Protein kinase C-theta-mediated signals enhance CD4+ T cell survival by up-regulating Bcl-xL (Q24337298)

negative regulation of T cell apoptotic process

GOA release 2020-03-11

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GOA release 2020-03-11

author name string

Santhakumar Manicassamy

1

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Sonal Gupta

2

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Zhaofeng Huang

3

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Zuoming Sun

Propriocidal apoptosis of mature T lymphocytes occurs at S phase of the cell cycle.

4

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language of work or name

English

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publication date

1 June 2006

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published in

Journal of Immunology

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volume

176

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issue

11

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page(s)

6709-16

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cites work

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.176.11.6709

7 January 2021

CD28 can promote T cell survival through a phosphatidylinositol 3-kinase-independent mechanism

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.176.11.6709

7 January 2021

Positive feedback regulation of PLCgamma1/Ca(2+) signaling by PKCtheta in restimulated T cells via a Tec kinase-dependent pathway.

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.176.11.6709

7 January 2021

Signal transduction by lymphocyte antigen receptors

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.176.11.6709

7 January 2021

CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-XL.

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.176.11.6709

7 January 2021

Differential roles of PKC-theta in the regulation of intracellular calcium concentration in primary T cells

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.176.11.6709

7 January 2021

Genetic dissection of antigen receptor induced-NF-kappaB activation

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.176.11.6709

7 January 2021

Akt Phosphorylation of BAD Couples Survival Signals to the Cell-Intrinsic Death Machinery

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.176.11.6709

7 January 2021

Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.176.11.6709

7 January 2021

Protein kinase Ctheta: a new essential superstar on the T-cell stage

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.176.11.6709

7 January 2021

AP-1 function and regulation

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.176.11.6709

7 January 2021

Induction of NF-kappaB by the Akt/PKB kinase

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.176.11.6709

7 January 2021

Low-affinity ligands for the TCR drive proliferation of mature CD8+ T cells in lymphopenic hosts

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.176.11.6709

7 January 2021

The roles of costimulation and Fas in T cell apoptosis and peripheral tolerance

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.176.11.6709

7 January 2021

The PI-3 kinase/Akt pathway and T cell activation: pleiotropic pathways downstream of PIP3

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.176.11.6709

7 January 2021

Three-dimensional segregation of supramolecular activation clusters in T cells

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.176.11.6709

7 January 2021

PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.176.11.6709

7 January 2021

Selective modulation of protein kinase C-theta during T-cell activation

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.176.11.6709

7 January 2021

CARMA1, BCL-10 and MALT1 in lymphocyte development and activation.

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.176.11.6709

7 January 2021

SPAK kinase is a substrate and target of PKCtheta in T-cell receptor-induced AP-1 activation pathway

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.176.11.6709

7 January 2021

Jun proteins modulate the ovary-specific promoter of aromatase gene in ovarian granulosa cells via a cAMP-responsive element

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.176.11.6709

7 January 2021

NF-kappa B activation induced by T cell receptor/CD28 costimulation is mediated by protein kinase C-theta

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.176.11.6709

7 January 2021

Bclx regulates the survival of double-positive thymocytes

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.176.11.6709

7 January 2021

Complex formation and cooperation of protein kinase C theta and Akt1/protein kinase B alpha in the NF-kappa B transactivation cascade in Jurkat T cells

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.176.11.6709

7 January 2021

Bcl-XL and Bcl-2 repress a common pathway of cell death

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.176.11.6709

7 January 2021

T-B cell interaction inhibits spontaneous apoptosis of mature lymphocytes in Bcl-2-deficient mice

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.176.11.6709

7 January 2021

Protein kinase B regulates T lymphocyte survival, nuclear factor kappaB activation, and Bcl-X(L) levels in vivo

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.176.11.6709

7 January 2021

Protein kinase C theta affects Ca2+ mobilization and NFAT cell activation in primary mouse T cells

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.176.11.6709

7 January 2021

Regulation of Bcl-xL: a little bit of this and a little bit of STAT.

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.176.11.6709

7 January 2021

PDK1 nucleates T cell receptor-induced signaling complex for NF-kappaB activation

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.176.11.6709

7 January 2021

Interleukin-3-Induced Phosphorylation of BAD Through the Protein Kinase Akt

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.176.11.6709

7 January 2021

Protein kinase C-theta isoenzyme selective stimulation of the transcription factor complex AP-1 in T lymphocytes

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.176.11.6709

7 January 2021

The Rel/NF-kappaB family directly activates expression of the apoptosis inhibitor Bcl-x(L).

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.176.11.6709

7 January 2021

Protein kinase C-theta participates in NF-kappaB activation induced by CD3-CD28 costimulation through selective activation of IkappaB kinase beta

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.176.11.6709

7 January 2021

The NF-kappa B cascade is important in Bcl-xL expression and for the anti-apoptotic effects of the CD28 receptor in primary human CD4+ lymphocytes

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.176.11.6709

7 January 2021

Protein kinase C-theta mediates a selective T cell survival signal via phosphorylation of BAD

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.176.11.6709

7 January 2021

Cutting edge: distinct motifs within CD28 regulate T cell proliferation and induction of Bcl-XL.

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.176.11.6709

7 January 2021

The antiapoptotic protein Bcl-xL is dispensable for the development of effector and memory T lymphocytes.

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.176.11.6709

7 January 2021

Stabilized beta-catenin extends thymocyte survival by up-regulating Bcl-xL

1 reference

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7 January 2021

Protein kinase C-theta is an early survival factor required for differentiation of effector CD8+ T cells.

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.176.11.6709

7 January 2021