Regulation of nuclear translocation of forkhead transcription factor AFX by protein kinase B (Q24675116)

1

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H Konishi

2

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H Matsuzaki

3

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Y Ono

4

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Y Shirai

5

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N Saito

6

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T Kitamura

7

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W Ogawa

8

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M Kasuga

9

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U Kikkawa

10

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Y Nishizuka

Proceedings of the National Academy of Sciences of the United States of America

11

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language of work or name

English

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publication date

12 October 1999

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published in

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volume

96

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issue

21

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page(s)

11836-41

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cites work

Direct control of the Forkhead transcription factor AFX by protein kinase B

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Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

7 April 2017

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Expression of a constitutively active Akt Ser/Thr kinase in 3T3-L1 adipocytes stimulates glucose uptake and glucose transporter 4 translocation

7 April 2017

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Protein-protein interaction of zinc finger LIM domains with protein kinase C

7 April 2017

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The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans

7 April 2017

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Cloning and Characterization of Three Human Forkhead Genes That Comprise an FKHR-like Gene Subfamily

7 April 2017

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AF6q21, a novel partner of the MLL gene in t(6;11)(q21;q23), defines a forkhead transcriptional factor subfamily

7 April 2017

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Akt signaling: linking membrane events to life and death decisions

7 April 2017

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Cloning and characterization of AFX, the gene that fuses to MLL in acute leukemias with a t(X;11)(q13;q23)

7 April 2017

1 reference

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Phosphatidylinositol 3-kinase: structure and expression of the 110 kd catalytic subunit

7 April 2017

1 reference

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Caenorhabditis elegans Akt/PKB transduces insulin receptor-like signals from AGE-1 PI3 kinase to the DAF-16 transcription factor

7 April 2017

1 reference

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Requirement for activation of the serine-threonine kinase Akt (protein kinase B) in insulin stimulation of protein synthesis but not of glucose transport

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18373

daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans

7 April 2017

1 reference

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daf-2 , an Insulin Receptor-Like Gene That Regulates Longevity and Diapause in Caenorhabditis elegans

7 April 2017

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Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1

7 April 2017

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Molecular basis for the substrate specificity of protein kinase B; comparison with MAPKAP kinase-1 and p70 S6 kinase

7 April 2017

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A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans

7 April 2017

1 reference

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Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

7 April 2017

1 reference

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Dominant negative forms of Akt (protein kinase B) and atypical protein kinase Clambda do not prevent insulin inhibition of phosphoenolpyruvate carboxykinase gene transcription

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18373

PDGF induces an early and a late wave of PI 3-kinase activity, and only the late wave is required for progression through G1.

28 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18373

Three distinct mechanisms for translocation and activation of the delta subspecies of protein kinase C

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18373

Direct Visualization of the Translocation of the γ-Subspecies of Protein Kinase C in Living Cells Using Fusion Proteins with Green Fluorescent Protein

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18373

28 September 2017

Phosphoinositide kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18373

Activation of RAC-protein kinase by heat shock and hyperosmolarity stress through a pathway independent of phosphatidylinositol 3-kinase

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18373

Fusion of a fork head domain gene to PAX3 in the solid tumour alveolar rhabdomyosarcoma

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18373

Molecular cloning of rat RAC protein kinase alpha and beta and their association with protein kinase C zeta

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18373

Structure of 85 kDa subunit of human phosphatidylinositol 3-kinase analyzed by using monoclonal antibodies

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18373

Cell division arrest induced by phorbol ester in CHO cells overexpressing protein kinase C-delta subspecies

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18373

Role of kinases and the phosphatase calcineurin in the nuclear shuttling of transcription factor NF-AT4.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18373

Phosphorylation of serine 256 by protein kinase B disrupts transactivation by FKHR and mediates effects of insulin on insulin-like growth factor-binding protein-1 promoter activity through a conserved insulin response sequence

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18373

Negative regulation of the forkhead transcription factor FKHR by Akt.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18373

Insulin stimulates phosphorylation of the forkhead transcription factor FKHR on serine 253 through a Wortmannin-sensitive pathway

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18373

Protein kinase B (c-Akt): a multifunctional mediator of phosphatidylinositol 3-kinase activation.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18373

Phosphoinositide 3-kinase: the key switch mechanism in insulin signalling

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18373

NF-AT activation requires suppression of Crm1-dependent export by calcineurin

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/10518537

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Neurite outgrowth of PC12 cells is suppressed by wortmannin, a specific inhibitor of phosphatidylinositol 3-kinase

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/10518537

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The pleckstrin homology domain of RAC protein kinase associates with the regulatory domain of protein kinase C zeta

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/10518537

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.96.21.11836

1 reference

ADS bibcode

1999PNAS...9611836T

0 references

1 reference

1 reference

PubMed publication ID

10518537

1 reference