Epigenetic mechanisms in drug addiction (Q24645709)

Trends in Molecular Medicine

Europe PubMed Central

title

Epigenetic mechanisms in drug addiction (English)

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2

Eric J Nestler

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author name string

William Renthal

series ordinal

1

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language of work or name

English

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publication date

August 2008

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published in

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volume

14

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issue

8

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page(s)

341-50

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cites work

Stress, dysregulation of drug reward pathways, and the transition to drug dependence

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Enzymatic activity associated with class II HDACs is dependent on a multiprotein complex containing HDAC3 and SMRT/N-CoR

7 April 2017

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ATF-2 has intrinsic histone acetyltransferase activity which is modulated by phosphorylation

7 April 2017

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7 April 2017

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The role of chromatin during transcription

7 April 2017

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Chromatin modifications and their function

7 April 2017

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Epigenetic programming by maternal behavior

7 April 2017

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The language of covalent histone modifications

7 April 2017

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A phosphatase cascade by which rewarding stimuli control nucleosomal response

7 April 2017

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Drug-induced epigenetic changes produce drug tolerance

7 April 2017

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Persistent alterations in mesolimbic gene expression with abstinence from cocaine self-administration

7 April 2017

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Genome regulation by polycomb and trithorax proteins

7 April 2017

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Circadian regulator CLOCK is a histone acetyltransferase

7 April 2017

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Class II histone deacetylases act as signal-responsive repressors of cardiac hypertrophy

7 April 2017

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Transcriptional regulation by the phosphorylation-dependent factor CREB

7 April 2017

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Delta FosB mediates epigenetic desensitization of the c-fos gene after chronic amphetamine exposure

7 April 2017

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Histone deacetylase 5 epigenetically controls behavioral adaptations to chronic emotional stimuli

7 April 2017

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Covalent modification of DNA regulates memory formation

7 April 2017

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Histone deacetylases 5 and 9 govern responsiveness of the heart to a subset of stress signals and play redundant roles in heart development

7 April 2017

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Identification of PSD-95 as a regulator of dopamine-mediated synaptic and behavioral plasticity

7 April 2017

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The Rpd3/Hda1 family of lysine deacetylases: from bacteria and yeast to mice and men

7 April 2017

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Phenotypic plasticity and the epigenetics of human disease

7 April 2017

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Recovery of learning and memory is associated with chromatin remodelling

7 April 2017

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Epigenetic regulation in psychiatric disorders

7 April 2017

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Mammalian sirtuins--emerging roles in physiology, aging, and calorie restriction

7 April 2017

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Sustained hippocampal chromatin regulation in a mouse model of depression and antidepressant action

7 April 2017

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Chromatin remodeling is a key mechanism underlying cocaine-induced plasticity in striatum

7 April 2017

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Genome-wide map of nucleosome acetylation and methylation in yeast

7 April 2017

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Heterochromatin and epigenetic control of gene expression

7 April 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753378

Drug-induced activation of dopamine D(1) receptor signaling and inhibition of class I/II histone deacetylase induce chromatin remodeling in reward circuitry and modulate cocaine-related behaviors

7 April 2017

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DNA methylation in the human cerebral cortex is dynamically regulated throughout the life span and involves differentiated neurons

27 September 2017

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Altered memory capacities and response to stress in p300/CBP-associated factor (PCAF) histone acetylase knockout mice

27 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753378

Transgenic mice expressing an inhibitory truncated form of p300 exhibit long-term memory deficits.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753378

Histone deacetylase inhibitors modulates the induction and expression of amphetamine-induced behavioral sensitization partially through an associated learning of the environment in mice

27 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753378

Chimeric DNA methyltransferases target DNA methylation to specific DNA sequences and repress expression of target genes.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753378

Altered attention and prefrontal cortex gene expression in rats after binge-like exposure to cocaine during adolescence

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753378

Histone H3 lysine 4 demethylation is a target of nonselective antidepressive medications

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753378

CREB-binding protein controls response to cocaine by acetylating histones at the fosB promoter in the mouse striatum

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753378

Histone H3 lysine 9 methylation and HP1gamma are associated with transcription elongation through mammalian chromatin

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753378

Maternal care as a model for experience-dependent chromatin plasticity?

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753378

Regulation of gene expression by chronic morphine and morphine withdrawal in the locus ceruleus and ventral tegmental area.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753378

Unmanageable motivation in addiction: a pathology in prefrontal-accumbens glutamate transmission

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753378

DeltaFosB: a molecular switch for long-term adaptation in the brain

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753378

Dopamine D2-like antagonists induce chromatin remodeling in striatal neurons through cyclic AMP-protein kinase A and NMDA receptor signaling

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753378

Histone modifications at gene promoter regions in rat hippocampus after acute and chronic electroconvulsive seizures.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753378

Activator of G protein signaling 3: a gatekeeper of cocaine sensitization and drug seeking.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753378

Regulation of gene expression and cocaine reward by CREB and ΔFosB

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753378

Controlling the double helix

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753378

Chronic cocaine-mediated changes in non-human primate nucleus accumbens gene expression.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753378

Expression of the transcription factor deltaFosB in the brain controls sensitivity to cocaine

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753378

Regulation of cocaine reward by CREB.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753378

Heritable gene repression through the action of a directed DNA methyltransferase at a chromosomal locus

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753378

Dynamic BDNF activity in nucleus accumbens with cocaine use increases self-administration and relapse

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753378

Glutamate induces histone H3 phosphorylation but not acetylation in striatal neurons: role of mitogen- and stress-activated kinase-1.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753378

Parsing molecular and behavioral effects of cocaine in mitogen- and stress-activated protein kinase-1-deficient mice.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753378

The histone tails of the nucleosome

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753378

Brain chromatin remodeling: a novel mechanism of alcoholism.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753378

DeltaFosB induction in orbitofrontal cortex mediates tolerance to cocaine-induced cognitive dysfunction.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753378

c-Fos facilitates the acquisition and extinction of cocaine-induced persistent changes.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753378

Antidepressant-like effects of the histone deacetylase inhibitor, sodium butyrate, in the mouse

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753378

Cocaine-induced locomotor activity and Fos expression in nucleus accumbens are sensitized for 6 months after repeated cocaine administration outside the home cage.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753378

Regulation of histone acetylation during memory formation in the hippocampus.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753378

Mapping global histone acetylation patterns to gene expression

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753378

A single infusion of brain-derived neurotrophic factor into the ventral tegmental area induces long-lasting potentiation of cocaine seeking after withdrawal.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753378

Differential gene expression in the rat caudate putamen after "binge" cocaine administration: advantage of triplicate microarray analysis

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753378

Neuronal activity-dependent nucleocytoplasmic shuttling of HDAC4 and HDAC5.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753378

Time-dependent increases in brain-derived neurotrophic factor protein levels within the mesolimbic dopamine system after withdrawal from cocaine: implications for incubation of cocaine craving.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753378

Effects of chronic exposure to cocaine are regulated by the neuronal protein Cdk5.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753378

Induction of a long-lasting AP-1 complex composed of altered Fos-like proteins in brain by chronic cocaine and other chronic treatments.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2753378

10.1016/J.MOLMED.2008.06.004

28 November 2018

Identifiers

DOI

1 reference

1 reference

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PubMed publication ID

18635399

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