Isolation and structural characterization of a cDNA clone encoding the human DNA repair protein for O6-alkylguanine (Q24336908)

DNA-methyltransferase activity

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

K Tano

1

K

Tano

1 reference

19 October 2023

S Shiota

2

S

Shiota

1 reference

19 October 2023

J Collier

3

J

Collier

1 reference

19 October 2023

R S Foote

4

R S

Foote

1 reference

19 October 2023

S Mitra

5

S

Mitra

1 reference

Proceedings of the National Academy of Sciences of the United States of America

19 October 2023

language of work or name

English

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publication date

January 1990

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published in

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volume

87

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issue

2

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page(s)

686-90

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cites work

Isolation and characterization of full-length cDNA clones for human alpha-, beta-, and gamma-actin mRNAs: skeletal but not cytoplasmic actins have an amino-terminal cysteine that is subsequently removed

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Molecular cloning and biological characterization of a human gene, ERCC2, that corrects the nucleotide excision repair defect in CHO UV5 cells

19 March 2017

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DNA sequencing with chain-terminating inhibitors

19 March 2017

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A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

19 March 2017

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A simple and very efficient method for generating cDNA libraries

19 March 2017

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Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mp18 and pUC19 vectors

19 March 2017

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Rapid and sensitive protein similarity searches

19 March 2017

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Sequence from picomole quantities of proteins electroblotted onto polyvinylidene difluoride membranes

19 March 2017

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Regulation and expression of the adaptive response to alkylating agents

19 March 2017

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Dideoxy sequencing method using denatured plasmid templates

19 March 2017

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Effect of dose fractionation on the ethylnitrosourea induction of specific-locus mutations in mouse spermatogonia

7 April 2017

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Regulation of the capacity for O6-methylguanine removal from DNA in human lymphoblastoid cells studied by cell hybridization

27 September 2017

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Active site and complete sequence of the suicidal methyltransferase that counters alkylation mutagenesis

27 September 2017

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The role of O6-methylguanine-DNA methyltransferase in cell survival, mutagenesis and carcinogenesis

27 September 2017

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O6-Alkylguanine-DNA alkyltransferase activity correlates with the therapeutic response of human rhabdomyosarcoma xenografts to 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea

27 September 2017

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Construction of an Escherichia coli K-12 ada deletion by gene replacement in a recD strain reveals a second methyltransferase that repairs alkylated DNA

27 September 2017

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DNA repair in human cells: from genetic complementation to isolation of genes

27 September 2017

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Rapid, large-scale purification and characterization of 'Ada protein' (O6 methylguanine-DNA methyltransferase) of E. coli

27 September 2017

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DNA-mediated transfer and expression of a human DNA repair gene that demethylates O6-methylguanine

27 September 2017

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Characterisation and nucleotide sequence of ogt, the O6-alkylguanine-DNA-alkyltransferase gene of E. coli

27 September 2017

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Lack of induction of O6-methylguanine-DNA methyltransferase in mammalian cells treated with N-methyl-N'-nitro-N-nitrosoguanidine.

27 September 2017

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O6-methylguanine-DNA methyltransferase in human fetal tissues: fetal and maternal factors

30 May 2018

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O6-alkylguanine-DNA alkyltransferase and sensitivity to procarbazine in human brain-tumor xenografts

30 May 2018

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Similar amino acid sequences revisited

30 May 2018

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Heterogeneity of O6-alkylguanine-DNA alkyltransferase activity in peripheral blood lymphocytes: relationship between this activity in lymphocytes and in lymphoblastoid lines from normal controls and from patients with Hodgkin's disease or non-Hodgki

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53330

Repair of alkylated DNA in Escherichia coli. Physical properties of O6-methylguanine-DNA methyltransferase.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53330

Removal of O6-methylguanine from DNA of normal and xeroderma pigmentosum-derived lymphoblastoid lines.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53330

Methylation of the O6 position of guanine in DNA is the most likely initiating event in carcinogenesis by methylating agents.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=53330

Possible Relevance of O–6 Alkylation of Deoxyguanosine to the Mutagenicity and Carcinogenicity of Nitrosamines and Nitrosamides

29 November 2018

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12 December 2020

High-level expression of the cloned ada gene of Escherichia coli by deletion of its regulatory sequence

1 reference

12 December 2020

Trials, costs and complications

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12 December 2020

Defective repair of alkylated DNA by human tumour and SV40-transformed human cell strains

1 reference

12 December 2020

Repair of O6-methylguanine in DNA by demethylation is lacking in Mer- human tumor cell strains

1 reference

12 December 2020

Purification and characterization of ribulose-5-phosphate kinase from spinach

1 reference

12 December 2020

Age-dependent modulation of tissue-specific repair activity for 3-methyladenine and O6-methylguanine in DNA in inbred mice

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.87.2.686

1 reference

release_keir4juya5hzpanoikwx2dc7uu

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4912524

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1 reference

4912524

1 reference