Regulation of immunity and oncogenesis by the IRF transcription factor family (Q24293755)

Interferon regulatory factor 3

Europe PubMed Central

title

Regulation of immunity and oncogenesis by the IRF transcription factor family (English)

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main subject

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GOA release 2020-03-11

apoptotic process

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GOA release 2020-03-11

author name string

David Savitsky

1

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Tomohiko Tamura

2

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Hideyuki Yanai

3

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Tadatsugu Taniguchi

Cancer Immunology, Immunotherapy

4

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language of work or name

English

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publication date

April 2010

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published in

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volume

59

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issue

4

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page(s)

489-510

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cites work

Shared and unique functions of the DExD/H-box helicases RIG-I, MDA5, and LGP2 in antiviral innate immunity

1 reference

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Toll-like receptor 9 signaling activates NF-kappaB through IFN regulatory factor-8/IFN consensus sequence binding protein in dendritic cells

21 January 2018

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IRF6 in development and disease: a mediator of quiescence and differentiation

21 January 2018

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IFN consensus sequence binding protein/IFN regulatory factor-8 guides bone marrow progenitor cells toward the macrophage lineage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

IFN-stimulated gene 15 is synergistically activated through interactions between the myelocyte/lymphocyte-specific transcription factors, PU.1, IFN regulatory factor-8/IFN consensus sequence binding protein, and IFN regulatory factor-4: characteriza

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

IFN consensus sequence binding protein (Icsbp) is critical for eosinophil development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

IFN regulatory factor 4 and 8 promote Ig light chain kappa locus activation in pre-B cell development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

Targeted disruption of IRF-1 or IRF-2 results in abnormal type I IFN gene induction and aberrant lymphocyte development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

IFN regulatory factor-1 negatively regulates CD4+ CD25+ regulatory T cell differentiation by repressing Foxp3 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

A novel interferon regulatory factor family transcription factor, ICSAT/Pip/LSIRF, that negatively regulates the activity of interferon-regulated genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

RNA interference reveals a role for TLR2 and TLR3 in the recognition of Leishmania donovani promastigotes by interferon-gamma-primed macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Role of IRF-1 and caspase-7 in IFN-gamma enhancement of Fas-mediated apoptosis in ACHN renal cell carcinoma cells

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Interferon regulatory factor-1 mediates interferon-gamma-induced apoptosis in ovarian carcinoma cells.

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Functionally inactivating point mutation in the tumor-suppressor IRF-1 gene identified in human gastric cancer

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

IRF-1 is an essential mediator in IFN-gamma-induced cell cycle arrest and apoptosis of primary cultured hepatocytes.

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

ICSAT overexpression is not sufficient to cause adult T-cell leukemia or multiple myeloma

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Cellular commitment to oncogene-induced transformation or apoptosis is dependent on the transcription factor IRF-1.

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

The IRF family, revisited

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

A signaling pathway mediating downregulation of BCL6 in germinal center B cells is blocked by BCL6 gene alterations in B cell lymphoma.

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Pathogen recognition and innate immunity

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Trex1 prevents cell-intrinsic initiation of autoimmunity

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Transcription factor E2-2 is an essential and specific regulator of plasmacytoid dendritic cell development

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Interferon regulatory factors are transcriptional regulators of adipogenesis

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Homeostatic erythropoiesis by the transcription factor IRF2 through attenuation of type I interferon signaling.

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

The KSHV immediate-early transcription factor RTA encodes ubiquitin E3 ligase activity that targets IRF7 for proteosome-mediated degradation

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Cell type-specific involvement of RIG-I in antiviral response

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Recognition of cytosolic DNA activates an IRF3-dependent innate immune response

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Graded expression of interferon regulatory factor-4 coordinates isotype switching with plasma cell differentiation

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Type I interferon [corrected] gene induction by the interferon regulatory factor family of transcription factors

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

The feedback phase of type I interferon induction in dendritic cells requires interferon regulatory factor 8.

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Regulation of immunoglobulin light-chain recombination by the transcription factor IRF-4 and the attenuation of interleukin-7 signaling.

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

The signal transducer STAT5 inhibits plasmacytoid dendritic cell development by suppressing transcription factor IRF8

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

IRF-4-binding protein inhibits interleukin-17 and interleukin-21 production by controlling the activity of IRF-4 transcription factor.

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Essential role of IRF-3 in lipopolysaccharide-induced interferon-beta gene expression and endotoxin shock

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

IRF-8/ICSBP and IRF-1 cooperatively stimulate mouse IL-12 promoter activity in macrophages

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Immunodeficiency and chronic myelogenous leukemia-like syndrome in mice with a targeted mutation of the ICSBP gene

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Interferon regulatory factors: the next generation

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

ICSBP directs bipotential myeloid progenitor cells to differentiate into mature macrophages.

