Focal glial activation coincides with increased BACE1 activation and precedes amyloid plaque deposition in APP[V717I] transgenic mice (Q24812365)

5 July 2017

title

Focal glial activation coincides with increased BACE1 activation and precedes amyloid plaque deposition in APP[V717I] transgenic mice (English)

1 reference

5 July 2017

4

Ilse Dewachter

1 reference

5 July 2017

7

Fred Van Leuven

1 reference

5 July 2017

6

Thomas Klockgether

1 reference

5 July 2017

Michael T Heneka

1

1 reference

5 July 2017

Magdalena Sastre

series ordinal

2

1 reference

5 July 2017

Lucia Dumitrescu-Ozimek

series ordinal

3

1 reference

5 July 2017

Jochen Walter

series ordinal

5

1 reference

5 July 2017

language of work or name

English

0 references

publication date

7 October 2005

1 reference

Journal of Neuroinflammation

5 July 2017

published in

1 reference

5 July 2017

volume

2

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5 July 2017

issue

1

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page(s)

22

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Inflammation and Alzheimer's disease

5 July 2017

cites work

1 reference

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Early phenotypic changes in transgenic mice that overexpress different mutants of amyloid precursor protein in brain

7 April 2017

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Spotlight on BACE: the secretases as targets for treatment in Alzheimer disease

7 April 2017

1 reference

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beta-site APP cleaving enzyme mRNA expression in APP transgenic mice: anatomical overlap with transgene expression and static levels with aging

7 April 2017

1 reference

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Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

7 April 2017

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Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse

7 April 2017

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Amyloid deposition as the central event in the aetiology of Alzheimer's disease

7 April 2017

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Neuroinflammatory perspectives on the two faces of Alzheimer's disease

7 April 2017

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Nonsteroidal anti-inflammatory drugs and peroxisome proliferator-activated receptor-gamma agonists modulate immunostimulated processing of amyloid precursor protein through regulation of beta-secretase.

28 September 2017

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Identification of a beta-secretase activity, which truncates amyloid beta-peptide after its presenilin-dependent generation

28 September 2017

1 reference

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A portrait of Alzheimer secretases--new features and familiar faces

28 September 2017

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Neuronal and glial beta-secretase (BACE) protein expression in transgenic Tg2576 mice with amyloid plaque pathology

28 September 2017

1 reference

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Amyloid-beta peptide fragments p3 and p4 induce pro-inflammatory cytokine and chemokine production in vitro and in vivo.

28 September 2017

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Beta-amyloid-induced glial expression of both pro- and anti-inflammatory cytokines in cerebral cortex of aged transgenic Tg2576 mice with Alzheimer plaque pathology

28 September 2017

1 reference

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Prominent cerebral amyloid angiopathy in transgenic mice overexpressing the london mutant of human APP in neurons.

28 September 2017

1 reference

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Association of interleukin-1 gene polymorphisms with Alzheimer's disease

28 September 2017

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Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology

28 September 2017

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Microglial activation by Alzheimer amyloid precursor protein and modulation by apolipoprotein E.

28 September 2017

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Inducible nitric oxide synthase in tangle-bearing neurons of patients with Alzheimer's disease

28 September 2017

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Arthritis and anti-inflammatory agents as possible protective factors for Alzheimer's disease: a review of 17 epidemiologic studies

28 September 2017

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Association between polymorphism in regulatory region of gene encoding tumour necrosis factor alpha and risk of Alzheimer's disease and vascular dementia: a case-control study

28 September 2017

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Expression of beta-secretase mRNA in transgenic Tg2576 mouse brain with Alzheimer plaque pathology

30 May 2018

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Ibuprofen suppresses plaque pathology and inflammation in a mouse model for Alzheimer's disease.

30 May 2018

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Evidence that increased hippocampal expression of the cytokine interleukin-1 beta is a common trigger for age- and stress-induced impairments in long-term potentiation.

30 May 2018

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Reactive microglia in patients with senile dementia of the Alzheimer type are positive for the histocompatibility glycoprotein HLA-DR.

30 May 2018

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Up-regulation of the inflammatory cytokines IFN-gamma and IL-12 and down-regulation of IL-4 in cerebral cortex regions of APP(SWE) transgenic mice

30 May 2018

1 reference

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Nonsteroidal Antiinflammatory Drugs and the Risk of Alzheimer's Disease

28 November 2018

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Amyloid production and deposition in mutant amyloid precursor protein and presenilin-1 yeast artificial chromosome transgenic mice.

28 November 2018

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A genetic variation of the inflammatory cytokine interleukin-6 delays the initial onset and reduces the risk for sporadic Alzheimer's disease.

28 November 2018

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Widespread peroxynitrite-mediated damage in Alzheimer's disease

28 November 2018

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Clinical trial of indomethacin in Alzheimer's disease.

28 November 2018

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Endogenous brain cytokine mRNA and inflammatory responses to lipopolysaccharide are elevated in the Tg2576 transgenic mouse model of Alzheimer's disease

28 November 2018

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12 December 2020

Identification of canine glial cells by nonradioactive in situ hybridization

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12 December 2020

TNFalpha plus IFNgamma induce the production of Alzheimer beta-amyloid peptides and decrease the secretion of APPs

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12 December 2020

Evidence for glial-mediated inflammation in aged APP(SW) transgenic mice

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12 December 2020

Induction of cytokines in glial cells surrounding cortical beta-amyloid plaques in transgenic Tg2576 mice with Alzheimer pathology

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12 December 2020

The inhibitory effects of interleukin-6 on synaptic plasticity in the rat hippocampus are associated with an inhibition of mitogen-activated protein kinase ERK

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12 December 2020

Identifiers

DOI

10.1186/1742-2094-2-22

1 reference

Dimensions Publication ID

5 July 2017

1 reference

https://scigraph.springernature.com/pub.10.1186/1742-2094-2-22

OpenCitations bibliographic resource ID

9 September 2019

1743172

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

5 July 2017

1 reference