Microbe sensing, positive feedback loops, and the pathogenesis of inflammatory diseases (Q24647287)

Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide

Europe PubMed Central

title

Microbe sensing, positive feedback loops, and the pathogenesis of inflammatory diseases (English)

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language of work or name

English

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publication date

January 2009

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published in

Immunological Reviews

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volume

227

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issue

1

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page(s)

248-63

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cites work

1 reference

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Crystal structure of the TLR4-MD-2 complex with bound endotoxin antagonist Eritoran

7 April 2017

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IRAK-M is a negative regulator of Toll-like receptor signaling

7 April 2017

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Cutting edge: role of Toll-like receptor 1 in mediating immune response to microbial lipoproteins

7 April 2017

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IRAK-4: a novel member of the IRAK family with the properties of an IRAK-kinase

7 April 2017

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A Toll-like receptor recognizes bacterial DNA

7 April 2017

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Structural Basis of Toll-Like Receptor 3 Signaling with Double-Stranded RNA

7 April 2017

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Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

7 April 2017

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UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes

7 April 2017

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The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9

7 April 2017

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TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathway

7 April 2017

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IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

7 April 2017

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Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway

7 April 2017

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Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components

7 April 2017

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The interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signaling

7 April 2017

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CD36 is a sensor of diacylglycerides

7 April 2017

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Identification of Lps2 as a key transducer of MyD88-independent TIR signalling

7 April 2017

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Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway

7 April 2017

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Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response

7 April 2017

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Ubiquitin signalling in the NF-kappaB pathway

7 April 2017

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Inflammation and autoimmunity caused by a SHP1 mutation depend on IL-1, MyD88, and a microbial trigger

7 April 2017

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Fevers, genes, and innate immunity

27 September 2017

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Sensing of 'danger signals' and pathogen-associated molecular patterns defines binary signaling pathways 'upstream' of Toll

27 September 2017

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Ficolins: novel pattern recognition molecules of the innate immune response

27 September 2017

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Neo-ligands for innate immune receptors and the etiology of sterile inflammatory disease

27 September 2017

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Vesicular stomatitis virus glycoprotein G activates a specific antiviral Toll-like receptor 4-dependent pathway

27 September 2017

1 reference

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Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus.

27 September 2017

1 reference

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Details of Toll-like receptor:adapter interaction revealed by germ-line mutagenesis

27 September 2017

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CATERPILLERs, pyrin and hereditary immunological disorders

27 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713013

Crystal structure of human toll-like receptor 3 (TLR3) ectodomain

27 September 2017

1 reference

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An animal model of hemophagocytic lymphohistiocytosis (HLH): CD8+ T cells and interferon gamma are essential for the disorder

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713013

Endoplasmic reticulum chaperone gp96 is required for innate immunity but not cell viability

27 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713013

TNF-alpha induction by LPS is regulated posttranscriptionally via a Tpl2/ERK-dependent pathway

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713013

Analysis of Tlr4-mediated LPS signal transduction in macrophages by mutational modification of the receptor

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713013

Does properdin crosslink the cellular and the humoral immune response?

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713013

Mechanisms of endotoxin shock and endotoxin hypersensitivity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713013

Genetic Control of Leucocyte Responses to Endotoxin

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713013

B cell-specific deletion of protein-tyrosine phosphatase Shp1 promotes B-1a cell development and causes systemic autoimmunity.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713013

CD14 is required for MyD88-independent LPS signaling.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713013

Protection against autoimmune nephritis in MyD88-deficient MRL/lpr mice

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19120489

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Toll-like receptor 4 expression levels determine the degree of LPS-susceptibility in mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19120489

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A chemotactic receptor for val(ala)-gly-ser-glu on human

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19120489