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

CD8(+) T cell-mediated skin disease in mice lacking IRF-2, the transcriptional attenuator of interferon-alpha/beta signaling

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Regulation of LMP2 and TAP1 genes by IRF-1 explains the paucity of CD8+ T cells in IRF-1-/- mice.

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Multistage regulation of Th1-type immune responses by the transcription factor IRF-1

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Interferon regulatory factor-1 is required for a T helper 1 immune response in vivo

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

The interferon regulatory transcription factor IRF-1 controls positive and negative selection of CD8+ thymocytes.

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

IFN-gamma represses IL-4 expression via IRF-1 and IRF-2

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Virus infection induces the assembly of coordinately activated transcription factors on the IFN-beta enhancer in vivo

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Toll-like receptors and innate immunity

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Requirement for IRF-1 in the microenvironment supporting development of natural killer cells

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

An IRF-1-dependent pathway of DNA damage-induced apoptosis in mitogen-activated T lymphocytes

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Activation of a cell-cycle-regulated histone gene by the oncogenic transcription factor IRF-2.

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Cooperation of the tumour suppressors IRF-1 and p53 in response to DNA damage

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Viral targeting of DEAD box protein 3 reveals its role in TBK1/IKKepsilon-mediated IRF activation

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Recurrent translocations involving the IRF4 oncogene locus in peripheral T-cell lymphomas

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Integration of interferon-alpha/beta signalling to p53 responses in tumour suppression and antiviral defence.

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Identification of Lps2 as a key transducer of MyD88-independent TIR signalling

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

The protein kinase PKR is required for macrophage apoptosis after activation of Toll-like receptor 4.

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

IRF-7 is the master regulator of type-I interferon-dependent immune responses

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

IkappaB kinase-alpha is critical for interferon-alpha production induced by Toll-like receptors 7 and 9

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

IRF4 addiction in multiple myeloma

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

IFNalpha activates dormant haematopoietic stem cells in vivo.

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Deregulation of MUM1/IRF4 by chromosomal translocation in multiple myeloma

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

A common haplotype of interferon regulatory factor 5 (IRF5) regulates splicing and expression and is associated with increased risk of systemic lupus erythematosus

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Irf6 is a key determinant of the keratinocyte proliferation-differentiation switch

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Abnormal skin, limb and craniofacial morphogenesis in mice deficient for interferon regulatory factor 6 (Irf6)

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Mutations in IRF6 cause Van der Woude and popliteal pterygium syndromes

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Interferon-alpha induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

A Toll-like receptor-independent antiviral response induced by double-stranded B-form DNA.

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Transcription factor IRF4 controls plasma cell differentiation and class-switch recombination

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

The development of inflammatory T(H)-17 cells requires interferon-regulatory factor 4

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

The contribution of transcription factor IRF1 to the interferon-gamma-interleukin 12 signaling axis and TH1 versus TH-17 differentiation of CD4+ T cells

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

TNF activates an IRF1-dependent autocrine loop leading to sustained expression of chemokines and STAT1-dependent type I interferon–response genes

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Interferon regulatory factor-2 protects quiescent hematopoietic stem cells from type I interferon-dependent exhaustion.

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Papillomaviruses and cancer: from basic studies to clinical application

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

IRFs: master regulators of signalling by Toll-like receptors and cytosolic pattern-recognition receptors

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Insights into interferon regulatory factor activation from the crystal structure of dimeric IRF5

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Epigenetic disruption of interferon-gamma response through silencing the tumor suppressor interferon regulatory factor 8 in nasopharyngeal, esophageal and multiple other carcinomas.

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

1 reference

7 January 2021

Antiviral innate immunity pathways.

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Impaired myelopoiesis in mice devoid of interferon regulatory factor 1.

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Molecular signature of CD34(+) hematopoietic stem and progenitor cells of patients with CML in chronic phase.

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Expression of MUM1/IRF4 mRNA as a prognostic marker in patients with multiple myeloma

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Identification and characterization of nucleophosmin/B23/numatrin which binds the anti-oncogenic transcription factor IRF-1 and manifests oncogenic activity

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

HHV-8 encoded vIRF-1 represses the interferon antiviral response by blocking IRF-3 recruitment of the CBP/p300 coactivators

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Identification of the interferon regulatory factor 5 gene (IRF-5) as a direct target for p53.

