Planar cell polarity pathway regulates actin rearrangement, cell shape, motility, and nephrin distribution in podocytes (Q24318698)

Membrane associated guanylate kinase, WW and PDZ domain containing 2

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Dishevelled segment polarity protein 2

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VANGL planar cell polarity 2

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Dishevelled associated activator of morphogenesis 1

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Nephrosis 1, nephrin

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American Journal of Physiology - Renal Physiology

author name string

Sima Babayeva

series ordinal

1

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Yulia Zilber

series ordinal

2

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Elena Torban

series ordinal

3

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language of work or name

English

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publication date

February 2011

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published in

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volume

300

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issue

2

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page(s)

F549-60

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cites work

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The actin cytoskeleton of kidney podocytes is a direct target of the antiproteinuric effect of cyclosporine A.

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The ankyrin repeat protein Diego mediates Frizzled-dependent planar polarization

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Slit diaphragms contain tight junction proteins

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The balance between isoforms of the prickle LIM domain protein is critical for planar polarity in Drosophila imaginal discs

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Neph-Nephrin proteins bind the Par3-Par6-atypical protein kinase C (aPKC) complex to regulate podocyte cell polarity

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Wnt5a regulates directional cell migration and cell proliferation via Ror2-mediated noncanonical pathway in mammalian palate development

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MAGI-1 is a component of the glomerular slit diaphragm that is tightly associated with nephrin

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An essential role of the universal polarity protein, aPKClambda, on the maintenance of podocyte slit diaphragms

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The slit diaphragm: a signaling platform to regulate podocyte function

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Loss of podocyte aPKClambda/iota causes polarity defects and nephrotic syndrome

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Mice deficient in alpha-actinin-4 have severe glomerular disease

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Cell junction-associated proteins IQGAP1, MAGI-2, CASK, spectrins, and alpha-actinin are components of the nephrin multiprotein complex

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SRC-family kinase Fyn phosphorylates the cytoplasmic domain of nephrin and modulates its interaction with podocin

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Regulation of Frizzled by fat-like cadherins during planar polarity signaling in the Drosophila compound eye.

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MAGI-3 is involved in the regulation of the JNK signaling pathway as a scaffold protein for frizzled and Ltap

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The DIX domain targets dishevelled to actin stress fibres and vesicular membranes

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Glomerular Epithelium: Structural Alterations Induced by Polycations

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