An induced rebinding model of antigen discrimination (Q24568025)

PubMed

PubMed publication ID

24636916

Philip Anton van der Merwe

7 November 2023

series ordinal

2

object named as

P Anton van der Merwe

author given names

P Anton

author last names

van der Merwe

1 reference

PubMed

PubMed publication ID

24636916

Creative Commons Attribution 3.0 Unported

7 November 2023

language of work or name

English

0 references

publication date

April 2014

0 references

1 April 2014

4 references

31 July 2019

19 September 2019

15 December 2019

4 August 2020

4 references

31 July 2019

19 September 2019

15 December 2019

4 August 2020

35

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issue

4

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page(s)

153-8

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copyright license

4 references

31 July 2019

19 September 2019

15 December 2019

Modeling T cell antigen discrimination based on feedback control of digital ERK responses

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0 references

1 reference

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Regulation of T Cell Receptor Activation by Dynamic Membrane Binding of the CD3ɛ Cytoplasmic Tyrosine-Based Motif

24 March 2017

1 reference

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Late Arrival: Recruiting Coreceptors to the T Cell Receptor Complex

24 March 2017

1 reference

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Two-Stage Cooperative T Cell Receptor-Peptide Major Histocompatibility Complex-CD8 Trimolecular Interactions Amplify Antigen Discrimination

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989030

T cell receptor-proximal signals are sustained in peripheral microclusters and terminated in the central supramolecular activation cluster

24 March 2017

1 reference

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T cell antigen receptor activation and actin cytoskeleton remodeling

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989030

Phenotypic model for early T-cell activation displaying sensitivity, specificity, and antagonism.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989030

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27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989030

Antigen recognition is facilitated by invadosome-like protrusions formed by memory/effector T cells

27 September 2017

1 reference

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Kinetics and mechanics of two-dimensional interactions between T cell receptors and different activating ligands

27 September 2017

1 reference

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Quantum dot fluorescence characterizes the nanoscale organization of T cell receptors for antigen

27 September 2017

1 reference

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Basic residues in the T-cell receptor ζ cytoplasmic domain mediate membrane association and modulate signaling

27 September 2017

1 reference

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Functional nanoscale organization of signaling molecules downstream of the T cell antigen receptor

27 September 2017

1 reference

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Transforming binding affinities from three dimensions to two with application to cadherin clustering

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1 reference

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Antigen potency and maximal efficacy reveal a mechanism of efficient T cell activation

27 September 2017

1 reference

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Mechanisms for T cell receptor triggering

27 September 2017

1 reference

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Peptide-MHC heterodimers show that thymic positive selection requires a more restricted set of self-peptides than negative selection

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989030

Fast on-rates allow short dwell time ligands to activate T cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989030

The kinetics of two-dimensional TCR and pMHC interactions determine T-cell responsiveness.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989030

TCR-peptide-MHC interactions in situ show accelerated kinetics and increased affinity.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989030

Dependence of T cell antigen recognition on T cell receptor-peptide MHC confinement time

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989030

TCR and Lat are expressed on separate protein islands on T cell membranes and concatenate during activation.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989030

A role for rebinding in rapid and reliable T cell responses to antigen

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989030

The impact of TCR-binding properties and antigen presentation format on T cell responsiveness

27 September 2017

1 reference

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Memory in receptor-ligand-mediated cell adhesion

27 September 2017

1 reference

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Single-molecule level analysis of the subunit composition of the T cell receptor on live T cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989030

Thymic selection threshold defined by compartmentalization of Ras/MAPK signalling

27 September 2017

1 reference

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Effects of receptor clustering on ligand dissociation kinetics: theory and simulations.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989030

Coexistence of multivalent and monovalent TCRs explains high sensitivity and wide range of response

27 September 2017

1 reference

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Cooperative enhancement of specificity in a lattice of T cell receptors

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989030

Increased TCR avidity after T cell activation: a mechanism for sensing low-density antigen

27 September 2017

1 reference

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The dynamics of T cell receptor signaling: complex orchestration and the key roles of tempo and cooperation

27 September 2017

1 reference

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Kinetic proofreading in T-cell receptor signal transduction

27 September 2017

1 reference

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Why do some T cell receptor cytoplasmic domains associate with the plasma membrane?

27 September 2017

1 reference

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Membrane clustering and the role of rebinding in biochemical signaling

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989030

Spatial and temporal dynamics of T cell receptor signaling with a photoactivatable agonist

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989030

Increased sensitivity of antigen-experienced T cells through the enrichment of oligomeric T cell receptor complexes

30 May 2018

1 reference

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Taking T cells beyond the diffraction limit

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989030

DySCo: quantitating associations of membrane proteins using two-color single-molecule tracking.

28 November 2018

1 reference

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Serial rebinding of ligands to clustered receptors as exemplified by bacterial chemotaxis

28 November 2018

1 reference

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TCR ligand discrimination is enforced by competing ERK positive and SHP-1 negative feedback pathways

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989030

Efficient T cell activation requires an optimal dwell-time of interaction between the TCR and the pMHC complex

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989030

Quantitative analysis of the contribution of TCR/pepMHC affinity and CD8 to T cell activation

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24636916

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12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.IT.2014.02.002

1 reference

release_5jhcudxnrjbbximhsfsr6vycfe

Fatcat ID

0 references

1 reference

1 reference

PubMed publication ID

24636916

1 reference