Regulation of insulin secretion by SIRT4, a mitochondrial ADP-ribosyltransferase (Q24338198)

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3 January 2020

title

Regulation of insulin secretion by SIRT4, a mitochondrial ADP-ribosyltransferase (English)

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GOA release 2020-03-11

NAD-dependent protein deacetylase activity

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GOA release 2020-03-11

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7

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Eric Verdin

8

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author name string

Nidhi Ahuja

1

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3 January 2020

Bjoern Schwer

2

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Stefania Carobbio

3

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David Waltregny

4

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Brian J North

5

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Vincenzo Castronovo

6

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language of work or name

English

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publication date

22 August 2007

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Journal of Biological Chemistry

3 January 2020

published in

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volume

282

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issue

46

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page(s)

33583-33592

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Stimulus-secretion coupling in pancreatic beta cells.

3 January 2020

cites work

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7 January 2021

Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity

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7 January 2021

Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins

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7 January 2021

The mitochondrial processing peptidase: function and specificity

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7 January 2021

Alzheimer's beta-amyloid peptide specifically interacts with and is degraded by insulin degrading enzyme

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7 January 2021

Direct thyroid hormone signalling via ADP-ribosylation controls mitochondrial nucleotide transport and membrane leakiness by changing the conformation of the adenine nucleotide transporter

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7 January 2021

The Sir 2 family of protein deacetylases

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7 January 2021

SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells

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7 January 2021

Increased dosage of mammalian Sir2 in pancreatic beta cells enhances glucose-stimulated insulin secretion in mice

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7 January 2021

Nucleotide exchange in mitochondria: insight at a molecular level

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7 January 2021

Partial loss-of-function mutations in insulin-degrading enzyme that induce diabetes also impair degradation of amyloid beta-protein

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7 January 2021

Crystal structure of a SIR2 homolog-NAD complex

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7 January 2021

Negative control of p53 by Sir2alpha promotes cell survival under stress

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7 January 2021

hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase

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7 January 2021

Mammalian SIRT1 represses forkhead transcription factors

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7 January 2021

Protein sorting: recognizing mitochondrial presequences

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7 January 2021

Mechanisms of protein import into mitochondria

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7 January 2021

How mitochondria import hydrophilic and hydrophobic proteins.

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7 January 2021

Structure of a Sir2 enzyme bound to an acetylated p53 peptide

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7 January 2021

The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase

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7 January 2021

Sir2 regulates skeletal muscle differentiation as a potential sensor of the redox state

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7 January 2021

Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans

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7 January 2021

A mouse model for mitochondrial myopathy and cardiomyopathy resulting from a deficiency in the heart/muscle isoform of the adenine nucleotide translocator

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7 January 2021

Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase

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7 January 2021

Alternative translation initiation generates a novel isoform of insulin-degrading enzyme targeted to mitochondria

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7 January 2021

The rapid response of isolated mitochondrial particles to 0.1 nM-tri-iodothyronine correlates with the ADP-ribosylation of a single inner-membrane protein

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7 January 2021

Molecular mechanisms and regulation of insulin exocytosis as a paradigm of endocrine secretion

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7 January 2021

Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo

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7 January 2021

Amyloid-beta peptide levels in brain are inversely correlated with insulysin activity levels in vivo

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7 January 2021

SIRT3, a human SIR2 homologue, is an NAD-dependent deacetylase localized to mitochondria

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7 January 2021

Mouse Sir2 homolog SIRT6 is a nuclear ADP-ribosyltransferase

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7 January 2021

SIRT3, a mitochondrial sirtuin deacetylase, regulates mitochondrial function and thermogenesis in brown adipocytes

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7 January 2021

The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase

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7 January 2021

Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins

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7 January 2021

Regulation of glutamate dehydrogenase by reversible ADP-ribosylation in mitochondria

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7 January 2021

Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence

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7 January 2021

A chromosomal SIR2 homologue with both histone NAD-dependent ADP-ribosyltransferase and deacetylase activities is involved in DNA repair in Trypanosoma brucei

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7 January 2021

Insulin-degrading enzyme identified as a candidate diabetes susceptibility gene in GK rats

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7 January 2021

Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase

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7 January 2021

Evidence for genetic linkage of Alzheimer's disease to chromosome 10q

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7 January 2021

Metabolic coupling factors in pancreatic beta-cell signal transduction

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7 January 2021

The Sir2 family of protein deacetylases

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7 January 2021

Sirtuins: Sir2-related NAD-dependent protein deacetylases

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7 January 2021

Establishment of 2-mercaptoethanol-dependent differentiated insulin-secreting cell lines

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7 January 2021

Glucose Sensitivity and Metabolism-Secretion Coupling Studied during Two-Year Continuous Culture in INS-1E Insulinoma Cells

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7 January 2021

Sirt1 regulates insulin secretion by repressing UCP2 in pancreatic beta cells

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7 January 2021

Effects of depletion of mitochondrial DNA in metabolism secretion coupling in INS-1 cells.

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7 January 2021

Identifiers

DOI

10.1074/JBC.M705488200

2 references

Consolidated OpenCitations Corpus – April 2017

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3 January 2020

1 reference

Consolidated OpenCitations Corpus – April 2017

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Consolidated OpenCitations Corpus – April 2017