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Repression of IRF-4 target genes in human T cell leukemia virus-1 infection

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Regulation of the IRF-1 tumour modifier during the response to genotoxic stress involves an ATM-dependent signalling pathway

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

A retroviral library genetic screen identifies IRF-2 as an inhibitor of N-ras-induced growth suppression in leukemic cells

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Low expression of interferon regulatory factor-1 and identification of novel exons skipping in patients with chronic myeloid leukaemia

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Epstein-Barr virus: the first human tumor virus and its role in cancer

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Common deleted region on the long arm of chromosome 5 in esophageal carcinoma.

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Negative regulation of IFN-alpha/beta signaling by IFN regulatory factor 2 for homeostatic development of dendritic cells

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Defective development of splenic and epidermal CD4+ dendritic cells in mice deficient for IFN regulatory factor-2.

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Critical roles of interferon regulatory factor 4 in CD11bhighCD8alpha- dendritic cell development

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Role of a transductional-transcriptional processor complex involving MyD88 and IRF-7 in Toll-like receptor signaling

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

The V proteins of paramyxoviruses bind the IFN-inducible RNA helicase, mda-5, and inhibit its activation of the IFN-beta promoter

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Immune evasion by hepatitis C virus NS3/4A protease-mediated cleavage of the Toll-like receptor 3 adaptor protein TRIF

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Partner-regulated interaction of IFN regulatory factor 8 with chromatin visualized in live macrophages.

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Interferon regulatory factor 4 negatively regulates the production of proinflammatory cytokines by macrophages in response to LPS

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Negative regulation of Toll-like-receptor signaling by IRF-4.

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Interferon regulatory factor-3 is an in vivo target of DNA-PK.

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Evidence for licensing of IFN-gamma-induced IFN regulatory factor 1 transcription factor by MyD88 in Toll-like receptor-dependent gene induction program

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Elevated level of SUMOylated IRF-1 in tumor cells interferes with IRF-1-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Role of IFN regulatory factor 5 transcription factor in antiviral immunity and tumor suppression

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

A cell-type-specific requirement for IFN regulatory factor 5 (IRF5) in Fas-induced apoptosis

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Regulation of innate immune responses by DAI (DLM-1/ZBP1) and other DNA-sensing molecules

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Interferon regulatory factor 4 differentially regulates the production of Th2 cytokines in naive vs. effector/memory CD4+ T cells

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

IRF7 activation by Epstein-Barr virus latent membrane protein 1 requires localization at activation sites and TRAF6, but not TRAF2 or TRAF3

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

A critical link between Toll-like receptor 3 and type II interferon signaling pathways in antiviral innate immunity

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Dysregulated T helper cell differentiation in the absence of interferon regulatory factor 4.

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Expression profiling of CD34+ hematopoietic stem/ progenitor cells reveals distinct subtypes of therapy-related acute myeloid leukemia.

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

The interferon-inducible murine p48 (ISGF3gamma) gene is regulated by protooncogene c-myc

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Cell Cycle Regulation of Histone H4 Gene Transcription Requires the Oncogenic Factor IRF-2

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Interleukin-12 induces expression of interferon regulatory factor-1 via signal transducer and activator of transcription-4 in human T helper type 1 cells.

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Activation of interferon regulatory factor 3 in response to DNA-damaging agents

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Inactivation of interferon regulatory factor-1 tumor suppressor protein by HPV E7 oncoprotein. Implication for the E7-mediated immune evasion mechanism in cervical carcinogenesis

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Oncogenic potential of a dominant negative mutant of interferon regulatory factor 3.

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Modulation of T cell cytokine production by interferon regulatory factor-4

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Virus-induced heterodimer formation between IRF-5 and IRF-7 modulates assembly of the IFNA enhanceosome in vivo and transcriptional activity of IFNA genes

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Interferon Regulatory Factor-2 Regulates Cell Growth through Its Acetylation

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Activation of the murine interleukin-12 p40 promoter by functional interactions between NFAT and ICSBP

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Identification of Ser-386 of interferon regulatory factor 3 as critical target for inducible phosphorylation that determines activation

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Poxvirus protein N1L targets the I-kappaB kinase complex, inhibits signaling to NF-kappaB by the tumor necrosis factor superfamily of receptors, and inhibits NF-kappaB and IRF3 signaling by toll-like receptors

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

The interferon consensus sequence-binding protein activates transcription of the gene encoding neurofibromin 1

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Synergistic activation of interleukin-12 p35 gene transcription by interferon regulatory factor-1 and interferon consensus sequence-binding protein

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

A CRM1-dependent nuclear export pathway is involved in the regulation of IRF-5 subcellular localization

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

IRF-8/interferon (IFN) consensus sequence-binding protein is involved in Toll-like receptor (TLR) signaling and contributes to the cross-talk between TLR and IFN-gamma signaling pathways

