IKKepsilon is part of a novel PMA-inducible IkappaB kinase complex (Q22254561)

GOA release 2020-03-11

protein phosphorylation

1 reference

GOA release 2020-03-11

R T Peters

1

R T

Peters

1 reference

PubMed

3 April 2023

S M Liao

series ordinal

2

author given names

S M

author last names

Liao

1 reference

PubMed

3 April 2023

T Maniatis

series ordinal

3

author given names

T

author last names

Maniatis

1 reference

PubMed

Sequential DNA damage-independent and -dependent activation of NF-kappaB by UV

3 April 2023

language of work or name

English

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publication date

March 2000

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published in

Molecular Cell

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volume

5

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issue

3

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page(s)

513-22

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cites work

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Predicting coiled coils by use of pairwise residue correlations

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Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway

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Site-specific phosphorylation of IkappaBalpha by a novel ubiquitination-dependent protein kinase activity

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Characterization of a mutant cell line that does not activate NF-kappaB in response to multiple stimuli

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Positive and negative regulation of IkappaB kinase activity through IKKbeta subunit phosphorylation

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A cytokine-responsive IκB kinase that activates the transcription factor NF-κB

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Evidence for two catalytically active kinase domains in pp90rsk

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The 90-kDa Ribosomal S6 Kinase (pp90rsk) Phosphorylates the N-terminal Regulatory Domain of IκBα and Stimulates Its Degradation in Vitro

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NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses

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Identification of a novel cyclosporin-sensitive element in the human tumor necrosis factor alpha gene promoter

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A systematic analysis of the factors that determine the strength of pre-mRNA splicing enhancers.

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IkappaB kinases serve as a target of CD28 signaling

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Abnormal morphogenesis but intact IKK activation in mice lacking the IKKalpha subunit of IkappaB kinase

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7 January 2021

Induction of NF-kappaB by the Akt/PKB kinase

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T-cell subset-specific expression of the IL-4 gene is regulated by a silencer element and STAT6.

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Activation of IkappaB kinase beta by protein kinase C isoforms

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Substrate targeting in the ubiquitin system

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Activation of the IkappaB alpha kinase complex by MEKK1, a kinase of the JNK pathway

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MEKK1 activates both IkappaB kinase alpha and IkappaB kinase beta

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Ionizing radiation and short wavelength UV activate NF-kappaB through two distinct mechanisms

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Interaction of an Adenovirus E3 14.7-Kilodalton Protein with a Novel Tumor Necrosis Factor Alpha-Inducible Cellular Protein Containing Leucine Zipper Domains

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IKK1-deficient mice exhibit abnormal development of skin and skeleton

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Severe liver degeneration in mice lacking the IkappaB kinase 2 gene

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7 January 2021

Identification of a cell protein (FIP-3) as a modulator of NF-kappaB activity and as a target of an adenovirus inhibitor of tumor necrosis factor alpha-induced apoptosis

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7 January 2021

NF-kappaB-inducing kinase activates IKK-alpha by phosphorylation of Ser-176

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7 January 2021

A ubiquitin ligase complex essential for the NF-kappaB, Wnt/Wingless, and Hedgehog signaling pathways

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IKK-1 and IKK-2: Cytokine-Activated IκB Kinases Essential for NF-κB Activation

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IkappaB kinase (IKK)-associated protein 1, a common component of the heterogeneous IKK complex

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Prediction of the coding sequences of unidentified human genes. IV. The coding sequences of 40 new genes (KIAA0121-KIAA0160) deduced by analysis of cDNA clones from human cell line KG-1

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Differential regulation of IkappaB kinase alpha and beta by two upstream kinases, NF-kappaB-inducing kinase and mitogen-activated protein kinase/ERK kinase kinase-1

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7 January 2021

Role of IKK1 and IKK2 in lipopolysaccharide signaling in human monocytic cells

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NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

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NF-kappaB activation by a signaling complex containing TRAF2, TANK and TBK1, a novel IKK-related kinase

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7 January 2021

Identification and characterization of an IkappaB kinase

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7 January 2021

NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling

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IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex

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7 January 2021

Signal-induced degradation of I kappa B alpha requires site-specific ubiquitination

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7 January 2021

Ikappa Balpha is a target for the mitogen-activated 90kDa ribosomal S6 kinase

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IKK-i, a novel lipopolysaccharide-inducible kinase that is related to IkappaB kinases

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Limb and skin abnormalities in mice lacking IKKalpha

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7 January 2021

Embryonic lethality, liver degeneration, and impaired NF-kappa B activation in IKK-beta-deficient mice

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7 January 2021

IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK

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7 January 2021

Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation

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7 January 2021

The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation

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7 January 2021

Direct Phosphorylation of IB by IKK and IKK: Discrimination Between Free and NF-B-Bound Substrate

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7 January 2021

Direct phosphorylation of IkappaB by IKKalpha and IKKbeta: discrimination between free and NF-kappaB-bound substrate

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7 January 2021

10.1016/S1097-2765(00)80445-1

Identifiers

DOI

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