Deleted in liver cancer 2 (DLC2) suppresses cell transformation by means of inhibition of RhoA activity (Q24533631)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16217026%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

title

Deleted in liver cancer 2 (DLC2) suppresses cell transformation by means of inhibition of RhoA activity (English)

1 reference

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7 January 2020

1 reference

3

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7 January 2020

Irene Oi-lin Ng

7

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7 January 2020

author name string

Thomas Ho-Yin Leung

1

1 reference

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7 January 2020

Yick-Pang Ching

2

1 reference

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7 January 2020

Chun-Ming Wong

4

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7 January 2020

Tai-On Yau

5

1 reference

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7 January 2020

Dong-Yan Jin

6

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7 January 2020

language of work or name

English

0 references

publication date

10 October 2005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16217026%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

7 January 2020

published in

1 reference

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7 January 2020

volume

102

1 reference

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7 January 2020

issue

42

1 reference

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7 January 2020

page(s)

15207-15212

1 reference

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Rho GTPases and the Actin Cytoskeleton

7 January 2020

cites work

1 reference

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The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

24 March 2017

1 reference

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The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

24 March 2017

1 reference

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Genetic and epigenetic alterations of DLC-1 gene in hepatocellular carcinoma

24 March 2017

1 reference

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Cloning, characterization, and chromosomal localization of a gene frequently deleted in human liver cancer (DLC-1) homologous to rat RhoGAP

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1250229

The Rat Myosin myr 5 Is a GTPase-activating Protein for Rho In Vivo: Essential Role of Arginine 1695

24 March 2017

1 reference

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Small GTP-binding proteins and the regulation of the actin cytoskeleton

24 March 2017

1 reference

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Cell motility mediated by rho and rho-associated protein kinase plays a critical role in intrahepatic metastasis of human hepatocellular carcinoma

24 March 2017

1 reference

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24 March 2017

RHO-GTPases and cancer

1 reference

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An Essential Role for Rho, Rac, and Cdc42 GTPases in Cell Cycle Progression Through G 1

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1250229

Anti-RhoA and anti-RhoC siRNAs inhibit the proliferation and invasiveness of MDA-MB-231 breast cancer cells in vitro and in vivo.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1250229

Characterization of a novel GTPase-activating protein associated with focal adhesions and the actin cytoskeleton

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1250229

Deleted in liver cancer (DLC) 2 encodes a RhoGAP protein with growth suppressor function and is underexpressed in hepatocellular carcinoma

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1250229

Rho GTPases in transformation and metastasis.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1250229

Morphological changes and detachment of adherent cells induced by p122, a GTPase-activating protein for Rho.

27 September 2017

1 reference

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Rho, rac and cdc42 GTPases: regulators of actin structures, cell adhesion and motility

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1250229

A role for Rho in Ras transformation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1250229

Cellular responses regulated by rho-related small GTP-binding proteins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1250229

Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1250229

Signal transduction through small GTPases—A tale of two GAPs

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1250229

A novel testicular RhoGAP-domain protein induces apoptosis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1250229

An essential part for Rho-associated kinase in the transcellular invasion of tumor cells.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1250229

Signals from Ras and Rho GTPases interact to regulate expression of p21Waf1/Cip1.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1250229

ADP-ribosylation of the rhoA gene product by botulinum C3 exoenzyme causes Swiss 3T3 cells to accumulate in the G1 phase of the cell cycle.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1250229

Rho GTPases are over-expressed in human tumors.

30 May 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0504501102

Rho: a connection between membrane receptor signalling and the cytoskeleton

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0504501102

Inhibitory effect of Y-27632, a ROCK inhibitor, on progression of rat liver fibrosis in association with inactivation of hepatic stellate cells

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0504501102

DLC-1 is deleted in primary hepatocellular carcinoma and exerts inhibitory effects on the proliferation of hepatoma cell lines with deleted DLC-1

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16217026

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Overexpression of RhoA mRNA is associated with advanced stage in testicular germ cell tumour

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16217026

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Significant association of Rho/ROCK pathway with invasion and metastasis of bladder cancer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16217026

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0504501102

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16217026%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

ADS bibcode

2005PNAS..10215207L

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16217026%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

PubMed publication ID

16217026

2 references