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Interferon regulatory factor-8 is indispensable for the expression of promyelocytic leukemia and the formation of nuclear bodies in myeloid cells

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Interferon regulatory factor 3 is regulated by a dual phosphorylation-dependent switch

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

The interferon consensus sequence-binding protein (ICSBP/IRF8) represses PTPN13 gene transcription in differentiating myeloid cells

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Functional characterization of murine interferon regulatory factor 5 (IRF-5) and its role in the innate antiviral response

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

The Kaposi's Sarcoma-associated Herpesvirus-encoded vIRF-3 Inhibits Cellular IRF-5

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

The interferon regulatory factor family in host defense: mechanism of action

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

The transcription factor interferon regulatory factor-1 is essential for natural killer cell function in vivo

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Crucial role of interferon consensus sequence binding protein, but neither of interferon regulatory factor 1 nor of nitric oxide synthesis for protection against murine listeriosis

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Interferon Consensus Sequence Binding Protein–deficient Mice Display Impaired Resistance to Intracellular Infection Due to a Primary Defect in Interleukin 12 p40 Induction

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Interferon (IFN) Consensus Sequence-binding Protein, a Transcription Factor of the IFN Regulatory Factor Family, Regulates Immune Responses In Vivo through Control of Interleukin 12 Expression

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

The Transcription Factor Interferon Regulatory Factor 1 (IRF-1) Is Important during the Maturation of Natural Killer 1.1+ T Cell Receptor–α/β+ (NK1+ T) Cells, Natural Killer Cells, and Intestinal Intraepithelial T Cells

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Regulation of apoptosis in myeloid cells by interferon consensus sequence-binding protein

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Deficiency in the transcription factor interferon regulatory factor (IRF)-2 leads to severely compromised development of natural killer and T helper type 1 cells

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Interferon regulatory factor 4 (IRF4) interacts with NFATc2 to modulate interleukin 4 gene expression

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

ICSBP is essential for the development of mouse type I interferon-producing cells and for the generation and activation of CD8alpha(+) dendritic cells

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Regulation of the germinal center gene program by interferon (IFN) regulatory factor 8/IFN consensus sequence-binding protein

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

The role of IRF-4 in transcriptional regulation

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Repression of DNA repair mechanisms in IRF-4-expressing and HTLV-I-infected T lymphocytes

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Crystal structure of an IRF-DNA complex reveals novel DNA recognition and cooperative binding to a tandem repeat of core sequences

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Disabled-2 is transcriptionally regulated by ICSBP and augments macrophage spreading and adhesion.

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

GAAP-1: a transcriptional activator of p53 and IRF-1 possesses pro-apoptotic activity

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Development of Th1 and not Th2 immune responses in mice lacking IFN-regulatory factor-4

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Molecular cloning of LSIRF, a lymphoid-specific member of the interferon regulatory factor family that binds the interferon-stimulated response element (ISRE).

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Down-regulation of interferon regulatory factor 4 gene expression in leukemic cells due to hypermethylation of CpG motifs in the promoter region

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Apoptosis is promoted by the dsRNA-activated factor (DRAF1) during viral infection independent of the action of interferon or p53.

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

IRF-4,8 orchestrate the pre-B-to-B transition in lymphocyte development

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Human papillomavirus 16 E6 oncoprotein binds to interferon regulatory factor-3 and inhibits its transcriptional activity

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Loss of transcription factor IRF-1 affects tumor susceptibility in mice carrying the Ha-ras transgene or nullizygosity for p53.

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Pip, a novel IRF family member, is a lymphoid-specific, PU.1-dependent transcriptional activator

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Interferon regulatory factor family of transcription factors and regulation of oncogenesis

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Triggering the interferon antiviral response through an IKK-related pathway

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Stimulus specificity of gene expression programs determined by temporal control of IKK activity

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

TLR3 deficiency in patients with herpes simplex encephalitis

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Requirement for the transcription factor LSIRF/IRF4 for mature B and T lymphocyte function

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Deletion of IRF-1, mapping to chromosome 5q31.1, in human leukemia and preleukemic myelodysplasia

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Anti-oncogenic and oncogenic potentials of interferon regulatory factors-1 and -2

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Inhibition of interferon regulatory factor 7 (IRF7)-mediated interferon signal transduction by the Kaposi's sarcoma-associated herpesvirus viral IRF homolog vIRF3.

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Rotavirus NSP1 inhibits expression of type I interferon by antagonizing the function of interferon regulatory factors IRF3, IRF5, and IRF7

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Functional analysis of human herpesvirus 8-encoded viral interferon regulatory factor 1 and its association with cellular interferon regulatory factors and p300.

