FGF10/FGFR2b signaling plays essential roles during in vivo embryonic submandibular salivary gland morphogenesis (Q24811853)

Fibroblast growth factor receptor 2

GOA release 2020-03-11

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GOA release 2020-03-11

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5

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author name string

Tina Jaskoll

1

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George Abichaker

2

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Daniel Witcher

3

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Frederic G Sala

4

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Mohammad K Hajihosseini

6

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Michael Melnick

BMC Developmental Biology

7

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language of work or name

English

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publication date

2005

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published in

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volume

5

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issue

1

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page(s)

11

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cites work

The functional genomic response of developing embryonic submandibular glands to NF-kappa B inhibition

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Fibroblast growth factors

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Fgf10 expression identifies parabronchial smooth muscle cell progenitors and is required for their entry into the smooth muscle cell lineage

7 April 2017

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Mutations in the gene encoding fibroblast growth factor 10 are associated with aplasia of lacrimal and salivary glands

7 April 2017

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Promotion and attenuation of FGF signaling through the Ras-MAPK pathway

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FGF8 dose-dependent regulation of embryonic submandibular salivary gland morphogenesis

7 April 2017

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Sonic hedgehog signaling plays an essential role during embryonic salivary gland epithelial branching morphogenesis

7 April 2017

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Inferring genetic networks and identifying compound mode of action via expression profiling

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A genomic regulatory network for development

7 April 2017

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Role of FGF10/FGFR2b signaling during mammary gland development in the mouse embryo

7 April 2017

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FGF10 acts as a major ligand for FGF receptor 2 IIIb in mouse multi-organ development

7 April 2017

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Endogenous and ectopic gland induction by FGF-10

7 April 2017

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Fgf10 is essential for limb and lung formation

7 April 2017

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Gene expression profiles of mouse submandibular gland development: FGFR1 regulates branching morphogenesis in vitro through BMP- and FGF-dependent mechanisms

7 April 2017

1 reference

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Embryonic submandibular gland morphogenesis: stage-specific protein localization of FGFs, BMPs, Pax6 and Pax9 in normal mice and abnormal SMG phenotypes in FgfR2-IIIc(+/Delta), BMP7(-/-) and Pax6(-/-) mice

7 April 2017

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Submandibular gland morphogenesis: stage-specific expression of TGF-alpha/EGF, IGF, TGF-beta, TNF, and IL-6 signal transduction in normal embryonic mice and the phenotypic effects of TGF-beta2, TGF-beta3, and EGF-r null mutations

7 April 2017

1 reference

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Fgf-10 is required for both limb and lung development and exhibits striking functional similarity to Drosophila branchless

7 April 2017

1 reference

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Biochemical analysis of pathogenic ligand-dependent FGFR2 mutations suggests distinct pathophysiological mechanisms for craniofacial and limb abnormalities

7 April 2017

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Role of PI 3-kinase and PIP3 in submandibular gland branching morphogenesis

28 September 2017

1 reference

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Regulatory gene networks and the properties of the developmental process

28 September 2017

1 reference

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Mouse submandibular gland morphogenesis: a paradigm for embryonic signal processing

28 September 2017

1 reference

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Signaling by fibroblast growth factors: the inside story

28 September 2017

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A splicing switch and gain-of-function mutation in FgfR2-IIIc hemizygotes causes Apert/Pfeiffer-syndrome-like phenotypes

28 September 2017

1 reference

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Fibroblast growth factor receptor 2-IIIb acts upstream of Shh and Fgf4 and is required for limb bud maintenance but not for the induction of Fgf8, Fgf10, Msx1, or Bmp4.

28 September 2017

1 reference

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Soluble dominant-negative receptor uncovers essential roles for fibroblast growth factors in multi-organ induction and patterning

28 September 2017

1 reference

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An important role for the IIIb isoform of fibroblast growth factor receptor 2 (FGFR2) in mesenchymal-epithelial signalling during mouse organogenesis.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1184065

Epidermal growth factor system is a physiological regulator of development of the mouse fetal submandibular gland and regulates expression of the alpha6-integrin subunit

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1184065

FGFR2b signaling regulates ex vivo submandibular gland epithelial cell proliferation and branching morphogenesis

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1184065

Common and distinct elements in cellular signaling via EGF and FGF receptors

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1184065

Fgf10 maintains notch activation, stimulates proliferation, and blocks differentiation of pancreatic epithelial cells

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1184065

The IIIb isoform of fibroblast growth factor receptor 2 is required for proper growth and branching of pancreatic ductal epithelium but not for differentiation of exocrine or endocrine cells.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1184065

Maternally expressed PGK-Cre transgene as a tool for early and uniform activation of the Cre site-specific recombinase

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1184065

The ERK-1/2 signaling pathway is involved in the stimulation of branching morphogenesis of fetal mouse submandibular glands by EGF

28 November 2018

1 reference

12 December 2020

Fgf10 is essential for maintaining the proliferative capacity of epithelial progenitor cells during early pancreatic organogenesis

1 reference

12 December 2020

EGF-stimulated signaling by means of PI3K, PLCgamma1, and PKC isozymes regulates branching morphogenesis of the fetal mouse submandibular gland

1 reference

12 December 2020

Cell proliferation is not required for the initiation of early cleft formation in mouse embryonic submandibular epithelium in vitro

1 reference

12 December 2020

Identifiers

DOI

10.1186/1471-213X-5-11

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Dimensions Publication ID

1052568319

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1 reference

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PubMed publication ID

15972105

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