The NRG1 gene is frequently silenced by methylation in breast cancers and is a strong candidate for the 8p tumour suppressor gene (Q24645371)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19802002%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

title

The NRG1 gene is frequently silenced by methylation in breast cancers and is a strong candidate for the 8p tumour suppressor gene (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19802002%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

0 references

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19802002%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Robert C. Stein

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19802002%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Ian Ellis

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19802002%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Carlos Caldas

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19802002%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

author name string

Y L Chua

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19802002%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Y Ito

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19802002%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

J C M Pole

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19802002%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

M J O'Hare

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19802002%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

A Murrell

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19802002%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

P A W Edwards

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19802002%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

S Newman

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19802002%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

language of work or name

English

0 references

publication date

5 October 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19802002%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19802002%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

volume

28

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19802002%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

issue

46

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19802002%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

page(s)

4041-4052

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19802002%20AND%20SRC:MED&resulttype=core&format=json

An integrated resource for genome-wide identification and analysis of human tissue-specific differentially methylated regions (tDMRs)

9 February 2020

cites work

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7 April 2017

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7 April 2017

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7 April 2017

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7 April 2017

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7 April 2017

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Multiple novel transcription initiation sites for NRG1

7 April 2017

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High-resolution array CGH clarifies events occurring on 8p in carcinogenesis

7 April 2017

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Role of ErbB4 in breast cancer

27 September 2017

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ErbB4/HER4: role in mammary gland development, differentiation and growth inhibition

27 September 2017

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The neuregulin family of genes and their multiple splice variants in breast cancer

27 September 2017

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High-resolution aCGH and expression profiling identifies a novel genomic subtype of ER negative breast cancer

27 September 2017

1 reference

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BEX2 is overexpressed in a subset of primary breast cancers and mediates nerve growth factor/nuclear factor-kappaB inhibition of apoptosis in breast cancer cell lines

27 September 2017

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Telomere dysfunction as a cause of genomic instability in Werner syndrome

27 September 2017

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Heregulin-dependent delay in mitotic progression requires HER4 and BRCA1.

27 September 2017

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Myoepithelial cells: pathology, cell separation and markers of myoepithelial differentiation

27 September 2017

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High-resolution analysis of chromosome rearrangements on 8p in breast, colon and pancreatic cancer reveals a complex pattern of loss, gain and translocation

27 September 2017

1 reference

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Human breast epithelial stem cells and their regulation.

27 September 2017

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Gene expression profiling of breast cell lines identifies potential new basal markers.

27 September 2017

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Neuregulin-regulated gene expression in mammary carcinoma cells

27 September 2017

1 reference

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A 1 Mb minimal amplicon at 8p11-12 in breast cancer identifies new candidate oncogenes

27 September 2017

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p300 regulates p53-dependent apoptosis after DNA damage in colorectal cancer cells by modulation of PUMA/p21 levels

27 September 2017

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A simple method for estimating global DNA methylation using bisulfite PCR of repetitive DNA elements

27 September 2017

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A recurrent chromosome translocation breakpoint in breast and pancreatic cancer cell lines targets the neuregulin/NRG1 gene

27 September 2017

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Neuregulins: functions, forms, and signaling strategies

27 September 2017

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Gamma-heregulin: a fusion gene of DOC-4 and neuregulin-1 derived from a chromosome translocation

27 September 2017

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gamma-heregulin is the product of a chromosomal translocation fusing the DOC4 and HGL/NRG1 genes in the MDA-MB-175 breast cancer cell line

27 September 2017

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The oncogene heregulin induces apoptosis in breast epithelial cells and tumors

27 September 2017

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Neu differentiation factor (NDF), a dominant oncogene, causes apoptosis in vitro and in vivo

27 September 2017

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γ-Heregulin: a novel heregulin isoform that is an autocrine growth factor for the human breast cancer cell line, MDA-MB-175

27 September 2017

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An apoptosis-inducing isoform of neu differentiation factor (NDF) identified using a novel screen for dominant, apoptosis-inducing genes

27 September 2017

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Sequential requirement of hepatocyte growth factor and neuregulin in the morphogenesis and differentiation of the mammary gland

27 September 2017

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Analysis of proviral integration in human mammary epithelial cell lines immortalized by retroviral infection with a temperature-sensitive SV40 T-antigen construct

27 September 2017

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Biologic effects of heregulin/neu differentiation factor on normal and malignant human breast and ovarian epithelial cells.

27 September 2017

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Induction of epithelial abnormalities that resemble human breast lesions by the expression of the neu/erbB-2 oncogene in reconstituted mouse mammary gland.

30 May 2018

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NRG1 gene rearrangements in clinical breast cancer: identification of an adjacent novel amplicon associated with poor prognosis

30 May 2018

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Epigenome analyses using BAC microarrays identify evolutionary conservation of tissue-specific methylation of SHANK3.

28 November 2018

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A Recurrent Chromosome Breakpoint in Breast Cancer at theNRG1/Neuregulin 1/HeregulinGene

28 November 2018

1 reference

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Chromosome arm 8p and cancer: a fragile hypothesis.

28 November 2018

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Stable suppression of tumorigenicity by virus-mediated RNA interference

28 November 2018

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The breast proto-oncogene, HRGalpha regulates epithelial proliferation and lobuloalveolar development in the mouse mammary gland

28 November 2018

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DNA methylation is a critical cell-intrinsic determinant of astrocyte differentiation in the fetal brain.

28 November 2018

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A new diploid nontumorigenic human breast epithelial cell line isolated and propagated in chemically defined medium.

28 November 2018

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Neuregulins and erbB receptor expression in adult human oligodendrocytes

28 November 2018

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Crossref

https://api.crossref.org/works/10.1038%2FONC.2009.259

The extracellular region of heregulin is sufficient to promote mammary gland proliferation and tumorigenesis but not apoptosis

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19802002

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Clonal analysis of expression of epithelial antigens in cultures of normal human breast

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19802002

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Heregulin induces in vivo proliferation and differentiation of mammary epithelium into secretory lobuloalveoli

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19802002

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/ONC.2009.259

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19802002%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

9 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19802002%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

PubMed publication ID

19802002

1 reference