in cancer

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7 January 2021

Genome-wide association study identifies five susceptibility loci for glioma

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7 January 2021

Genome-wide association study identifies five new breast cancer susceptibility loci

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7 January 2021

CTCF-mediated functional chromatin interactome in pluripotent cells

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7 January 2021

Increased methylation variation in epigenetic domains across cancer types

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7 January 2021

Identification of genetic elements that autonomously determine DNA methylation states

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7 January 2021

Regions of focal DNA hypermethylation and long-range hypomethylation in colorectal cancer coincide with nuclear lamina-associated domains

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7 January 2021

Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma

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7 January 2021

SWI/SNF-mutant cancers depend on catalytic and non-catalytic activity of EZH2

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7 January 2021

A decade of exploring the cancer epigenome — biological and translational implications

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7 January 2021

Targeting bromodomains: epigenetic readers of lysine acetylation

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7 January 2021

Protein acetylation in metabolism - metabolites and cofactors

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7 January 2021

CTCF: an architectural protein bridging genome topology and function

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7 January 2021

The growing landscape of lysine acetylation links metabolism and cell signalling

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7 January 2021

Structure and function of long noncoding RNAs in epigenetic regulation

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7 January 2021

Transcriptional regulation by Polycomb group proteins

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7 January 2021

PRC2 binds active promoters and contacts nascent RNAs in embryonic stem cells.

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7 January 2021

Epigenetic regulation of the human p53 gene promoter by the CTCF transcription factor in transformed cell lines.

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7 January 2021

Long non-coding RNA ANRIL is required for the PRC2 recruitment to and silencing of p15INK4B tumor suppressor gene

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7 January 2021

Carcinogen-specific mutational and epigenetic alterations in INK4A, INK4B and p53 tumour-suppressor genes drive induced senescence bypass in normal diploid mammalian cells.

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7 January 2021

The NuRD complex cooperates with DNMTs to maintain silencing of key colorectal tumor suppressor genes

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7 January 2021

Global identification of genes targeted by DNMT3b for epigenetic silencing in lung cancer.

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7 January 2021

Silencing of transgene transcription precedes methylation of promoter DNA and histone H3 lysine 9.

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7 January 2021

Expression levels of DNA methyltransferase genes do not correlate with p15INK4B gene methylation in myelodysplastic syndromes.

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7 January 2021

The expression of DNA methyltransferases and methyl-CpG-binding proteins is not associated with the methylation status of p14(ARF), p16(INK4a) and RASSF1A in human lung cancer cell lines

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7 January 2021

Resetting the histone code at CDKN2A in HNSCC by inhibition of DNA methylation

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https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

Modulation of DNMT1 activity by ADP-ribose polymers

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https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

Site-specific DNA methylation by a complex of PU.1 and Dnmt3a/b

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https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

ADP-ribose polymers localized on Ctcf-Parp1-Dnmt1 complex prevent methylation of Ctcf target sites

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7 January 2021

Frequent switching of Polycomb repressive marks and DNA hypermethylation in the PC3 prostate cancer cell line

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7 January 2021

Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression

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7 January 2021

Selective association of the methyl-CpG binding protein MBD2 with the silent p14/p16 locus in human neoplasia

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7 January 2021

Deletion of the de novo DNA methyltransferase Dnmt3a promotes lung tumor progression

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7 January 2021

Selective inhibition of Ezh2 by a small molecule inhibitor blocks tumor cells proliferation

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https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

Genome-wide targeting of the epigenetic regulatory protein CTCF to gene promoters by the transcription factor TFII-I.

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https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells

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7 January 2021

ACETYLATION AND METHYLATION OF HISTONES AND THEIR POSSIBLE ROLE IN THE REGULATION OF RNA SYNTHESIS

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7 January 2021

Inhibition of DNA methyltransferase stimulates the expression of signal transducer and activator of transcription 1, 2, and 3 genes in colon tumor cells

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https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

Polycomb repressive complex 1 (PRC1) disassembles RNA polymerase II preinitiation complexes.

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https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

CCCTC-binding factor activates PARP-1 affecting DNA methylation machinery.

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https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

The acetylation of alpha-tubulin and its relationship to the assembly and disassembly of microtubules

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https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

The role of EZH2 and DNA methylation in the silencing of the tumour suppressor RUNX3 in colorectal cancer

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https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer

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https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

CTCF binding sites promote transcription initiation and prevent DNA methylation on the maternal allele at the imprinted H19/Igf2 locus

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https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

Aberrant de novo methylation of the p16INK4A CpG island is initiated post gene silencing in association with chromatin remodelling and mimics nucleosome positioning

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https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

Patterns of CTCF and ZFHX3 Mutation and Associated Outcomes in Endometrial Cancer

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7 January 2021

Preclinical Investigation of the Novel Histone Deacetylase Inhibitor AR-42 in the Treatment of Cancer-Induced Cachexia

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7 January 2021

The human DNA methyltransferases (DNMTs) 1, 3a and 3b: coordinate mRNA expression in normal tissues and overexpression in tumors

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7 January 2021

CTCF induces histone variant incorporation, erases the H3K27me3 histone mark and opens chromatin

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https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

DNA hypermethylation profiles associated with glioma subtypes and EZH2 and IGFBP2 mRNA expression.

