Structure and control of the actin regulatory WAVE complex (Q24308919)

Rac family small GTPase 1

1 reference

Abl interactor 2

1 reference

BRICK1 subunit of SCAR/WAVE actin nucleating complex

1 reference

NCK associated protein 1

1 reference

WASP family member 2

1 reference

WASP family member 1

1 reference

Cytoplasmic FMR1 interacting protein 1

1 reference

negative regulation of stress fiber assembly

1 reference

author

Zbyszek Otwinowski

9

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Shae B Padrick

object named as

Shae B Padrick

3

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Dominika Borek

object named as

Dominika Borek

2

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Daniel D. Billadeau

8

object named as

Daniel D Billadeau

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author name string

Zhucheng Chen

1

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Timothy S Gomez

4

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Zoltan Metlagel

5

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Ayman M Ismail

6

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Junko Umetani

7

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Michael K Rosen

WASH and WAVE actin regulators of the Wiskott-Aldrich syndrome protein (WASP) family are controlled by analogous structurally related complexes

10

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language of work or name

English

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publication date

25 November 2010

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published in

Nature

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volume

468

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issue

7323

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page(s)

533-8

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cites work

1 reference

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The Arp2/3 activator WASH controls the fission of endosomes through a large multiprotein complex

19 March 2017

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A FAM21-containing WASH complex regulates retromer-dependent sorting

19 March 2017

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The fragile X syndrome protein represses activity-dependent translation through CYFIP1, a new 4E-BP

19 March 2017

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19 March 2017

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Hem-1 complexes are essential for Rac activation, actin polymerization, and myosin regulation during neutrophil chemotaxis

19 March 2017

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19 March 2017

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Inclusion of Scar/WAVE3 in a similar complex to Scar/WAVE1 and 2

19 March 2017

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Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein

19 March 2017

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Abi-2, a novel SH3-containing protein interacts with the c-Abl tyrosine kinase and modulates c-Abl transforming activity

19 March 2017

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Searching protein structure databases with DaliLite v.3

19 March 2017

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HKL-3000: the integration of data reduction and structure solution--from diffraction images to an initial model in minutes

19 March 2017

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Abelson-interactor-1 promotes WAVE2 membrane translocation and Abelson-mediated tyrosine phosphorylation required for WAVE2 activation

19 March 2017

1 reference

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Mechanism of regulation of WAVE1-induced actin nucleation by Rac1 and Nck

19 March 2017

1 reference

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Interaction of WASP/Scar proteins with actin and vertebrate Arp2/3 complex

19 March 2017

1 reference

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Sra-1 and Nap1 link Rac to actin assembly driving lamellipodia formation.

19 March 2017

1 reference

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The WASP-WAVE protein network: connecting the membrane to the cytoskeleton

19 March 2017

1 reference

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Physical mechanisms of signal integration by WASP family proteins.

7 April 2017

1 reference

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Activation of the WAVE complex by coincident signals controls actin assembly

27 September 2017

1 reference

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WASP and SCAR/WAVE proteins: the drivers of actin assembly

27 September 2017

1 reference

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Regulation of cell-cell adhesion by Abi/Diaphanous complexes.

27 September 2017

1 reference

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Hierarchical regulation of WASP/WAVE proteins

27 September 2017

1 reference

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Contact-dependent promotion of cell migration by the OL-protocadherin-Nap1 interaction

27 September 2017

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c-Abl-mediated phosphorylation of WAVE3 is required for lamellipodia formation and cell migration

27 September 2017

1 reference

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Actin-bound structures of Wiskott-Aldrich syndrome protein (WASP)-homology domain 2 and the implications for filament assembly.

27 September 2017

1 reference

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Critical conformational changes in the Arp2/3 complex are induced by nucleotide and nucleation promoting factor.

27 September 2017

1 reference

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The WASP-Arp2/3 pathway: genetic insights

27 September 2017

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Regulation of actin dynamics by WASP and WAVE family proteins.

27 September 2017

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p140Sra-1 (specifically Rac1-associated protein) is a novel specific target for Rac1 small GTPase.

27 September 2017

1 reference

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The WAVE regulatory complex is inhibited.

27 September 2017

1 reference

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c-Abl interacts with the WAVE2 signaling complex to induce membrane ruffling and cell spreading

30 May 2018

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PtdIns(3,4,5)P3 binding is necessary for WAVE2-induced formation of lamellipodia

30 May 2018

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Cdk5 phosphorylation of WAVE2 regulates oligodendrocyte precursor cell migration through nonreceptor tyrosine kinase Fyn.

30 May 2018

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Collaborative Computational Project, number 4: providing programs for protein crystallography

29 November 2018

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The Prader-Willi phenotype of fragile X syndrome

29 November 2018

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Src-dependent phosphorylation of Scar1 promotes its association with the Arp2/3 complex

29 November 2018

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A conserved amphipathic helix in WASP/Scar proteins is essential for activation of Arp2/3 complex

29 November 2018

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CYFIP/Sra-1 controls neuronal connectivity in Drosophila and links the Rac1 GTPase pathway to the fragile X protein.

29 November 2018

1 reference

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29 November 2018

A short history of SHELX

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Processing of X-ray diffraction data collected in oscillation mode

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[4] Combining constraints for electron-density modification

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The Buccaneer software for automated model building. 1. Tracing protein chains

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Coot: model-building tools for molecular graphics

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Refinement of macromolecular structures by the maximum-likelihood method

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The many faces of radiation-induced changes

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7 January 2021

Optimal description of a protein structure in terms of multiple groups undergoing TLS motion

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MolProbity: all-atom contacts and structure validation for proteins and nucleic acids

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https://api.crossref.org/works/10.1038%2FNATURE09623

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The WAVE2 complex regulates actin cytoskeletal reorganization and CRAC-mediated calcium entry during T cell activation

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https://api.crossref.org/works/10.1038%2FNATURE09623

7 January 2021

EMAN: semiautomated software for high-resolution single-particle reconstructions

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ConSurf 2005: the projection of evolutionary conservation scores of residues on protein structures

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7 January 2021

Identifiers

DOI

10.1038/NATURE09623

1 reference

Dimensions Publication ID

1046792367

0 references

1 reference

1 reference

PubMed publication ID

21107423

1 reference