p68 RNA helicase is an essential human splicing factor that acts at the U1 snRNA-5' splice site duplex (Q24537595)

6 July 2017

title

p68 RNA helicase is an essential human splicing factor that acts at the U1 snRNA-5' splice site duplex (English)

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6 July 2017

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Zhi-Ren Liu

1

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6 July 2017

language of work or name

English

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publication date

1 August 2002

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full work available at URL

6 July 2017

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC133941

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published in

Molecular and Cellular Biology

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6 July 2017

volume

22

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6 July 2017

issue

15

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6 July 2017

page(s)

5443-5450

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The apoptosis-promoting factor TIA-1 is a regulator of alternative pre-mRNA splicing

6 July 2017

cites work

1 reference

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Purification and identification of p68 RNA helicase acting as a transcriptional coactivator specific for the activation function 1 of human estrogen receptor alpha

24 March 2017

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Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex

24 March 2017

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The human U5-200kD DEXH-box protein unwinds U4/U6 RNA duplices in vitro

24 March 2017

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The human U5 snRNP-specific 100-kD protein is an RS domain-containing, putative RNA helicase with significant homology to the yeast splicing factor Prp28p

24 March 2017

1 reference

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p68 RNA helicase: identification of a nucleolar form and cloning of related genes containing a conserved intron in yeasts

24 March 2017

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Identification and characterization of yUAP/Sub2p, a yeast homolog of the essential human pre-mRNA splicing factor hUAP56

24 March 2017

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Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families.

24 March 2017

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RNA unwinding in U4/U6 snRNPs requires ATP hydrolysis and the DEIH-box splicing factor Brr2

24 March 2017

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Mechanical Devices of the Spliceosome: Motors, Clocks, Springs, and Things

24 March 2017

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Cross-intron bridging interactions in the yeast commitment complex are conserved in mammals

24 March 2017

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Identification of a novel component of the nonsense-mediated mRNA decay pathway by use of an interacting protein screen

24 March 2017

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The 100-kda U5 snRNP protein (hPrp28p) contacts the 5' splice site through its ATPase site

24 March 2017

1 reference

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The protein family of RNA helicases

24 March 2017

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Dynamic RNA-RNA interactions in the spliceosome

24 March 2017

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D-E-A-D protein family of putative RNA helicases

7 April 2017

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The ATPase, RNA unwinding, and RNA binding activities of recombinant p68 RNA helicase

7 April 2017

1 reference

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Pre-mRNA splicing in the new millennium

27 September 2017

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A new twist on RNA helicases: DExH/D box proteins as RNPases

27 September 2017

1 reference

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Multiple roles for the yeast SUB2/yUAP56 gene in splicing

27 September 2017

1 reference

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RNA helicase dynamics in pre-mRNA splicing

27 September 2017

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Mechanisms of fidelity in pre-mRNA splicing

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133941

A chicken embryo protein related to the mammalian DEAD box protein p68 is tightly associated with the highly purified protein-RNA complex of 5-MeC-DNA glycosylase

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133941

The first ATPase domain of the yeast 246-kDa protein is required for in vivo unwinding of the U4/U6 duplex

27 September 2017

1 reference

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Flipping the switch to an active spliceosome

27 September 2017

1 reference

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Detection of a novel ATP-dependent cross-linked protein at the 5' splice site-U1 small nuclear RNA duplex by methylene blue-mediated photo-cross-linking

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133941

An intron element modulating 5' splice site selection in the hnRNP A1 pre-mRNA interacts with hnRNP A1.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133941

A novel human homologue of a dead-box RNA helicase family

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133941

RNA splicing. U2 fulfils a commitment

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133941

Rearrangement of snRNA structure during assembly and function of the spliceosome

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133941

Autoregulation of expression of the yeast Dbp2p ‘DEAD-box’ protein is mediated by sequences in the conserved DBP2 intron

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133941

Split genes and RNA splicing

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133941

Cellular proteins reactive with monoclonal antibodies directed against simian virus 40 T-antigen

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133941

An RNA switch at the 5' splice site requires ATP and the DEAD box protein Prp28p

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133941

Spliceosome assembly: the unwinding role of DEAD-box proteins

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133941

Expression of the 'dead box' RNA helicase p68 is developmentally and growth regulated and correlates with organ differentiation/maturation in the fetus

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133941

The DEAH-box splicing factor Prp16 unwinds RNA duplexes in vitro

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133941

Detection of double-stranded RNA-protein interactions by methylene blue-mediated photo-crosslinking

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133941

Molecular biology. RNP remodeling with DExH/D boxes

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133941

Active disruption of an RNA-protein interaction by a DExH/D RNA helicase

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133941

Crosslinking of the U5 snRNP-specific 116-kDa protein to RNA hairpins that block step 2 of splicing

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133941

SV40 large T shares an antigenic determinant with a cellular protein of molecular weight 68,000.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133941

Specific alterations of U1-C protein or U1 small nuclear RNA can eliminate the requirement of Prp28p, an essential DEAD box splicing factor

29 November 2018

1 reference

PubMed

12 December 2020

Interactions of small nuclear RNA's with precursor messenger RNA during in vitro splicing

1 reference

PubMed

12 December 2020

1 reference

12 December 2020

Splicing factor Prp8 governs U4/U6 RNA unwinding during activation of the spliceosome

1 reference

PubMed

12 December 2020

10.1128/MCB.22.15.5443-5450.2002

Identifiers

DOI

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6 July 2017

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6 July 2017

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