Anticonvulsant potencies of the enantiomers of the neurosteroids androsterone and etiocholanolone exceed those of the natural forms (Q24564596)

ChEBI release 2020-05-28

1 reference

1

Dorota Zolkowska

Dorota

Zolkowska

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24705905%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

2

Ashish Dhir

Ashish

Dhir

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24705905%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

5

Michael A Rogawski

Michael A

Rogawski

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24705905%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

4

Douglas F Covey

Douglas F

Covey

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24705905%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Kathiresan Krishnan

3

Kathiresan

Krishnan

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24705905%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

language of work or name

English

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publication date

September 2014

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number of pages

8

1 reference

based on heuristic

inferred from page(s)

published in

Psychopharmacology

1 reference

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13 June 2020

volume

231

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13 June 2020

issue

17

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13 June 2020

page(s)

3325-3332

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24705905%20AND%20SRC:MED&resulttype=core&format=json

Anticonvulsant activity of androsterone and etiocholanolone.

13 June 2020

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1 reference

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Progress report on new antiepileptic drugs: a summary of the Eleventh Eilat Conference (EILAT XI)

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Neurosteroids — Endogenous Regulators of Seizure Susceptibility and Role in the Treatment of Epilepsy

24 March 2017

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7 January 2021

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Neurosteroid analogues. 17. Inverted binding orientations of androsterone enantiomers at the steroid potentiation site on γ-aminobutyric acid type A receptors

24 March 2017

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ent-Steroids: novel tools for studies of signaling pathways

27 September 2017

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Conserved site for neurosteroid modulation of GABA A receptors

27 September 2017

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Neurosteroid analogues. 12. Potent enhancement of GABA-mediated chloride currents at GABAA receptors by ent-androgens

27 September 2017

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Allopregnanolone analogs that positively modulate GABA receptors protect against partial seizures induced by 6-Hz electrical stimulation in mice

27 September 2017

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Stress-induced deoxycorticosterone-derived neurosteroids modulate GABA(A) receptor function and seizure susceptibility.

27 September 2017

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Anticonvulsant activity of neurosteroids: correlation with gamma-aminobutyric acid-evoked chloride current potentiation

27 September 2017

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Stereoselectivity and Affinity in Molecular Pharmacology

27 September 2017

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Enantioselectivity of steroid-induced gamma-aminobutyric acidA receptor modulation and anesthesia.

27 September 2017

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Steroid anesthetics and naturally occurring analogs modulate the gamma-aminobutyric acid receptor complex at a site distinct from barbiturates

30 May 2018

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Antiepileptic drug development: II. Anticonvulsant drug screening

30 May 2018

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Conformationally constrained anesthetic steroids that modulate GABA(A) receptors

30 May 2018

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Neurosteroids: endogenous allosteric modulators of GABA(A) receptors.

21 January 2018

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Enhanced anticonvulsant activity of ganaxolone after neurosteroid withdrawal in a rat model of catamenial epilepsy.

21 January 2018

1 reference

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Enantioselectivity of pregnanolone-induced gamma-aminobutyric acid(A) receptor modulation and anesthesia

28 November 2018

1 reference

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Finasteride, a 5alpha-reductase inhibitor, blocks the anticonvulsant activity of progesterone in mice.

28 November 2018

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Correlation of neuroactive steroid modulation of [35S]t-butylbicyclophosphorothionate and [3H]flunitrazepam binding and gamma-aminobutyric acidA receptor function.

28 November 2018

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Characterization of steroid interactions with gamma-aminobutyric acid receptor-gated chloride ion channels: evidence for multiple steroid recognition sites

28 November 2018

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10.1007/S00213-014-3546-X

28 November 2018

Identifiers

DOI

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24705905%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

13 June 2020

1009953443

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Fatcat ID

release_b6amj4zhone4jjigqdns2sd6ji

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24705905%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

PubMed publication ID

24705905

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24705905%20AND%20SRC:MED&resulttype=core&format=json