Methylation by protein arginine methyltransferase 1 increases stability of Axin, a negative regulator of Wnt signaling (Q24337495)

regulation of gene expression

GOA release 2020-03-11

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E-h Jho

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22 November 2024

author name string

B. Cha

1

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22 November 2024

W. Kim

2

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22 November 2024

Y. K. Kim

3

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22 November 2024

B. N. Hwang

4

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22 November 2024

S. Y. Park

5

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22 November 2024

J. W. Yoon

6

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W. S. Park

7

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J. W. Cho

8

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22 November 2024

M. T. Bedford

9

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22 November 2024

language of work or name

English

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publication date

19 May 2011

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17 January 2011

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full work available at URL

22 November 2024

https://www.nature.com/articles/onc2010610.pdf

file format

Portable Document Format

online access status

open access

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https://www.nature.com/articles/onc2010610.pdf

22 November 2024

file format

Portable Document Format

1 reference

https://api.crossref.org/works/10.1038/ONC.2010.610

https://www.nature.com/articles/onc2010610

22 November 2024

1 reference

https://api.crossref.org/works/10.1038/ONC.2010.610

22 November 2024

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30

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issue

20

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page(s)

2379-89

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cites work

Arginine methylation inhibits the binding of proline-rich ligands to Src homology 3, but not WW, domains

1 reference

https://api.crossref.org/works/10.1038/ONC.2010.610

Structural basis for recruitment of glycogen synthase kinase 3beta to the axin-APC scaffold complex

20 April 2017

1 reference

https://api.crossref.org/works/10.1038/ONC.2010.610

Casein kinase 1 gamma couples Wnt receptor activation to cytoplasmic signal transduction

20 April 2017

1 reference

https://api.crossref.org/works/10.1038/ONC.2010.610

Domains of axin involved in protein-protein interactions, Wnt pathway inhibition, and intracellular localization

20 April 2017

1 reference

https://api.crossref.org/works/10.1038/ONC.2010.610

Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling

20 April 2017

1 reference

https://api.crossref.org/works/10.1038/ONC.2010.610

A GSK3beta phosphorylation site in axin modulates interaction with beta-catenin and Tcf-mediated gene expression

20 April 2017

1 reference

https://api.crossref.org/works/10.1038/ONC.2010.610

SUMOylation target sites at the C terminus protect Axin from ubiquitination and confer protein stability

20 April 2017

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beta-catenin destruction complex: insights and questions from a structural perspective

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The human F box protein beta-Trcp associates with the Cul1/Skp1 complex and regulates the stability of beta-catenin.

20 April 2017

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The Roles of APC and Axin Derived from Experimental and Theoretical Analysis of the Wnt Pathway

20 April 2017

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Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism

20 April 2017

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The Wnt signaling pathway in development and disease

20 April 2017

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Protein phosphatase 1 regulates assembly and function of the beta-catenin degradation complex

20 April 2017

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Cleavage of the Wnt receptor Ryk regulates neuronal differentiation during cortical neurogenesis

20 April 2017

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Wnt/beta-catenin signaling: components, mechanisms, and diseases

20 April 2017

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Arginine N-methyltransferase 1 is required for early postimplantation mouse development, but cells deficient in the enzyme are viable

20 April 2017

1 reference

https://api.crossref.org/works/10.1038/ONC.2010.610

SUMO-1 modification of the C-terminal KVEKVD of Axin is required for JNK activation but has no effect on Wnt signaling

20 April 2017

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The links between axin and carcinogenesis

20 April 2017

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Wnt-induced dephosphorylation of axin releases beta-catenin from the axin complex

20 April 2017

1 reference

https://api.crossref.org/works/10.1038/ONC.2010.610

Phosphorylation of axin, a Wnt signal negative regulator, by glycogen synthase kinase-3beta regulates its stability

20 April 2017

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Wnt signaling: a common theme in animal development

20 April 2017

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Protein arginine methylation in mammals: who, what, and why

20 April 2017

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Arginine methylation an emerging regulator of protein function

20 April 2017

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Linking colorectal cancer to Wnt signaling

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A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation

20 April 2017

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Arginine methylation at a glance

20 April 2017

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Protein interfaces in signaling regulated by arginine methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.610

Wnt signals across the plasma membrane to activate the beta-catenin pathway by forming oligomers containing its receptors, Frizzled and LRP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.610

Alternative splicing yields protein arginine methyltransferase 1 isoforms with distinct activity, substrate specificity, and subcellular localization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.610

PKCepsilon stimulated arginine methylation of RIP140 for its nuclear-cytoplasmic export in adipocyte differentiation

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2010.610

Gbetagamma activates GSK3 to promote LRP6-mediated beta-catenin transcriptional activity

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2010.610

Negative feedback regulation of Wnt signaling by Gbetagamma-mediated reduction of Dishevelled

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2010.610

The protein stability of Axin, a negative regulator of Wnt signaling, is regulated by Smad ubiquitination regulatory factor 2 (Smurf2)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.610

Axin: a master scaffold for multiple signaling pathways

21 January 2018

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Analysis of the yeast arginine methyltransferase Hmt1p/Rmt1p and its in vivo function. Cofactor binding and substrate interactions.

21 January 2018

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State of the arg: protein methylation at arginine comes of age.

21 January 2018

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WNTs modulate cell fate and behavior during vertebrate development

21 January 2018

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Arginine methylation of STAT1 modulates IFNalpha/beta-induced transcription

21 January 2018

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The physiological and pathophysiological role of PRMT1-mediated protein arginine methylation

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2010.610

Axin and hepatocellular carcinomas.

21 January 2018

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Frequent alterations in the Wnt signaling pathway in colorectal cancer with microsatellite instability

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2010.610

PRMT1 is the predominant type I protein arginine methyltransferase in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.610

Activation of nuclear receptor coactivator PGC-1alpha by arginine methylation

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2010.610

21 January 2018

Rethinking WNT signaling

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https://api.crossref.org/works/10.1038%2FONC.2010.610

Wnt signaling: is the party in the nucleus?

21 January 2018

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Culprits in the degradation of cyclin E apprehended

21 January 2018

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A mouse PRMT1 null allele defines an essential role for arginine methylation in genome maintenance and cell proliferation

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2010.610

Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2010.610

Methylation of RUNX1 by PRMT1 abrogates SIN3A binding and potentiates its transcriptional activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.610

Control of beta-catenin stability: reconstitution of the cytoplasmic steps of the wnt pathway in Xenopus egg extracts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.610

AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.610

The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.610

Dimensions Publication ID

31 March 2020

Identifiers

DOI

10.1038/ONC.2010.610

0 references

1050026359

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