At the crossroads of SUMO and NF-kappaB (Q24798022)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14613580%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

title

At the crossroads of SUMO and NF-kappaB (English)

1 reference

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21 December 2019

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2

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21 December 2019

author name string

Martin P Kracklauer

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14613580%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

language of work or name

English

0 references

publication date

5 November 2003

1 reference

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21 December 2019

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21 December 2019

volume

2

1 reference

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21 December 2019

issue

1

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page(s)

39

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Enzymes of the SUMO modification pathway localize to filaments of the nuclear pore complex.

21 December 2019

cites work

1 reference

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The p65 (RelA) subunit of NF-kappaB interacts with the histone deacetylase (HDAC) corepressors HDAC1 and HDAC2 to negatively regulate gene expression

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=280695

Control of NF-kappa B transcriptional activation by signal induced proteolysis of I kappa B alpha

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=280695

SUMO-1 modification activates the transcriptional response of p53

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=280695

IkappaB kinases phosphorylate NF-kappaB p65 subunit on serine 536 in the transactivation domain

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=280695

Structure of an IkappaBalpha/NF-kappaB complex

7 April 2017

1 reference

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A cytokine-responsive IκB kinase that activates the transcription factor NF-κB

7 April 2017

1 reference

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I kappa B epsilon, a novel member of the I kappa B family, controls RelA and cRel NF-kappa B activity

7 April 2017

1 reference

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The NF-kappa B and I kappa B proteins: new discoveries and insights

7 April 2017

1 reference

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NF-kappa B controls expression of inhibitor I kappa B alpha: evidence for an inducible autoregulatory pathway

7 April 2017

1 reference

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Multiple nuclear factors interact with the immunoglobulin enhancer sequences

7 April 2017

1 reference

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Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity

7 April 2017

1 reference

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NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses

7 April 2017

2 references

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Unconventional tethering of Ulp1 to the transport channel of the nuclear pore complex by karyopherins

7 April 2017

1 reference

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Acetylation of RelA at discrete sites regulates distinct nuclear functions of NF-kappaB.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=280695

Tumor necrosis factor alpha-induced phosphorylation of RelA/p65 on Ser529 is controlled by casein kinase II

7 April 2017

1 reference

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Silencing mediator of retinoic acid and thyroid hormone receptors, as a novel transcriptional corepressor molecule of activating protein-1, nuclear factor-kappaB, and serum response factor

7 April 2017

1 reference

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Functional heterogeneity of small ubiquitin-related protein modifiers SUMO-1 versus SUMO-2/3

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=280695

The ubiquitin-homology protein, DAP-1, associates with tumor necrosis factor receptor (p60) death domain and induces apoptosis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=280695

SUMO-1 modification of IkappaBalpha inhibits NF-kappaB activation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=280695

Direct phosphorylation of IkappaB by IKKalpha and IKKbeta: discrimination between free and NF-kappaB-bound substrate

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=280695

hUBC9 associates with MEKK1 and type I TNF-alpha receptor and stimulates NFkappaB activity

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=280695

The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=280695

Identification and characterization of an IkappaB kinase

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=280695

Site-specific phosphorylation of IkappaBalpha by a novel ubiquitination-dependent protein kinase activity

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=280695

SUMO-1 modification represses Sp3 transcriptional activation and modulates its subnuclear localization

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=280695

Phosphorylation of NF-kappa B p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=280695

Missing pieces in the NF-kappaB puzzle

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=280695

Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases

7 April 2017

1 reference

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The IkappaB-NF-kappaB signaling module: temporal control and selective gene activation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=280695

SUMO-1 conjugation in vivo requires both a consensus modification motif and nuclear targeting

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=280695

SUMO--nonclassical ubiquitin

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=280695

Structure, regulation and function of NF-kappa B

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=280695

Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=280695

Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=280695

Inducibility of kappa immunoglobulin enhancer-binding protein Nf-kappa B by a posttranslational mechanism