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7 January 2021

Recent advances in primary cutaneous T-cell lymphoma

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7 January 2021

Suberoylanilide hydroxamic acid induces limited changes in the transcriptome of primary CD4(+) T cells.

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7 January 2021

Dnmt3b promotes tumorigenesis in vivo by gene-specific de novo methylation and transcriptional silencing

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7 January 2021

Regulating RNA polymerase pausing and transcription elongation in embryonic stem cells

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https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

CTCF regulates the human p53 gene through direct interaction with its natural antisense transcript, Wrap53.

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7 January 2021

CTCF mediates long-range chromatin looping and local histone modification in the beta-globin locus

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7 January 2021

The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells

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7 January 2021

Sp1 sites in the mouse aprt gene promoter are required to prevent methylation of the CpG island

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7 January 2021

Functional selectivity of recombinant mammalian SWI/SNF subunits

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7 January 2021

Global analysis of the insulator binding protein CTCF in chromatin barrier regions reveals demarcation of active and repressive domains

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https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

Genome-scale analysis of aberrant DNA methylation in colorectal cancer

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7 January 2021

Global DNA hypomethylation coupled to repressive chromatin domain formation and gene silencing in breast cancer

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7 January 2021

Widespread plasticity in CTCF occupancy linked to DNA methylation

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7 January 2021

Drosophila CTCF tandemly aligns with other insulator proteins at the borders of H3K27me3 domains

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7 January 2021

Oncometabolites: tailoring our genes

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https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

Histone Deacetylase Inhibitors Stimulate Histone H3 Lysine 4 Methylation in Part Via Transcriptional Repression of Histone H3 Lysine 4 Demethylases

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

Role of histone H3 lysine 27 methylation in Polycomb-group silencing

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

Chromosomal Instability and Tumors Promoted by DNA Hypomethylation

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

Induction of Tumors in Mice by Genomic Hypomethylation

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

Antisense transcription in the mammalian transcriptome

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

Polycomb proteins targeted by a short repeat RNA to the mouse X chromosome

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

The Air noncoding RNA epigenetically silences transcription by targeting G9a to chromatin

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

Genome-wide evolutionary analysis of eukaryotic DNA methylation.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

Long noncoding RNA as modular scaffold of histone modification complexes

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

CTCF establishes discrete functional chromatin domains at the Hox clusters during differentiation

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

Dynamics of epigenetic regulation at the single-cell level

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

Genomic DNA hypomethylation by histone deacetylase inhibition implicates DNMT1 nuclear dynamics

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

CTCF interacts with and recruits the largest subunit of RNA polymerase II to CTCF target sites genome-wide

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

An exceptionally conserved transcriptional repressor, CTCF, employs different combinations of zinc fingers to bind diverged promoter sequences of avian and mammalian c-myc oncogenes

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

Chromatin inactivation precedes de novo DNA methylation during the progressive epigenetic silencing of the RASSF1A promoter

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

Sequential DNA methylation changes are associated with DNMT3B overexpression in colorectal neoplastic progression

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

CTCF function is modulated by neighboring DNA binding factors

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

The tale of protein lysine acetylation in the cytoplasm.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

Histone deacetylase inhibitors decrease DNA methyltransferase-3B messenger RNA stability and down-regulate de novo DNA methyltransferase activity in human endometrial cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

Silenced tumor suppressor genes reactivated by DNA demethylation do not return to a fully euchromatic chromatin state

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

Functional diversity of DNA methyltransferase inhibitors in human cancer cell lines.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

Identification of EZH2 as a molecular marker for a precancerous state in morphologically normal breast tissues

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

Epigenetic regulation of the human retinoblastoma tumor suppressor gene promoter by CTCF

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

DNA methylation and complete transcriptional silencing of cancer genes persist after depletion of EZH2.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

Expression of Delta DNMT3B variants and its association with promoter methylation of p16 and RASSF1A in primary non-small cell lung cancer.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

Changes in DNA Methylation Patterns in Subjects Exposed to Low-Dose Benzene

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

Delta DNMT3B variants regulate DNA methylation in a promoter-specific manner.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

Polycomb CBX7 promotes initiation of heritable repression of genes frequently silenced with cancer-specific DNA hypermethylation

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

Upregulation of miR-196a and HOTAIR Drive Malignant Character in Gastrointestinal Stromal Tumors

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

DNA methylation does not stably lock gene expression but instead serves as a molecular mark for gene silencing memory

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

A recombinant reporter system for monitoring reactivation of an endogenously DNA hypermethylated gene.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

Mapping Geographic Zones of Cancer Risk with Epigenetic Biomarkers in Normal Breast Tissue

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

Histone deacetylase inhibitor panobinostat induces clinical responses with associated alterations in gene expression profiles in cutaneous T-cell lymphoma

