Sema4D/plexin-B1 activates GSK-3beta through R-Ras GAP activity, inducing growth cone collapse (Q24550822)

4

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author name string

Yuri Ito

1

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Izumi Oinuma

2

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Hironori Katoh

3

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Manabu Negishi

Direct interaction of Rnd1 with Plexin-B1 regulates PDZ-RhoGEF-mediated Rho activation by Plexin-B1 and induces cell contraction in COS-7 cells

5

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language of work or name

English

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publication date

July 2006

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published in

EMBO Reports

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volume

7

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issue

7

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page(s)

704-9

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cites work

1 reference

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Binding of the adenomatous polyposis coli protein to microtubules increases microtubule stability and is regulated by GSK3 beta phosphorylation

24 March 2017

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Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates

24 March 2017

1 reference

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A New Member of the Rho Family, Rnd1, Promotes Disassembly of Actin Filament Structures and Loss of Cell Adhesion

24 March 2017

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The phosphoinositide 3-kinase pathway

24 March 2017

1 reference

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The semaphorin genes encode a family of transmembrane and secreted growth cone guidance molecules

24 March 2017

1 reference

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The Semaphorin 4D receptor Plexin-B1 is a GTPase activating protein for R-Ras

24 March 2017

1 reference

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CRMP-2 binds to tubulin heterodimers to promote microtubule assembly

24 March 2017

1 reference

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Plexin-B1 directly interacts with PDZ-RhoGEF/LARG to regulate RhoA and growth cone morphology

24 March 2017

1 reference

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The effector loop and prenylation site of R-Ras are involved in the regulation of integrin function

24 March 2017

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Cdc42 regulates GSK-3beta and adenomatous polyposis coli to control cell polarity

24 March 2017

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FARP2 triggers signals for Sema3A-mediated axonal repulsion

24 March 2017

1 reference

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GSK-3beta regulates phosphorylation of CRMP-2 and neuronal polarity.

27 September 2017

1 reference

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Activation of phosphoinositide 3-kinase gamma by Ras.

27 September 2017

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Plexina1 autoinhibition by the plexin sema domain.

27 September 2017

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Activated R-ras, Rac1, PI 3-kinase and PKCepsilon can each restore cell spreading inhibited by isolated integrin beta1 cytoplasmic domains

27 September 2017

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R-Ras signals through specific integrin alpha cytoplasmic domains to promote migration and invasion of breast epithelial cells

27 September 2017

1 reference

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A novel GTPase-activating protein for R-Ras

27 September 2017

1 reference

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GSK-3 phosphorylation of the Alzheimer epitope within collapsin response mediator proteins regulates axon elongation in primary neurons.

27 September 2017

1 reference

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An inactive pool of GSK-3 at the leading edge of growth cones is implicated in Semaphorin 3A signaling.

30 May 2018

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Alpha2-chimaerin, cyclin-dependent Kinase 5/p35, and its target collapsin response mediator protein-2 are essential components in semaphorin 3A-induced growth-cone collapse.

30 May 2018

1 reference

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R-Ras can activate the phosphoinositide 3-kinase but not the MAP kinase arm of the Ras effector pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EMBOR.7400737

Inhibition of glycogen synthase kinase 3beta in sensory neurons in culture alters filopodia dynamics and microtubule distribution in growth cones.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EMBOR.7400737

Semaphorin3A signalling is mediated via sequential Cdk5 and GSK3beta phosphorylation of CRMP2: implication of common phosphorylating mechanism underlying axon guidance and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EMBOR.7400737

Integrin activation by R-ras.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EMBOR.7400737

PTEN couples Sema3A signalling to growth cone collapse.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1500830

Plexin signaling hampers integrin-based adhesion, leading to Rho-kinase independent cell rounding, and inhibiting lamellipodia extension and cell motility

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1500830

Measurement of GTP-bound Ras-like GTPases by activation-specific probes

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1500830

Molecular dissection of the semaphorin 4D receptor plexin-B1-stimulated R-Ras GTPase-activating protein activity and neurite remodeling in hippocampal neurons

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16799460

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/SJ.EMBOR.7400737

1 reference

1 reference

1 reference

PubMed publication ID

16799460

1 reference