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

The IRF-3 transcription factor mediates Sendai virus-induced apoptosis

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Interferon regulatory factor 3 is a cellular partner of rotavirus NSP1.

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Interferon regulatory factor 7 is associated with Epstein-Barr virus-transformed central nervous system lymphoma and has oncogenic properties

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Identification of TRAIL as an interferon regulatory factor 3 transcriptional target

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Leukemia-associated, constitutively active mutants of SHP2 protein tyrosine phosphatase inhibit NF1 transcriptional activation by the interferon consensus sequence binding protein

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Functional regulation of MyD88-activated interferon regulatory factor 5 by K63-linked polyubiquitination

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

TRAF6 and the three C-terminal lysine sites on IRF7 are required for its ubiquitination-mediated activation by the tumor necrosis factor receptor family member latent membrane protein 1

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Interferon regulatory factor 6 promotes cell cycle arrest and is regulated by the proteasome in a cell cycle-dependent manner

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Inhibition of p300 histone acetyltransferase by viral interferon regulatory factor

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Expression of interferon consensus sequence binding protein (ICSBP) is downregulated in Bcr-Abl-induced murine chronic myelogenous leukemia-like disease, and forced coexpression of ICSBP inhibits Bcr-Abl-induced myeloproliferative disorder

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Lysyl oxidase inhibits ras-mediated transformation by preventing activation of NF-kappa B.

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

IRF family of transcription factors as regulators of host defense

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Innate immune recognition

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

The IRF family transcription factors in immunity and oncogenesis

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Signaling through IFN regulatory factor-5 sensitizes p53-deficient tumors to DNA damage-induced apoptosis and cell death

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Repression of IFN regulatory factor 8 by DNA methylation is a molecular determinant of apoptotic resistance and metastatic phenotype in metastatic tumor cells

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Essential role for ICSBP in the in vivo development of murine CD8alpha + dendritic cells

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

The interferon regulatory factor ICSBP/IRF-8 in combination with PU.1 up-regulates expression of tumor suppressor p15(Ink4b) in murine myeloid cells

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

ICSBP/IRF-8 inhibits mitogenic activity of p210 Bcr/Abl in differentiating myeloid progenitor cells

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Interferon consensus sequence binding protein (ICSBP; IRF-8) antagonizes BCR/ABL and down-regulates bcl-2.

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

ICSBP is critically involved in the normal development and trafficking of Langerhans cells and dermal dendritic cells

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Identification of target genes and a unique cis element regulated by IRF-8 in developing macrophages.

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Negative control of basophil expansion by IRF-2 critical for the regulation of Th1/Th2 balance

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

The BXH2 mutation in IRF8 differentially impairs dendritic cell subset development in the mouse

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Interferon regulatory factors 4 and 8 induce the expression of Ikaros and Aiolos to down-regulate pre-B-cell receptor and promote cell-cycle withdrawal in pre-B-cell development

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

IRF8 regulates B-cell lineage specification, commitment, and differentiation

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Expression of interferon consensus sequence binding protein induces potent immunity against BCR/ABL-induced leukemia.

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Expression of nuclear transcription factor interferon consensus sequence binding protein in chronic myeloid leukemia correlates with pretreatment risk features and cytogenetic response to interferon-alpha

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

IRF-1 deficiency skews the differentiation of dendritic cells toward plasmacytoid and tolerogenic features.

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Expression of interferon regulatory factor 4 in chronic myeloid leukemia: correlation with response to interferon alfa therapy.

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Lipopolysaccharide stimulates the MyD88-independent pathway and results in activation of IFN-regulatory factor 3 and the expression of a subset of lipopolysaccharide-inducible genes

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Coordinate regulation of IFN consensus sequence-binding protein and caspase-1 in the sensitization of human colon carcinoma cells to Fas-mediated apoptosis by IFN-gamma

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Cutting edge: IFN consensus sequence binding protein/IFN regulatory factor 8 drives the development of type I IFN-producing plasmacytoid dendritic cells

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

IFN regulatory factor-2 deficiency revealed a novel checkpoint critical for the generation of peripheral NK cells

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

IFN regulatory factor-4 and -8 govern dendritic cell subset development and their functional diversity

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Stages of germinal center transit are defined by B cell transcription factor coexpression and relative abundance

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021

Murine dendritic cell type I IFN production induced by human IgG-RNA immune complexes is IFN regulatory factor (IRF)5 and IRF7 dependent and is required for IL-6 production

1 reference

https://api.crossref.org/works/10.1007%2FS00262-009-0804-6

7 January 2021