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

CpG island methylator phenotype predicts progression of malignant melanoma

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

Decreased poly(ADP-ribosyl)ation of CTCF, a transcription factor, is associated with breast cancer phenotype and cell proliferation

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

Superior efficacy of a combined epigenetic therapy against human mantle cell lymphoma cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

EZH2 protein expression associates with the early pathogenesis, tumor progression, and prognosis of non-small cell lung carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

miR-200b and miR-200c as prognostic factors and mediators of gastric cancer cell progression.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

Epigenetics in cancer: targeting chromatin modifications

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

Genes methylated by DNA methyltransferase 3b are similar in mouse intestine and human colon cancer

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

Signatures of polycomb repression and reduced H3K4 trimethylation are associated with p15INK4b DNA methylation in AML.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

EZH2-mediated epigenetic silencing in germinal center B cells contributes to proliferation and lymphomagenesis

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

HDAC inhibitors and decitabine are highly synergistic and associated with unique gene-expression and epigenetic profiles in models of DLBCL

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

Recent developments in myelodysplastic syndromes.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

Expression of DNA methyltransferases DNMT1, 3A, and 3B in normal hematopoiesis and in acute and chronic myelogenous leukemia

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

Gain of DNA methylation is enhanced in the absence of CTCF at the human retinoblastoma gene promoter

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

CTCF regulates the local epigenetic state of ribosomal DNA repeats

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

DNA methylation of distal regulatory sites characterizes dysregulation of cancer genes

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

Increased expression of the long non-coding RNA ANRIL promotes lung cancer cell metastasis and correlates with poor prognosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

P16-specific DNA methylation by engineered zinc finger methyltransferase inactivates gene transcription and promotes cancer metastasis

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

Cells adapt to the epigenomic disruption caused by histone deacetylase inhibitors through a coordinated, chromatin-mediated transcriptional response

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

Colorectal cancer with mutation in BRAF, KRAS, and wild-type with respect to both oncogenes showing different patterns of DNA methylation

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

EZH2 expression is associated with high proliferation rate and aggressive tumor subgroups in cutaneous melanoma and cancers of the endometrium, prostate, and breast

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

Maternally expressed gene 3 (MEG3) noncoding ribonucleic acid: isoform structure, expression, and functions

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

Maternal depletion of CTCF reveals multiple functions during oocyte and preimplantation embryo development

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

The recruitment of chromatin modifiers by long noncoding RNAs: lessons from PRC2.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

The insulator binding protein CTCF positions 20 nucleosomes around its binding sites across the human genome

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

Hypomethylation of a LINE-1 promoter activates an alternate transcript of the MET oncogene in bladders with cancer

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

The intronic long noncoding RNA ANRASSF1 recruits PRC2 to the RASSF1A promoter, reducing the expression of RASSF1A and increasing cell proliferation.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

Transcription factor occupancy can mediate active turnover of DNA methylation at regulatory regions.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

High DNA methyltransferase DNMT3B levels: a poor prognostic marker in acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

DNA methyltransferase inhibitors in cancer: a chemical and therapeutic patent overview and selected clinical studies

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

The transcription factor nerve growth factor-inducible protein a mediates epigenetic programming: altering epigenetic marks by immediate-early genes.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

Management of treatment-related toxicity in advanced ovarian cancer

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

Alterations of immune response of Non-Small Cell Lung Cancer with Azacytidine

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

Long noncoding RNA ANRIL indicates a poor prognosis of gastric cancer and promotes tumor growth by epigenetically silencing of miR-99a/miR-449a

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

Induction of a specific CD8+ T-cell response to cancer/testis antigens by demethylating pre-treatment against osteosarcoma

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

Long non-coding RNA HOTAIR promotes glioblastoma cell cycle progression in an EZH2 dependent manner

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

In vivo treatment with epigenetic modulating agents induces transcriptional alterations associated with prognosis and immunomodulation in multiple myeloma.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

DNA methyltransferases messenger RNA expression and aberrant methylation of CpG islands in non-small-cell lung cancer: association and prognostic value

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

DNA methylation-induced E-cadherin silencing is correlated with the clinicopathological features of melanoma

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

Expression changes in EZH2, but not in BMI-1, SIRT1, DNMT1 or DNMT3B are associated with DNA methylation changes in prostate cancer

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

Synergistic chromatin repression of the tumor suppressor gene RARB in human prostate cancers

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

Whole genome DNA methylation signature of HER2-positive breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

Targeting of EZH2 to a defined genomic site is sufficient for recruitment of Dnmt3a but not de novo DNA methylation.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

Dnmt3/transcription factor interactions as crucial players in targeted DNA methylation.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

The hallmarks of cancer: a long non-coding RNA point of view.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2016.04.001

7 January 2021

10.1016/J.BBCAN.2016.04.001

Identifiers

DOI

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

PubMed publication ID

27085853

1 reference

Consolidated OpenCitations Corpus – April 2017