Characterization and localization of a human serine racemase (Q24296479)

D-serine biosynthetic process

GOA release 2020-03-11

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GOA release 2020-03-11

author name string

Menghang Xia

1

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Yuan Liu

2

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David J Figueroa

3

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Chi-Sung Chiu

4

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Nan Wei

5

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Ann-Marie Lawlor

6

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Ping Lu

7

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Cyrille Sur

8

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Ken S Koblan

9

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Thomas M Connolly

Whole body autoradiographic study on the distribution of 14C-D-serine administered intravenously to rats

10

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language of work or name

English

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publication date

18 June 2004

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published in

Molecular Brain Research

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volume

125

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issue

1-2

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page(s)

96-104

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cites work

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Distribution of free D-serine in vertebrate brains

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Determination of free amino acid enantiomers in rat brain and serum by high-performance liquid chromatography after derivatization with N-tert.-butyloxycarbonyl-L-cysteine and o-phthaldialdehyde

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Glial transport of the neuromodulator D-serine

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Atypical neural messengers

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Cloning of the cDNA for the human NMDA receptor NR2C subunit and its expression in the central nervous system and periphery

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Neurobiology through the looking-glass: D-serine as a new glial-derived transmitter

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Exaggerated responses to chronic nociceptive stimuli and enhancement of N-methyl-D-aspartate receptor-mediated synaptic transmission in mutant mice lacking D-amino-acid oxidase

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Uptake of d- and l-serine in C6 glioma cells

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Human serine racemase: moleular cloning, genomic organization and functional analysis

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Involvement of D-amino acid oxidase in elimination of free D-amino acids in mice

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Functional comparison of D-serine and glycine in rodents: the effect on cloned NMDA receptors and the extracellular concentration.

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d -serine and serine racemase are present in the vertebrate retina and contribute to the physiological activation of NMDA receptors

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Genetic and physiological data implicating the new human gene G72 and the gene for D-amino acid oxidase in schizophrenia

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D-serine, an endogenous synaptic modulator: localization to astrocytes and glutamate-stimulated release

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Serine racemase: a glial enzyme synthesizing D-serine to regulate glutamate-N-methyl-D-aspartate neurotransmission

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Purification of serine racemase: biosynthesis of the neuromodulator D-serine

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D-serine is an endogenous ligand for the glycine site of the N-methyl-D-aspartate receptor

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