Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter (Q24306825)

1 reference

GeneDB

5 February 2019

mitochondrial calcium uniporter

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Mitochondrial calcium uniporter

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positive regulation of mitochondrial calcium ion concentration

GOA release 2020-03-11

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Mitochondrial calcium uniporter

GOA release 2020-03-11

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GOA release 2020-03-11

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Victor E. Koteliansky

11

object named as

Victor Koteliansky

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Vamsi Mootha

12

object named as

Vamsi K Mootha

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Fabiana Perocchi

2

object named as

Fabiana Perocchi

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author name string

Joshua M Baughman

1

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Hany S Girgis

3

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Molly Plovanich

4

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Casey A Belcher-Timme

5

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Yasemin Sancak

6

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X Robert Bao

7

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Laura Strittmatter

8

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Olga Goldberger

9

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Roman L Bogorad

MICU1 encodes a mitochondrial EF hand protein required for Ca(2+) uptake

10

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language of work or name

English

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publication date

18 August 2011

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published in

Nature

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volume

476

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issue

7360

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page(s)

341-5

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cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3486726

From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus

19 March 2017

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A mitochondrial protein compendium elucidates complex I disease biology

19 March 2017

1 reference

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Expression analysis of G Protein-Coupled Receptors in mouse macrophages

19 March 2017

1 reference

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Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes

19 March 2017

1 reference

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Assigning protein functions by comparative genome analysis: Protein phylogenetic profiles

19 March 2017

1 reference

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Computational method to predict mitochondrially imported proteins and their targeting sequences

7 April 2017

1 reference

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A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen

7 April 2017

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Blue native electrophoresis for isolation of membrane protein complexes in enzymatically active form

7 April 2017

1 reference

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Synergistic Ca2+ responses by G{alpha}i- and G{alpha}q-coupled G-protein-coupled receptors require a single PLC{beta} isoform that is sensitive to both G{beta}{gamma} and G{alpha}q.

7 April 2017

1 reference

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Targeted delivery of RNAi therapeutics with endogenous and exogenous ligand-based mechanisms

27 September 2017

1 reference

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Nutrient-sensitized screening for drugs that shift energy metabolism from mitochondrial respiration to glycolysis

27 September 2017

1 reference

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A combinatorial library of lipid-like materials for delivery of RNAi therapeutics

27 September 2017

1 reference

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Calcium uptake by rat kidney mitochondria

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3486726

Mitochondrial transport of cations: channels, exchangers, and permeability transition.

27 September 2017

1 reference

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Transport of calcium by mitochondria

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3486726

Inhibition of mitochondrial calcium ion transport by an oxo-bridged dinuclear ruthenium ammine complex

27 September 2017

1 reference

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Rapid changes of mitochondrial Ca2+ revealed by specifically targeted recombinant aequorin

27 September 2017

1 reference

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TOPCONS: consensus prediction of membrane protein topology

27 September 2017

1 reference

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A survey of the interaction of calcium ions with mitochondria from different tissues and species

30 May 2018

1 reference

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Rational design of cationic lipids for siRNA delivery

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3486726

The mitochondrial calcium uniporter is a highly selective ion channel.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3486726

The role of calcium in the regulation of mitochondrial metabolism

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3486726

Specific inhibition of mitochondrial Ca++ transport by ruthenium red

29 November 2018

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12 December 2020

Respiratory enzymes in oxidative phosphorylation. I. Kinetics of oxygen utilization

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12 December 2020

Assaying protein import into mitochondria

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12 December 2020

Ca(2+) activation of heart mitochondrial oxidative phosphorylation: role of the F(0)/F(1)-ATPase

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12 December 2020

Ca ion uptake by rat kidney mitochondria and its dependence on respiration and phosphorylation

1 reference

12 December 2020

Identifiers

DOI

10.1038/NATURE10234

1 reference

Dimensions Publication ID

1006031160

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1 reference

1 reference

PubMed publication ID

21685886

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