IL-4R drives dedifferentiation, mitogenesis, and metastasis in rhabdomyosarcoma (Q24601302)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21536546%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

title

IL-4R drives dedifferentiation, mitogenesis, and metastasis in rhabdomyosarcoma (English)

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30 January 2020

1 reference

11

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30 January 2020

author name string

Tohru Hosoyama

1

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30 January 2020

Mohammed Imran Aslam

2

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30 January 2020

Jinu Abraham

3

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30 January 2020

Suresh I Prajapati

4

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30 January 2020

Koichi Nishijo

5

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30 January 2020

Joel E Michalek

6

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30 January 2020

Lee Ann Zarzabal

7

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30 January 2020

Laura D Nelon

8

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30 January 2020

Denis C Guttridge

9

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30 January 2020

Brian P Rubin

10

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30 January 2020

language of work or name

English

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publication date

1 May 2011

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30 January 2020

published in

Clinical Cancer Research

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30 January 2020

volume

17

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30 January 2020

issue

9

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30 January 2020

page(s)

2757-2766

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Preclinical efficacy and safety of pascolizumab (SB 240683): a humanized anti-interleukin-4 antibody with therapeutic potential in asthma

30 January 2020

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Cloning of the human IL-13R alpha1 chain and reconstitution with the IL4R alpha of a functional IL-4/IL-13 receptor complex

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IL-4 acts as a myoblast recruitment factor during mammalian muscle growth

7 April 2017

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Pax7 is required for the specification of myogenic satellite cells

7 April 2017

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IL-4 induces cathepsin protease activity in tumor-associated macrophages to promote cancer growth and invasion

7 April 2017

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NVP-BEZ235 as a new therapeutic option for sarcomas.

27 September 2017

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A novel role of interleukin-13 receptor alpha2 in pancreatic cancer invasion and metastasis

27 September 2017

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CD4(+) T cells regulate pulmonary metastasis of mammary carcinomas by enhancing protumor properties of macrophages

27 September 2017

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27 September 2017

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Untangling the complex web of IL-4- and IL-13-mediated signaling pathways

27 September 2017

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PDGFR-A is a therapeutic target in alveolar rhabdomyosarcoma

27 September 2017

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MyoD and the transcriptional control of myogenesis

27 September 2017

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Antitumor activity of the insulin-like growth factor-I receptor kinase inhibitor NVP-AEW541 in musculoskeletal tumors.

27 September 2017

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Pax3:Fkhr interferes with embryonic Pax3 and Pax7 function: implications for alveolar rhabdomyosarcoma cell of origin.

27 September 2017

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Alveolar rhabdomyosarcomas in conditional Pax3:Fkhr mice: cooperativity of Ink4a/ARF and Trp53 loss of function.

27 September 2017

1 reference

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Interleukin-4 receptor signaling pathways in asthma pathogenesis

27 September 2017

1 reference

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Pax7 directs postnatal renewal and propagation of myogenic satellite cells but not their specification.

27 September 2017

1 reference

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Intergroup rhabdomyosarcoma study-IV: results for patients with nonmetastatic disease

27 September 2017

1 reference

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Insulin-like growth factor I synergizes with interleukin 4 for hematopoietic cell proliferation independent of insulin receptor substrate expression

27 September 2017

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Reduced differentiation potential of primary MyoD-/- myogenic cells derived from adult skeletal muscle

27 September 2017

1 reference

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Antisense-mediated reduction in insulin-like growth factor-I receptor expression suppresses the malignant phenotype of a human alveolar rhabdomyosarcoma

27 September 2017

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Interleukin 4 signals through two related pathways

27 September 2017

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27 September 2017

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27 September 2017

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Receptor for interleukin 13. Interaction with interleukin 4 by a mechanism that does not involve the common gamma chain shared by receptors for interleukins 2, 4, 7, 9, and 15.

30 May 2018

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Opposing control of rhabdomyosarcoma growth and differentiation by myogenin and interleukin 4.

30 May 2018

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Convection-enhanced delivery of cintredekin besudotox (interleukin-13-PE38QQR) followed by radiation therapy with and without temozolomide in newly diagnosed malignant gliomas: phase 1 study of final safety results

28 November 2018

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28 November 2018

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Both hepatocyte growth factor (HGF) and stromal-derived factor-1 regulate the metastatic behavior of human rhabdomyosarcoma cells, but only HGF enhances their resistance to radiochemotherapy.

28 November 2018

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28 November 2018

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Interleukin-13 receptor alpha' but not alpha chain: a functional component of interleukin-4 receptors

28 November 2018

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A randomized, controlled, phase 2 study of AMG 317, an IL-4Ralpha antagonist, in patients with asthma

28 November 2018

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12 December 2020

Cutting edge: STAT6-deficient mice have enhanced tumor immunity to primary and metastatic mammary carcinoma

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12 December 2020

NKT cell-mediated repression of tumor immunosurveillance by IL-13 and the IL-4R-STAT6 pathway

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12 December 2020

Deficiency in rhabdomyosarcomas of a factor required for MyoD activity and myogenesis

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12 December 2020

The IL-13 receptor structure differs on various cell types and may share more than one component with IL-4 receptor

1 reference

12 December 2020

The interleukin-4 site-2 epitope determining binding of the common receptor gamma chain

1 reference

12 December 2020

10.1158/1078-0432.CCR-10-3445

Identifiers

DOI

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21536546%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21536546%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

PubMed publication ID

21536546

2 references