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=280695

NF-kappa B: a pleiotropic mediator of inducible and tissue-specific gene control

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=280695

Evolution and function of ubiquitin-like protein-conjugation systems

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=280695

Post-translational modification by the small ubiquitin-related modifier SUMO has big effects on transcription factor activity

9 May 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=280695

Small ubiquitin-like modifier conjugation regulates nuclear export of TEL, a putative tumor suppressor

28 September 2017

1 reference

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Regulating the regulators: lysine modifications make their mark

28 September 2017

1 reference

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28 September 2017

1 reference

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Synthesis and turn-over of the replicative Cdc6 protein during the HeLa cell cycle

28 September 2017

1 reference

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Conjugation of Smt3 to dorsal may potentiate the Drosophila immune response

28 September 2017

1 reference

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Fluorescence resonance energy transfer microscopy of localized protein interactions in the living cell nucleus

28 September 2017

1 reference

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Novel strategies for immortalization of human hepatocytes

28 September 2017

1 reference

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Coupled transcription and translation within nuclei of mammalian cells.

28 September 2017

1 reference

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Postrepression activation of NF-kappaB requires the amino-terminal nuclear export signal specific to IkappaBalpha

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=280695

Tumor suppressor MMAC/PTEN inhibits cytokine-induced NFkappaB activation without interfering with the IkappaB degradation pathway

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=280695

Gamma interferon prevents the inhibitory effects of oxidative stress on host responses to Escherichia coli infection

28 September 2017

1 reference

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Ten years of gene targeting: targeted mouse mutants, from vector design to phenotype analysis

28 September 2017

1 reference

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Beyond 'knock-out' mice: new perspectives for the programmed modification of the mammalian genome.

28 September 2017

1 reference

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Functional redundancy of the nuclear factor kappa B inhibitors I kappa B alpha and I kappa B beta

28 September 2017

1 reference

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Autoregulation of I kappa B alpha activity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=280695

In vivo control of NF-kappa B activation by I kappa B alpha.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=280695

Inducible nuclear expression of newly synthesized I kappa B alpha negatively regulates DNA-binding and transcriptional activities of NF-kappa B.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=280695

Constitutive NF-kappa B activation, enhanced granulopoiesis, and neonatal lethality in I kappa B alpha-deficient mice

28 September 2017

1 reference

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Influence of lipopolysaccharide exposure on airway function and allergic responses in developing mice

28 September 2017

1 reference

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Signaling molecules of the NF-kappa B pathway shuttle constitutively between cytoplasm and nucleus.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=280695

Rel/NF-κB transcription factors and the control of apoptosis

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=280695

Rel/NF-kappa B and I kappa B factors in oncogenesis

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=280695

Rel/NF-kappa B and I kappa B proteins: an overview

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=280695

A gradient of cactus protein degradation establishes dorsoventral polarity in the Drosophila embryo

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=280695

The involvement of NF-kappa B in beta-interferon gene regulation reveals its role as widely inducible mediator of signal transduction

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=280695

Characterization of intestinal alkaline phosphatase expression and the tumorigenic potential of gamma-irradiated HeLa x fibroblast cell hybrids

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=280695

A lack of SUMO conjugation affects cNLS-dependent nuclear protein import in yeast.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=280695

Small ubiquitin-related modifier-1 (SUMO-1) modification of the glucocorticoid receptor

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=280695

Isolation of a novel SUMO protein from tomato that suppresses EIX-induced cell death.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=280695

Role of IkappaBalpha ubiquitination in signal-induced activation of NFkappaB in vivo

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=280695

A 65-kappaD subunit of active NF-kappaB is required for inhibition of NF-kappaB by I kappaB.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=280695

p300 Transcriptional Repression Is Mediated by SUMO Modification

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/14613580

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Rapid Up-regulation of IκBβ and Abrogation of NF-κB Activity in Peritoneal Macrophages Stimulated with Lipopolysaccharide

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/14613580

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/1476-4598-2-39

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14613580%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

21 December 2019

1 reference

9 September 2019

https://scigraph.springernature.com/pub.10.1186/1476-4598-2-39

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14613580%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

PubMed publication ID

14613580

1 reference